Results 51 to 60 of about 631,021 (368)

Airway Inflammation and Airway Hyperresponsiveness [PDF]

open access: yes, 2021
Airway inflammation is a complex inflammatory process of airways involving the contribution of various cells, recruited and activated in asthmatic conditions, and the mediators released by them. However, major components contributing to this inflammation are eosinophils, mast cells, and lymphocytes.
Sheikh Rayees, Inshah Din
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13)

open access: yesEBioMedicine, 2017
Background: Rhinovirus infection is a major cause of asthma exacerbations. Objectives: We studied nasal and bronchial mucosal inflammatory responses during experimental rhinovirus-induced asthma exacerbations. Methods: We used nasosorption on days 0, 2–5
Trevor T. Hansel   +25 more
doaj   +1 more source

The Physiologically Difficult Airway

open access: yesAirway, 2021
The physiologically difficult airway is defined as one in which severe physiologic derangements place patients at increased risk of cardiovascular collapse and death during tracheal intubation and transition to positive pressure ventilation.
Bhavya Vakil   +2 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Post-traumatic Tracheal Rupture: Anaesthetic Management

open access: yesAirway, 2021
Traumatic tracheobronchial laceration can be potentially life-threatening and pose significant challenges for anaesthetic management. We would like to share our experience of managing a patient who had traumatic tracheal rupture, multiple rib fractures ...
Abhilasha Motghare   +4 more
doaj   +1 more source

The Role of Point of Care Ultrasound During Airway Assessment

open access: yes, 2023
Background/Purpose: An assessment of the airway is an essential component of the pre-anesthesia evaluation. The purpose of assessing the airway is to predict potential problems and develop a safe anesthetic management plan.
Benda, Nicholas, Van't Hof, Kathryn
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Anaesthetic Management of Subglottic Stenosis in Granulomatosis with Polyangiitis

open access: yesAirway, 2021
Granulomatosis with polyangiitis, earlier known as Wegener's granulomatosis, is an autoimmune vascular disorder in which small- and medium-sized vessels are affected.
Milin Shah, Hemlata Kapoor
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

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