Results 41 to 50 of about 4,122,734 (351)

Influence of chronic azithromycin treatment on the composition of the oropharyngeal microbial community in patients with severe asthma [PDF]

, 2017
Background: This study of the oropharyngeal microbiome complements the previously published AZIthromycin in Severe ASThma (AZISAST) clinical trial, where the use of azithromycin was assessed in subjects with exacerbationprone severe asthma.
Brusselle, Guy, Dauwe, Kenny, Deschaght, Pieter, Deschepper, Ellen, Joos, Guy, Jordens, Paul, Lopes dos Santos Santiago, Guido, Vaneechoutte, Dries, Vaneechoutte, Mario, Verhofstede, Chris   +9 more
core   +1 more source

Feasibility of Discontinuing Biologics in Severe Asthma: An Algorithmic Approach

Journal of Asthma and Allergy, 2021
In severe asthma with type 2 (T2) inflammation, biologics targeting key mediators of T2 inflammation, including interleukin (IL)-5, IL-4/IL-13, and immunoglobulin (Ig)E, remarkably improve the management of severe asthma, providing new insights into the ...
K. Hamada, K. Oishi, Y. Murata, Tsunahiko Hirano, K. Matsunaga   +4 more
semanticscholar   +1 more source

Bronchial thermoplasty : a new therapeutic option for the treatment of severe, uncontrolled asthma in adults [PDF]

, 2014
Bronchial thermoplasty is a young yet promising treatment for severe asthma whose benefit for long-term asthma control outweighs the short-term risk of deterioration and hospitalisation in the days following the treatment.
Alagha, Khuder, Aubier, Michel, Boulet, Louis Philippe, Brillet, Pierre Yves, Chanez, Pascal, Dombret, Marie-Christine, Joos, Guy, Laviolette, Michel, Louis, Renaud, Rochat, Thierry, Soccal, Paola   +10 more
core   +5 more sources

Critical evaluation of asthma biomarkers in clinical practice

Frontiers in Medicine, 2022
The advent of personalized medicine has revolutionized the whole approach to the management of asthma, representing the essential basis for future developments.
Giuseppe Guida, Diego Bagnasco, Vitina Carriero, Francesca Bertolini, Fabio Luigi Massimo Ricciardolo, Stefania Nicola, Luisa Brussino, Emanuele Nappi, Emanuele Nappi, Giovanni Paoletti, Giovanni Paoletti, Giorgio Walter Canonica, Giorgio Walter Canonica, Enrico Heffler, Enrico Heffler   +14 more
doaj   +1 more source

Guideline on management of the acute asthma attack in children by Italian Society of Pediatrics. [PDF]

, 2018
BACKGROUND: Acute asthma attack is a frequent condition in children. It is one of the most common reasons for emergency department (ED) visit and hospitalization. Appropriate care is fundamental, considering both the high prevalence of asthma in children,
Chiappini, E, Corsello, G, Indinnimeo, L, Miraglia del Giudice, M   +3 more
core   +1 more source

Is Bronchiectasis (BE) Properly Investigated in Patients with Severe Asthma? A Real-Life Report from Eight Italian Centers

Journal of Respiration, 2023
Introduction: Asthma and bronchiectasis are often partners in a complex but uneven relationship with asthma receiving more attention. The aim of this study is to describe how bronchiectasis is investigated in some Severe Asthma (SA) Centers, scattered ...
Giovanna Elisiana Carpagnano, Vitaliano Nicola Quaranta, Claudia Crimi, Pierachille Santus, Francesco Menzella, Corrado Pelaia, Giulia Scioscia, Cristiano Caruso, Elena Bargagli, Nicola Scichilone, Eva Polverino   +10 more
doaj   +1 more source

The Endogenous Th17 Response in NO2-Promoted Allergic Airway Disease Is Dispensable for Airway Hyperresponsiveness and Distinct from Th17 Adoptive Transfer [PDF]

, 2013
Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma. IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease.
A Abe, A Duguet, A Hoshino, A Vazquez-Tello, A Vazquez-Tello, AG Besnard, AG Besnard, AI Caceres, AJ Coyle, AR Brasier, AR Sousa, AS Saffar, AT Hastie, B Korkmaz, Benjamin T. Suratt, BJ Canning, C Sutton, C Taube, D Stejskal, Daniel J. Weiss, DB Corry, DC Newcomb, DC Newcomb, DC Newcomb, DH Broide, E Goleva, F Kirstein, GJ Zijlstra, H Fujie, H Koga, H Wakashin, Hong Wei Chu, I Tillie-Leblond, J Agbetile, J Chang, J Seok, J Sunyer, J Zhao, JB Cowland, Jennifer L. Ather, JH Bates, JH Lee, JL Ather, JL Ather, John F. Alcorn, JR Karlsen, JV Fahy, K Raemdonck, K Yang, L McKinley, LA Cooney, Laura Hoyt, Lennart K. A. Lundblad, LJ Akinbami, LK Lundblad, LK Lundblad, LK Lundblad, LL Reber, M Bevelander, M Kawaguchi, M Kudo, M Leppkes, M Suzukawa, MA Willart, Matthew E. Poynter, ME Poynter, ME Poynter, ME Poynter, MH Brutsche, MH Shaw, MW Kinyanjui, N Schmitz, PA Wark, PL Delamater, PS Foster, PW Hellings, Q Wang, R He, RA Martin, Rebecca A. Martin, Rebecca Daggett, RH Wilson, S Ano, S Dragon, S Ferretti, S Haak, S Lajoie, S Molet, S Schnyder-Candrian, S Suzuki, S Wenzel, SJ Ballantyne, SM Hu, SP Chapoval, SR Hodgkins, T Li, VJ Johnson, W Al-Ramli, WP Arend, WW Lee, X Yao, XY Chi, Y Chung, Y Liu, Y Takenoue, Y Zhao, YH Wang   +106 more
core   +3 more sources

Assessing severe asthma [PDF]

European Respiratory Journal, 2016
Structured assessment of patients identifies asthma misdiagnosis, and improves asthma control and quality of life http://ow.ly ...
openaire   +2 more sources

Severe asthma features in children: A case-control online survey [PDF]

, 2016
Background: Very few studies have explored the distinguishing features of severe asthma in childhood in Europe, and only one study was conducted in Southern Europe.
Aralla, R, Baraldi, E, Benedictis, F, Berardi, M, Brunetti, L, Cardinale, F, Cazzato, S, Cutrera, R, Fenu, G, FERRANTE, Giuliana, LA GRUTTA, Stefania, Lombardi, E, Montella, S, Palmo, E, Piacentini, G, Pillo, S, Rusconi, F., SANTAMARIA, Francesca, Ullmann, N   +18 more
core   +1 more source

Severe asthma and asthma control in schoolchildren [PDF]

, 2013
Background: Asthma is a major health problem in children and most troublesome during severe or persistent symptoms. Children with problematic severe asthma have a disproportionate consumption of health care, despite high-dose treatment with inhaled ...
Nordlund, Björn
core   +1 more source