Results 21 to 30 of about 720,456 (307)

Patterns of recruitment and injury in a heterogeneous airway network model [PDF]

, 2015
In respiratory distress, lung airways become flooded with liquid and may collapse due to surface-tension forces acting on air-liquid interfaces, inhibiting gas exchange.
Cressoni M, Murphy SL, Oliver E. Jensen, Peter S. Stewart, The Acute Respiratory Distress Syndrome Network, Weibel ER   +5 more
core   +2 more sources

A Novel Technique for Laryngotracheal Reconstruction for Idiopathic Subglottic Stenosis [PDF]

, 2016
Idiopathic subglottic stenosis is the most challenging condition in the field of upper airway reconstruction. We describe a successful novel technique for enlarging the airway space at the site of the laryngotracheal anastomosis in very high-level ...
Andreetti, Claudio, Ciccone, Anna M, D'Andrilli, ANTONIO LUCIO, Ibrahim, Mohsen, Korasidis, Stylianos, Maurizi, Giulio, Rendina, Erino Angelo, Vanni, Camilla, Venuta, Federico   +8 more
core   +1 more source

Flow-volume curve analysis for predicting recurrence after endoscopic dilation of airway stenosis [PDF]

, 2019
The flow-volume curve is a simple test for diagnosing upper airway obstruction. We evaluated its use to predict recurrence in patients undergoing endoscopic dilation for treatment of benign upper airway ...
Andreetti, Claudio, Ardò, Nicoletta, Fiorelli, Alfonso, Loizzi, Domenico, Loizzi, Michele, Messina, Gaetana, Poggi, Camilla, Rendina, Erino Angelo, Santini, Mario, Serra, Nicola, Sollitto, Francesco, Venuta, Federico   +11 more
core   +1 more source

Obstructive Sleep Apnea: Emerging Treatments Targeting the Genioglossus Muscle [PDF]

, 2019
Obstructive sleep apnea (OSA) is characterized by repetitive episodes of upper airway obstruction caused by a loss of upper airway dilator muscle tone during sleep and an inadequate compensatory response by these muscles in the context of an anatomically
Cano-Pumarega, Irene, Castillo-García, María, García-Río, Francisco, Martínez-Sánchez, Ana Belén, Mediano, Olga, Ortigado, Ana, Resano, Pilar, Romero-Peralta, Sofia, Sánchez de la Torre, Manuel   +8 more
core   +2 more sources

Inflammatory cytokines can be monitored in exhaled breath particles following segmental and inhalation endotoxin challenge in healthy volunteers

Scientific Reports, 2022
Particles in exhaled air (PEx) are generated when collapsed small airways reopen during breathing. PEx can be noninvasively collected by particle impaction, allowing the analysis of undiluted epithelial lining fluid (ELF).
Olaf Holz, Meike Müller, Saskia Carstensen, Anna-Carin Olin, Jens M. Hohlfeld   +4 more
doaj   +1 more source

Gene therapy for allergic diseases [PDF]

, 2011
Airway diseases such as allergic asthma and rhinitis are characterized by a T-helper type 2 (Th2) response. Treatment of allergic airway diseases is currently limited to drugs that relieve disease symptoms and inflammation.
Joos, Guy, Maes, Tania, Tournoy, Kurt
core   +2 more sources

Tensin1 expression and function in chronic obstructive pulmonary disease [PDF]

, 2019
open access articleChronic obstructive pulmonary disease (COPD) constitutes a major cause of morbidity and mortality. Genome wide association studies have shown significant associations between airflow obstruction or COPD with a non-synonymous SNP in ...
Amrani, Y., Bradding, Peter, Brightling, C. E., Clark, K., Gooptu, B., Roach, K.M., Smallwood, Dawn T., Stylianou, P.   +7 more
core   +1 more source

Relationship between concavity of the flow-volume loop and small airway measures in smokers with normal spirometry

BMC Pulmonary Medicine, 2022
Background There is increasing evidence of small airway abnormalities in smokers despite normal spirometry. The concavity in the descending limb of the maximum expiratory flow curve (MEFV) is a recognised feature of obstruction and can provide ...
Hooria Alowiwi, Stella Watson, Kanika Jetmalani, Cindy Thamrin, David P. Johns, E. Haydn Walters, Gregory G. King   +6 more
doaj   +1 more source

Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice [PDF]

, 2016
Introduction: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not known.
De Beuckelaer, Ans, Grooten, Johan, Gustafsson, Jan-Ake, Lambrecht, Bart, Naessens, Thomas, Smet, Muriel, Steffensen, Knut R, Van Hoecke, Lien, Vander Beken, Seppe, Vergote, Karl, Willart, Monique   +10 more
core   +1 more source

A Multidomain Approach to Assessing the Convergent and Concurrent Validity of a Mobile Application When Compared to Conventional Methods of Determining Body Composition

Sensors, 2020
Determining body composition via mobile application may circumvent limitations of conventional methods. However, the accuracy of many technologies remains unknown. This investigation assessed the convergent and concurrent validity of a mobile application
Eric V. Neufeld, Ryan A. Seltzer, Tasnim Sazzad, Brett A. Dolezal   +3 more
doaj   +1 more source