Results 21 to 30 of about 754,493 (312)

A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics

open access: yesNature Biomedical Engineering, 2021
The rapid repurposing of antivirals is particularly pressing during pandemics. However, rapid assays for assessing candidate drugs typically involve in vitro screens and cell lines that do not recapitulate human physiology at the tissue and organ levels.
L. Si   +37 more
semanticscholar   +1 more source

Evaluation of Swab-Seq as a scalable, sensitive assay for community surveillance of SARS-CoV-2 infection

open access: yesScientific Reports, 2022
The ongoing SARS-CoV-2 pandemic and subsequent demand for viral testing has led to issues in scaling diagnostic lab efforts and in securing basic supplies for collection and processing of samples. This has motivated efforts by the scientific community to
HyunJin Kang   +6 more
doaj   +1 more source

Biologics and airway remodeling in severe asthma

open access: yesAllergy. European Journal of Allergy and Clinical Immunology, 2022
Asthma is a chronic inflammatory airway disease resulting in airflow obstruction, which in part can become irreversible to conventional therapies, defining the concept of airway remodeling.
G. Varricchi   +9 more
semanticscholar   +1 more source

SARS-CoV2 in public spaces in West London, UK during COVID-19 pandemic

open access: yesBMJ Open Respiratory Research, 2023
Background Spread of SARS-CoV2 by aerosol is considered an important mode of transmission over distances >2 m, particularly indoors.Objectives We determined whether SARS-CoV2 could be detected in the air of enclosed/semi-enclosed public spaces.Methods
Prashant Kumar   +13 more
doaj   +1 more source

Cellular and functional heterogeneity of the airway epithelium

open access: yesMucosal Immunology, 2021
The airway epithelium protects us from environmental insults, which we encounter with every breath. Not only does it passively filter large particles, it also senses potential danger and alerts other cells, including immune and nervous cells.
Jordan D. Davis, T. Wypych
semanticscholar   +1 more source

Cytomegalovirus serology in young to mid‐adult life and decline of lung function

open access: yesThe Clinical Respiratory Journal, 2023
Introduction Cytomegalovirus (CMV) seropositivity has been recently linked to severity and progression of asthma, cystic fibrosis, and chronic obstructive pulmonary disease (COPD). To date, no longitudinal study has addressed the relation of CMV serology
Raffaella Nenna   +6 more
doaj   +1 more source

High cytomegalovirus serology and subsequent COPD-related mortality: a longitudinal study

open access: yesERJ Open Research, 2020
Background Positive serology for cytomegalovirus (CMV) has been associated with all-cause mortality risk but its role in COPD mortality is unknown. The objective of the present study was to assess the relationship between CMV serology and COPD mortality.
Raffaella Nenna   +7 more
doaj   +1 more source

Lost Airway in Airway

open access: yesSri Lankan Journal of Anaesthesiology, 2022
No abstract ...
Tejesh C. Anandaswamy   +2 more
openaire   +1 more source

Ultrasound cavitation: a reliable non-enzymatic method for adipose-derived mesenchymal stem cell (ADSC) isolation

open access: yesStem Cell Research & Therapy, 2023
Background Adipose tissue is known to serve as an abundant and readily accessible source of adipose-derived stem cells (ADSCs) as an alternative to bone marrow.
Joo-Hoo Park   +5 more
doaj   +1 more source

Consensus guidelines for managing the airway in patients with COVID‐19

open access: yesAnaesthesia, 2020
Severe acute respiratory syndrome‐corona virus‐2, which causes coronavirus disease 2019 (COVID‐19), is highly contagious. Airway management of patients with COVID‐19 is high risk to staff and patients. We aimed to develop principles for airway management
T. Cook   +5 more
semanticscholar   +1 more source

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