Results 21 to 30 of about 631,021 (368)

Human airway xenograft models of epithelial cell regeneration [PDF]

, 2000
Regeneration and restoration of the airway epithelium after mechanical, viral or bacterial injury have a determinant role in the evolution of numerous respiratory diseases such as chronic bronchitis, asthma and cystic fibrosis.
Puchelle Edith, Puchelle, Edith, Peault Bruno, Edith Puchelle, Bruno Peault, Peault, Bruno   +5 more
core   +1 more source

Airway function at one year: association with premorbid airway function, wheezing, and maternal smoking [PDF]

, 2001
Background - Impaired growth and development of the respiratory system during fetal and early postnatal life may have important implications for lung development and later lung health.
Wade, AM, Wade, A. M., Fletcher, M. E., C Dezateux, Dezateux, C., Dundas, I, Fletcher, ME, Stocks, J., Dundas, I., Stocks, J, Fletcher, Margaret, Dezateux, C   +11 more
core   +1 more source

TGF-β1 Activates Nasal Fibroblasts through the Induction of Endoplasmic Reticulum Stress

Biomolecules, 2020
(1) Background: Tissue remodeling and extracellular matrix (ECM) accumulation contribute to the development of chronic inflammatory diseases of the upper airway.
Jae-Min Shin, Ju-Hyung Kang, Joo-Hoo Park, Hyun-Woo Yang, Heung-Man Lee, Il-Ho Park   +5 more
doaj   +1 more source

Synergistic Exacerbation of Allergic Inflammation by Combined Exposure to Air-Pollutants in a Murine Model of Allergic Rhinitis [PDF]

Clinical and Experimental Otorhinolaryngology
Objectives Allergic rhinitis (AR) is a chronic inflammation of the nasal mucosa triggered by environmental allergens. Although its pathophysiology has been extensively investigated, the influence of environmental aggravating factors—particularly combined
Joo-Hoo Park, Jee Won Moon, Yeong-In Jo, Hwa Eun Yang, Subin Cho, Hyeongguk Son, Hyun-Woo Yang, Dae Jin Song, Il-Ho Park   +8 more
doaj   +1 more source

Can HRCT be used as a marker of airway remodelling in children with difficult asthma? [PDF]

, 2006
BACKGROUND: Whole airway wall thickening on high resolution computed tomography (HRCT) is reported to parallel thickening of the bronchial epithelial reticular basement membrane (RBM) in adult asthmatics. A similar relationship in children with difficult
Khoo L, Khoo, L, Payne, DN, Hansell DM, Bush, A, Saglani S, Saglani, S, Ujita, M, Jeffery, PK, Papaioannou G, Jeffery PK, Bush A, Papaioannou, G, Owens, C, Hansell, DM, Owens C, Payne DN, Owens, CM, Ujita M   +18 more
core   +1 more source

Mechanisms altering airway smooth muscle cell Ca(2+) homeostasis in two asthma models [PDF]

, 2008
Background: Asthma is characterized by airway remodeling, altered mucus production and airway smooth muscle cell (ASMC) contraction causing extensive airway narrowing. In particular, alterations of ASMC contractility seem to be of crucial importance. The
Kellner, Julia, Tantzscher, Juliane, Edelmann, Martin, Bergner, Albrecht, Oelmez, Hamza, Huber, Rudolf M., Fischer, Rainald   +6 more
core   +1 more source

Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose [PDF]

, 2013
Background Diabetes is a risk factor for respiratory infection, and hyperglycaemia is associated with increased glucose in airway surface liquid and risk of Staphylococcus aureus infection.
Garnett, James P, Tregoning, John S, Baines, DL, Baines, Deborah L, Knight, Gwenan M, Naik, S, Lindsay, JA, Tregoning, JS, Naik, Sonam, Garnett, JP, Baker, EH, Lindsay, Jodi A, Gill, S, Baker, Emma H, Gill, Simren, Knight, GM   +15 more
core   +1 more source

Inflammatory cytokines can be monitored in exhaled breath particles following segmental and inhalation endotoxin challenge in healthy volunteers

Scientific Reports, 2022
Particles in exhaled air (PEx) are generated when collapsed small airways reopen during breathing. PEx can be noninvasively collected by particle impaction, allowing the analysis of undiluted epithelial lining fluid (ELF).
Olaf Holz, Meike Müller, Saskia Carstensen, Anna-Carin Olin, Jens M. Hohlfeld   +4 more
doaj   +1 more source

Airway Remodeling in Asthma: Tumor of the Airway? [PDF]

Respiration, 2013
properties and the therapy has been shown to have an acute and sustained beneficial effect on lung function (changes in FEV 1 ) in chronic persistent asthma [6] . Antileukotrienes do not have major side effects and appear to be well tolerated by most patients [7] , but a limitation of their widespread use may be due to the large percentage of ...
Chun Y, Seow, Stephan, van Eeden
openaire   +2 more sources

Airway wall remodeling in asthma : novel mechanisms of human bronchial smooth muscle cells in the induction of angiogenesis [PDF]

, 2014
Asthma is a global major health concern and it affects estimated 300 million people. The prevalence of asthma is rising and there is no cure for asthma, only the symptoms can be controlled.
Keglowich, Laura Franziska
core   +1 more source