Results 41 to 50 of about 572,905 (336)

Long-term outcomes of bronchial thermoplasty in subjects with severe asthma: a comparison of 3-year follow-up results from two prospective multicentre studies

European Respiratory Journal, 2017
Bronchial thermoplasty is an endoscopic therapy for severe asthma. The previously reported, randomised sham-controlled AIR2 (Asthma Intervention Research 2) trial showed a significant reduction in severe asthma exacerbations, emergency department visits ...
G. Chupp, M. Laviolette, L. Cohn, C. Mcevoy, S. Bansal, Adrián Shifren, S. Khatri, G. Grubb, Edmund A McMullen, Racho Strauven, J. Kline   +10 more
semanticscholar   +1 more source

Alteration of circulating type 2 follicular helper T cells and regulatory B cells underlies the comorbid association of allergic rhinitis with bronchial asthma.

Clinical Immunology, 2015
Allergic rhinitis (AR), the most common allergic disorder of the airway, is often accompanied by bronchial asthma. However, little is known about the mechanism by which AR advances to AR comorbid with bronchial asthma (AR+Asthma).
Ryuta Kamekura, K. Shigehara, Satsuki Miyajima, Sumito Jitsukawa, K. Kawata, Keiji Yamashita, Tomonori Nagaya, A. Kumagai, A. Sato, H. Matsumiya, Noriko Ogasawara, N. Seki, K. Takano, Y. Kokai, Hiroki Takahashi, T. Himi, S. Ichimiya   +16 more
semanticscholar   +1 more source

CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development [PDF]

, 2016
Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe forms of asthma. It has never been addressed whether SNPs in CHI3L1 and cord blood YKL-40 levels
Gorlanova, Olga, Olga Gorlanova, Latzin, Philipp, Frey, Urs, Jakob Usemann, Urs Frey, Philipp Latzin, Dominik Hartl, Mack, Ines, Hartl, Dominik, Schmidt, Anne, Röösli, Martin, Ines Mack, Usemann, Jakob, Martin Röösli, Anne Schmidt   +15 more
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BRONCHIAL ASTHMA SUPERVISION AMONG TEENAGERS

Педиатрическая фармакология, 2008
The article highlights the results of the act test based bronchial asthma supervision evaluation among teenagers and defines the interrelation of the objective and subjective asthma supervision parameters. The researchers examined 214 male teenagers aged
N.M. Nenasheva
doaj   +2 more sources

Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge

, 2012
Background: Both standard and low-dose allergen provocations are an established tool in asthma research to improve our understanding of the pathophysiological mechanism of allergic asthma.
Rose Markus A, Schulze, Johannes B., Schubert, Ralf, Ulrich Zissler, Sandra Voss, Stefan Zielen, Ralf Schubert, Johannes Schulze, Markus A Rose, Zissler, Ulrich, Zielen Stefan, Rose, Markus A., Zissler Ulrich, Schubert Ralf, Schulze Johannes, Voss, Sandra, Zielen, Stefan, Voss Sandra   +17 more
core   +1 more source

Omalizumab: clinical use for the management of asthma [PDF]

, 2012
Omalizumab, a humanized monoclonal antibody that binds circulating IgE antibody, is a treatment option for patients with moderate to severe allergic asthma whose asthma is poorly controlled with inhaled corticosteroids and inhaled long-acting ß2 agonist ...
Rekha Chaudhuri, Neil C. Thomson, Thomson, N.C., Chaudhuri, R.   +3 more
core   +1 more source

EXPRESSION OF SOCS3 AND SOCS5 MRNAS IN PERIPHERAL BLOOD MONONUCLEARS FROM THE PATIENTS WITH BRONCHIAL ASTHMA

Медицинская иммунология, 2014
We observed sixty patients with allergic bronchial asthma (ABA) and 54 with non-allergic bronchial asthma (NABA). Quantitative SOCS3 and SOCS5 mRNA expression was evaluated by means of real-time PCR. Eighteen healthy persons served as a control group. In
V. V. Lim, L. N. Sorokina, V. N. Mineev, M. A. Nyoma, V. I. Trofimov   +4 more
doaj   +1 more source

Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response

, 2012
Rhinovirus (RV) infection is a major cause of asthma exacerbations which may be due to a deficient innate immune response in the bronchial epithelium. We hypothesized that the pleiotropic cytokine, TGF-?, influences interferon (IFN) production by primary
Green, Ben, David Sammut (137689), Gisli Jenkins (137696), Bedke Nicole, Jenkins Gisli, Stephen T Holgate, Donna E Davies, Howarth, Peter H., Nicole Bedke (137686), Sammut, David, Jenkins, Gisli, Amanda Tatler, Holgate, Stephen T., Sammut David, Ben Green, Patrick Dennison, Stephen T. Holgate (137701), Valia Kehagia, Dennison Patrick, Holgate Stephen T., David Sammut, Amanda Tatler (137698), Davies Donna E., Nicole Bedke, Donna E. Davies (137702), Bedke, Nicole, Peter H Howarth, Green Ben, Peter H. Howarth (137699), Patrick Dennison (137694), Davies, Donna E., Valia Kehagia (137692), Gisli Jenkins, Tatler, Amanda, Tatler Amanda, Howarth Peter H., Ben Green (137690), Dennison, Patrick, Kehagia, Valia, Kehagia Valia   +39 more
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Functional Relaxation and Guided Imagery as Complementary Therapy in Asthma: A Randomized Controlled Clinical Trial [PDF]

, 2009
Background: Asthma is a frequently disabling and almost invariably distressing disease that has a high overall prevalence. Although relaxation techniques and hypnotherapeutic interventions have proven their effectiveness in numerous trials, relaxation ...
N. Sauer, F. Röhricht, D. Nowak, Loew, T., C. Lahmann, T. Schuster, Sauer, N., Nowak, Dennis, K. Tritt, M. Nickel, T. Loew, Ronel, J., M. Noll-Hussong, Schuster, T., Tritt, K., Noll-Hussong, M., J. Ronel, Lahmann, Claas, Lahmann, C., Röhricht, F., Nickel, M., Nowak, D.   +21 more
core   +1 more source

Unifying candidate gene and GWAS Approaches in Asthma. [PDF]

, 2010
The first genome wide association study (GWAS) for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS ...
Heinzmann, Andrea, Ruether, Andreas, Otto Laub, Bufe, A., Lathrop, M, Schedel, M., Michel, Sven, Ruether, A., Michel, S., Schreiber, Stefan, von Berg, A., Gut, I.G., Christian Vogelberg, Ernst Rietschel, von Mutius, E., Burkhard Simma, Schreiber, S., Klopp, N., Schedel, Michaela, Depner, Martin, Laub, O., Liang, Liming, Stefan Schreiber, Illig, T., Rietschel, E., Michael Kabesch, Gut, Ivo Glynne, Mutius, Erika von, Frischer, T., Kabesch, Michael, Kabesch, M., Lathrop, Mark, Frischer, Thomas, Ashish Kumar, Jon Genuneit, Gut, Ivo G., Albrecht Bufe, Mark Lathrop, Kumar, A., Rietschel, Ernst, Ivo G. Gut, Illig, Thomas, Martin Depner, Liming Liang, Heinzmann, A., Andrea von Berg, Laub, Otto, Thomas Illig, Andreas Ruether, Simma, B., Vogelberg, Christian, Bufe, Albrecht, Erika von Mutius, Simma, Burkhard, Ivo G Gut, Kumar, Ashish, Sven Michel, Liang, L.M., Depner, M., Berg, Andrea von, Thomas Frischer, Michaela Schedel, Genuneit, J., Genuneit, Jon, Vogelberg, C., Norman Klopp, Klopp, Norman, Andrea Heinzmann   +67 more
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