Results 71 to 80 of about 631,021 (368)

Functional Precision Oncology Approach Using Nanoliter Droplet Array for Drug Sensitivity Testing in Lung Cancer

Advanced Healthcare Materials, EarlyView.
A miniaturized drug sensitivity and resistance testing (DSRT) workflow based on the Droplet Microarray (DMA) platform enables functional drug testing using minimal patient‐derived tumor material. By screening nanoliter‐scale droplets containing as few as 300 cells, this approach generates reproducible and tumor‐specific drug response profiles ...
Maryam Salarian, Vicky L. Schiling, Thomas Muley, Michael Allgäuer, Florian Eichhorn, Michael Meister, Marc A. Schneider, Anna A. Popova   +7 more
wiley   +1 more source

Does Prewarming of Tracheal Tubes Prevent Epistaxis Following Nasotracheal Intubation? A Prospective, Randomised, Single-Blind Study

Airway, 2019
Introduction: Nasotracheal intubation has always been considered more traumatic than orotracheal intubation. According to previous studies, warming of endotracheal tubes is a good practice because it softens the tube and increases its flexibility ...
Anuja Agrawal, Bhavika Sangada, Dinesh Chauhan, Tejash Sharma   +3 more
doaj   +1 more source

Analysis of airway secretions in a model of sulfur dioxide induced chronic obstructive pulmonary disease (COPD)

, 2006
Hypersecretion and chronic phlegm are major symptoms of chronic obstructive pulmonary disease (COPD) but animal models of COPD with a defined functional hypersecretion have not been established so far.
David A Groneberg, Wagner, Ulrich, Fischer, Axel, Groneberg, Jan David Alexander, Groneberg David A, Welte, Tobias, Fehmann Hans-Christoph, Staats Petra, Axel Fischer, Welte Tobias, Fischer Axel, Ulrich Wagner, Tobias Welte, Fehmann, Hans-Christoph, Petra Staats, Staats, Petra, Hans-Christoph Fehmann, Wagner Ulrich   +17 more
core   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Measurement of airway function using invasive and non-invasive methodsin mild and severe models for allergic airway inflammation in mice

, 2014
In this study a direct comparison was made between non-invasive and non-ventilated unrestrained whole body plethysmography (Penh) (conscious animals) and the invasive ventilated lung resistance (RL) method (anaesthetized animals) in both mild and severe ...
Johan eGarssen, Kim eVerheijden, Frank A Redegeld, Verheijden, Kim A T, Paul A. J. Henricks, Garssen, Johan, Pharmacology, Gert Folkerts, Sub Immunopharmacology, Sub Airway in vivo Pharmacology, Kim A. T. Verheijden, Redegeld, Frank A., Henricks, Paul A J, Frank A. Redegeld, Paul eHenricks, Folkerts, Gert, Gert eFolkerts, UIPS - Utrecht Institute for Pharmaceutical Sciences, Johan Garssen   +18 more
core   +1 more source

Direct in vivo gene transfer to the airway epithelium employing adenovirus-polylysine-DNA complexes [PDF]

, 1993
Adenovirus-polylysine-DNA complexes were evaluated for their capacity to accomplish direct in vivo gene transfer to airway epithelium employing a rodent model.
Miller, L., Rømer, M., Wagner, E., Harris, C. E., Hu, P.-C., Wagner, Ernst, Cotten, Matt, Cotten, M., Agarwal, Santosh, Curiel, David T., Agarwal, S., Gao, L., Harris, C., Romer, M., Curiel, D.   +14 more
core   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Interventional Bronchoscopy for Tracheal Tumours: An Anaesthetic Challenge

Airway, 2019
Tracheal tumours may present with potentially catastrophic airway obstruction. There are many challenges in the management of anaesthesia for obstructing intratracheal tumours by rigid bronchoscopy, such as difficulty in ventilation, securing airway ...
Jyoti Sharma, Prashant Kumar, Shweta Bhardwaj, Sumit Das   +3 more
doaj   +1 more source

Randomized crossover comparison between the i-gel and the LMA-Unique in anaesthetized, paralysed adults [PDF]

, 2009
<b>Background</b>: The i-gel differs from other supraglottic airway devices, in that it has a softer, non-inflatable cuff. This study was designed to compare the performance of the i-gel and the LMA-Unique (LMA-U) when used during anaesthesia
J. Kinsella, S. Gangaiah, Kinsella, J., Gangaiah, S., Fletcher, G., V. Uppal, G. Fletcher, Uppal, V.   +7 more
core   +1 more source

chenghongsheng/SC_RNAseq-airway-organoid: scRNAseq and Bulk RNAseq of COPD airway organoids

, 2022
This project contains the R scripts of single-cell and bulk transcriptomic analysis of airway organoids derived from healthy and chronic obstructive pulmonary disease (COPD) patients.
chenghongsheng
core   +1 more source