A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED [PDF]
American Journal of Respiratory and Critical Care Medicine, 2016 RATIONALE AND OBJECTIVES: Asthma is a heterogeneous disease driven by diverse immunologic and inflammatory mechanisms. We used transcriptomic profiling of airway tissues to help define asthma phenotypes. METHODS: The transcriptome from bronchial biopsies
Adcock, IM +28 more
core +5 more sources
Long-term outcomes of bronchial thermoplasty in subjects with severe asthma: A comparison of 3-year follow-up results from two prospective multicentre studies [PDF]
European Respiratory Journal, 2017 Bronchial thermoplasty is an endoscopic therapy for severe asthma. The previously reported, randomised sham-controlled AIR2 (Asthma Intervention Research 2) trial showed a significant reduction in severe asthma exacerbations, emergency department visits ...
Bansal, Sandeep +10 more
core +3 more sources
Recent developments regarding periostin in bronchial asthma
Allergology International, 2015 Although it is currently recognized that bronchial asthma is not a single disease but a syndrome, we have not yet made use of our new understanding of this heterogeneity as we treat asthma patients.
Kenji Izuhara +5 more
doaj +2 more sources
Bronchial Asthma in Youth: A Brief Concept Review [PDF]
ChildrenBronchial asthma is a respiratory chronic disorder frequently affecting youth. It is characterized by a huge personal, familial, and societal impact. Biological and cellular studies in recent decades define asthma as a chronic inflammatory disease of the
Roberto W. Dal Negro
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Development of a Personalized Pharmacologic Treatment Repository for Bronchial Asthma Based on the 2018 Guideline for the Diagnosis and Management of Bronchial Asthma in Primary Care（Practice Edition） [PDF]
Zhongguo quanke yixue, 2022 Bronchial asthma is a chronic inflammatory disease with high heterogeneity, polygenic inheritance, complex etiology and many complications. The effects of prevention and treatment for a bronchial asthma patient often depend on whether the patient has ...
HUO Hongmin, YANG Yaofang, DONG Jiatian, MAO Zixian, HU Ping, SONG Fengchun
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Bronchial Asthma, Airway Remodeling and Lung Fibrosis as Successive Steps of One Process
International Journal of Molecular Sciences, 2023 Bronchial asthma is a heterogeneous disease characterized by persistent respiratory system inflammation, airway hyperreactivity, and airflow obstruction.
I. Savin, M. Zenkova, A. Sen’kova
semanticscholar +1 more source
Comparison of oscillometry with lung function parameters between patients with stable bronchial asthma with airflow obstruction and chronic obstructive pulmonary disease [PDF]
BMC Pulmonary MedicineBackground Lung oscillometry is an emerging investigation for assessing patients with obstructive airway disease. Comparison of oscillometry parameters with bronchodilator responsiveness (BDR) between patients with bronchial asthma and chronic ...
Sajal De, Aakansha Ashok Sarda
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Federal guidelines on diagnosis and treatment of bronchial asthma
PULMONOLOGIYA, 2022 Bronchial asthma is a heterogeneous disease that requires identification of its phenotype and a personalized approach to therapy. At the same time, despite a wide range of therapeutic options, many patients with asthma cannot achieve control over the ...
A. Chuchalin +21 more
semanticscholar +1 more source
Planning a Clinical Development Programme for Medicines for Bronchial Asthma
Регуляторные исследования и экспертиза лекарственных средств, 2021 The need for development of a clinical trial guidance for medicines for bronchial asthma is brought about by the improvement of requirements for research programmmes for new medicines.
E. S. Petrova +2 more
doaj +1 more source
Аллергология и Иммунология в Педиатрии, 2023 Introduction. Today there has been a steady increase in the allergic pathology of the respiratory tract - bronchial asthma and allergic rhinitis in pediatric practice.
R. Z. Tikhonova, R. M. Fayzullina
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