Results 11 to 20 of about 313,837 (264)

Small Airways Disease Adversely Impacts the Response to Biologic Therapies in Severe Asthma [PDF]

Pulmonary Therapy
Introduction Small airways disease (SAD) is increasingly recognized as a relevant trait in severe asthma, but its influence on outcomes with biologic therapies remains uncertain.
Chiara Allegrini, Elisa Bentivegna, Alessia Catalisano, Greta Insalata, Rubina Giulia Girolamo, Martina Maria Marinato, Luca Paita, Alessandra Sorano, Chiara Marzi, Clara De Filippis, Federico Lavorini, Gianna Camiciottoli   +11 more
doaj   +2 more sources

Is it severe asthma or asthma with severe comorbidities?

Journal of Asthma and Allergy, 2017
Luisa Brussino,1 Paolo Solidoro,2 Giovanni Rolla1 1Allergy and Clinical Immunology, University of Torino and Mauriziano Hospital, 2SC Pneumologia U, AOU Città della Salute e della Scienza, Torino, Italy Abstract: Severe asthma is defined as asthma
Brussino L, Solidoro P, Rolla G
doaj   +5 more sources

Severe asthma in children: Evaluation and management

Allergology International, 2019
Severe asthma in children is associated with significant morbidity. Children with severe asthma are at increased risk for adverse outcomes including medication-related side effects, life-threatening exacerbations, and impaired quality of life.
Mehtap Haktanir Abul, Wanda Phipatanakul
doaj   +3 more sources

Assessing adherence to inhaled therapies in asthma and the emergence of electronic monitoring devices

European Respiratory Review, 2022
Infrequent use of inhaled corticosteroids (ICS) and/or over-reliance of short-acting β-agonists (SABA) are recognised as key contributors to increased morbidity and mortality in asthma.
Hetal Dhruve, David J. Jackson
doaj   +1 more source

A patient case demonstrating the efficacy of benralizumab in uncontrolled severe eosinophilic asthma refractory to omalizumab and mepolizumab treatment

Respiratory Medicine Case Reports, 2021
Severe eosinophilic asthma is associated with a heavy burden and impact on daily living in patients experiencing uncontrolled symptoms, exacerbations, and treatment side effects.
John Davison, Simon Doe
doaj   +1 more source

Associations of symptoms of anxiety and depression with health-status, asthma control, dyspnoea, dysfunction breathing and obesity in people with severe asthma

Respiratory Research, 2022
Background Anxiety and depression are comorbidities of severe asthma. However, clinical characteristics associated with coexisting severe asthma and anxiety/depression are poorly understood.
Michelle A. Stubbs, Vanessa L. Clark, Peter G. Gibson, Janelle Yorke, Vanessa M. McDonald   +4 more
doaj   +1 more source

Severe Eosinophilic Asthma [PDF]

Journal of Clinical Medicine, 2019
Asthma is a heterogeneous disease with varying severity. Severe asthma is a subject of constant research because it greatly affects patients’ quality of life, and patients with severe asthma experience symptoms, exacerbations, and medication side effects.
Bakakos, A., Loukides, S., Bakakos, P.
openaire   +3 more sources

A feasibility randomised controlled trial of Novel Activity Management in severe ASthma-Tailored Exercise (NAMASTE): yoga and mindfulness

BMC Pulmonary Medicine, 2021
Background Physical inactivity is common in severe asthma and associated with poor health outcomes. New approaches are needed to address physical inactivity in this group.
Sarah A. Hiles, Paola D. Urroz, Peter G. Gibson, Adam Bogdanovs, Vanessa M. McDonald   +4 more
doaj   +1 more source

Phenotype overlap in the natural history of asthma

European Respiratory Review, 2023
The heterogeneity of asthma makes it challenging to unravel the pathophysiologic mechanisms of the disease. Despite the wealth of research identifying diverse phenotypes, many gaps still remain in our knowledge of the disease's complexity.
Fabio L.M. Ricciardolo, Giuseppe Guida, Francesca Bertolini, Antonino Di Stefano, Vitina Carriero   +4 more
doaj   +1 more source

What matters to people with severe asthma? Exploring add-on asthma medication and outcomes of importance

ERJ Open Research, 2021
There is an increasing number of new therapies for severe asthma; however, what outcomes people with severe asthma would like improved and what aspects they prioritise in new medications remain unknown.
Vanessa L. Clark, Peter G. Gibson, Vanessa M. McDonald   +2 more
doaj   +1 more source