Results 11 to 20 of about 312,536 (265)
Frontiers in Medicine, 2022 BackgroundAtopic dermatitis (AD) is regarded as a chronic systemic disease which is characterized by a robust overexpression of type 2 related cytokines, with increased total IgE levels and a concomitant sensitization to common allergens.
Ruperto González-Pérez +5 more
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Severe Asthma in Children [PDF]
The Journal of Allergy and Clinical Immunology: In Practice, 2014 Severe asthma in children is characterized by sustained symptoms despite treatment with high doses of inhaled corticosteroids or oral corticosteroids. Children with severe asthma may fall into 2 categories, difficult-to-treat asthma or severe therapy-resistant asthma. Difficult-to-treat asthma is defined as poor control due to an incorrect diagnosis or
Theresa W, Guilbert +2 more
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Imaging for precision medicine: can V‐P SPECT measure mepolizumab response in asthma?
Respirology Case Reports, 2021 Monoclonal antibody therapies are effective for many but not all people with severe asthma. Precision medicine guides treatment selection using biomarkers to select patients most likely to respond according to their inflammatory endotypes.
Vanessa M. McDonald +5 more
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Respiratory Medicine Case Reports, 2022 Severe eosinophilic asthma is associated with a high corticosteroid burden, particularly in patients with comorbid chronic sinusitis/nasal polyps. This case study reports a 33-year-old woman who presented to the severe asthma center with uncontrolled ...
Adel H. Mansur, PhD FRCP
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Application of an algorithm to analyze patterns of intermittent oral corticosteroid use in asthma
npj Primary Care Respiratory Medicine, 2023 An algorithm to describe patterns of intermittent oral corticosteroid use in the UK (n = 476,167) found that one-third of patients receiving intermittent oral corticosteroids for asthma only had short gaps (
John Haughney +11 more
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BMC Pulmonary Medicine, 2021 Background Benralizumab, a monoclonal antibody targeting the human interleukin-5 (IL-5) receptor (IL-5R), was used before marketing authorisation in Spain in a real world setting as part of an early-access programme (EAP) to treat patients with severe ...
Eva Martínez-Moragón +4 more
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Depiction of Major Mite Allergens in Severe Allergic Rhinitis with High Mite Perennial Exposure
Turkish Archives of Otorhinolaryngology, 2020 Objective: Airway diseases, including allergic rhinitis, are prompted by specific IgE antibodies against airborne allergens and notably those derived from mites.
Ruperto González-Pérez +3 more
doaj +1 more source
Biologics and global burden of asthma: A worldwide portrait and a call for action
World Allergy Organization Journal, 2021 Biologics for severe asthma can significantly impact on the burden of disease and also have the potential to reduce asthma mortality. By reviewing the literature and contacting the pharmaceutical companies, the present paper aims at providing a worldwide
M. Caminati +6 more
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Critical evaluation of asthma biomarkers in clinical practice
Frontiers in Medicine, 2022 The advent of personalized medicine has revolutionized the whole approach to the management of asthma, representing the essential basis for future developments.
Giuseppe Guida +14 more
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Journal of Respiration, 2023 Introduction: Asthma and bronchiectasis are often partners in a complex but uneven relationship with asthma receiving more attention. The aim of this study is to describe how bronchiectasis is investigated in some Severe Asthma (SA) Centers, scattered ...
Giovanna Elisiana Carpagnano +10 more
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