Results 1 to 10 of about 4,122,734 (351)

Clinical remission in severe asthma with biologic therapy: an analysis from the UK Severe Asthma Registry

European Respiratory Journal, 2023
Background Novel biologic therapies have revolutionised the management of severe asthma with more ambitious treatment aims. Here we analyse the definition of clinical remission as a suggested treatment goal and consider the characteristics associated ...
P. McDowell, Ronald McDowell, John Busby, M. Eastwood, P. Patel, D. Jackson, Adel H Mansur, M. Patel, Hassan Burhan, S. Doe, Rekha Chaudhuri, Robin Gore, J. W. Dodd, D. Subramanian, Thomas Brown, L. Heaney, Chiesi. L.G. Heaney   +16 more
semanticscholar   +1 more source

SANI definition of Clinical Remission in Severe Asthma: a Delphi consensus.

Journal of Allergy and Clinical Immunology: In Practice, 2023
Severe Asthma affects about 10% of the asthmatic population, and it is characterized by a low lung function and a higher count of blood leucocytes, mainly eosinophils.
G. Canonica, F. Blasi, G. E. Carpagnano, G. Guida, E. Heffler, P. Paggiaro   +5 more
semanticscholar   +1 more source

Analysis of comorbidities and multimorbidity in adult patients in the International Severe Asthma Registry.

Annals of Allergy, Asthma & Immunology, 2023
BACKGROUND Investigation for the presence of asthma comorbidities is recommended by GINA as their presence can complicate asthma management. OBJECTIVE To understand the prevalence and pattern of comorbidities and multimorbidity in adults with severe ...
G. Scelo, C. Torres-Duque, J. Maspero, Trung Nghia Tran, R. Murray, N. Martin, A. Menzies-Gow, M. Hew, M. Peters, Peter G. Gibson, G. Christoff, Todor A Popov, A. Côté, C. Bergeron, D. Dorscheid, J. FitzGerald, K. Chapman, L. Boulet, M. Bhutani, M. Sadatsafavi, Libardo Jiménez-Maldonado, Mauricio Durán-Silva, Bellanid Rodriguez, C. Celis-Preciado, D. Cano-Rosales, Iván Solarte, María José Fernández-Sánchez, Patricia Parada-Tovar, A. V. Bülow, A. Bjerrum, C. Ulrik, K. Assing, L. Rasmussen, S. Hansen, A. Altraja, A. Bourdin, C. Taillé, J. Charriot, N. Roche, A. Papaioannou, K. Kostikas, N. Papadopoulos, S. Salvi, D. Long, P. Mitchell, Richard E. Costello, C. Sirena, C. Cardini, E. Heffler, F. Puggioni, G. W. Canonica, G. Guida, T. Iwanaga, M. Al‐Ahmad, D. Linnemann, U. García, P. Kuna, J. Fonseca, R. Al-Lehebi, M. Koh Siyue, C. Rhee, B. Cosío, Luis Pérez de Llano, Diahn-Warng Perng (Steve), E. Huang, Hao-Chien Wang, M. Tsai, B. Mahboub, Laila Ibraheem Jaber Salameh, D. Jackson, J. Busby, L. Heaney, P. Pfeffer, A. Goddard, E. Wang, F. Hoyte, M. Wechsler, Nicholas Chapman, R. Katial, V. Carter, L. Bulathsinhala, N. Eleangovan, C. Ariti, Juntao Lyu, D. Price, C. Porsbjerg   +85 more
semanticscholar   +1 more source

Assessing adherence to inhaled therapies in asthma and the emergence of electronic monitoring devices

European Respiratory Review, 2022
Infrequent use of inhaled corticosteroids (ICS) and/or over-reliance of short-acting β-agonists (SABA) are recognised as key contributors to increased morbidity and mortality in asthma.
Hetal Dhruve, David J. Jackson
doaj   +1 more source

Biologics and airway remodeling in severe asthma

Allergy. European Journal of Allergy and Clinical Immunology, 2022
Asthma is a chronic inflammatory airway disease resulting in airflow obstruction, which in part can become irreversible to conventional therapies, defining the concept of airway remodeling.
G. Varricchi, S. Ferri, J. Pepys, R. Poto, G. Spadaro, E. Nappi, G. Paoletti, J. C. Virchow, E. Heffler, W. Canonica   +9 more
semanticscholar   +1 more source

Severe asthma [PDF]

Journal of Allergy and Clinical Immunology, 2006
Key pointsNot all patients with “difficult-to-control” asthma have “severe asthma”. Many of them have either an incorrect diagnosis, or mild-moderate asthma with unrecognised aggravating factors, or are non-compliant with prescribed therapy.For a diagnosis of severe asthma, it is necessary to confirm the diagnosis of asthma, to evaluate and treat ...
Susan, Foley, Qutayba, Hamid
openaire   +3 more sources

A patient case demonstrating the efficacy of benralizumab in uncontrolled severe eosinophilic asthma refractory to omalizumab and mepolizumab treatment

Respiratory Medicine Case Reports, 2021
Severe eosinophilic asthma is associated with a heavy burden and impact on daily living in patients experiencing uncontrolled symptoms, exacerbations, and treatment side effects.
John Davison, Simon Doe
doaj   +1 more source

Clinical Remission in Severe Asthma: A Pooled Post Hoc Analysis of the Patient Journey with Benralizumab

Advances in Therapy, 2022
Consensus definitions for clinical remission and super-response were recently established for severe asthma. Benralizumab is an interleukin-5 (IL-5) receptor α-directed monoclonal antibody for severe, uncontrolled asthma; efficacy and safety were ...
A. Menzies-Gow, F. Hoyte, D. Price, D. Cohen, P. Barker, J. Kreindler, M. Jison, Christopher L. Brooks, Peggy Papeleu, R. Katial   +9 more
semanticscholar   +1 more source

Associations of symptoms of anxiety and depression with health-status, asthma control, dyspnoea, dysfunction breathing and obesity in people with severe asthma

Respiratory Research, 2022
Background Anxiety and depression are comorbidities of severe asthma. However, clinical characteristics associated with coexisting severe asthma and anxiety/depression are poorly understood.
Michelle A. Stubbs, Vanessa L. Clark, Peter G. Gibson, Janelle Yorke, Vanessa M. McDonald   +4 more
doaj   +1 more source

Severe Eosinophilic Asthma [PDF]

Journal of Clinical Medicine, 2019
Asthma is a heterogeneous disease with varying severity. Severe asthma is a subject of constant research because it greatly affects patients’ quality of life, and patients with severe asthma experience symptoms, exacerbations, and medication side effects.
Bakakos, A., Loukides, S., Bakakos, P.
openaire   +3 more sources