Results 51 to 60 of about 2,200,340 (304)

Severe Asthma in Adults

American Journal of Respiratory and Critical Care Medicine, 2005
Abstract Severe asthma remains poorly understood and frustrating to care for, partly because it is a heterogeneous disease. Patients with severe asthma disproportionately consume health care resources related to asthma. Severe asthma may develop over time, or shortly after onset of the disease.
openaire   +3 more sources

Asthma heterogeneity and severity [PDF]

World Allergy Organization Journal, 2016
Asthma is a common, chronic inflammatory airways disease characterized by a clinical syndrome of bronchial hyperresponsiveness, inflammation, and reversible airflow obstruction. Individuals with asthma can vary widely in clinical presentation, severity, and pathobiology.
Tara F. Carr, Eugene Bleecker
openaire   +3 more sources

Exhaled nitric oxide as a predictor of exacerbation in children with moderate-to-severe asthma: a prospective, 5-month study

, 2009
Background: Inhaled corticosteroids (ICSs) are recommended as the first line of treatment in children with moderate-to-severe asthma. Exhaled nitric oxide (ENO) has been proposed as a clinically useful marker of control that might help identify patients ...
CABRAL, Anna Lucia B., BARBIROTTO, Rosa M., MARTINS, Milton A., VOLLMER, William M., Anna Lúcia B. Cabral, Milton A. Martins, William M. Vollmer, Rosa M. Barbirotto   +7 more
core   +1 more source

Airway wall remodeling in asthma : novel mechanisms of human bronchial smooth muscle cells in the induction of angiogenesis [PDF]

, 2014
Asthma is a global major health concern and it affects estimated 300 million people. The prevalence of asthma is rising and there is no cure for asthma, only the symptoms can be controlled.
Keglowich, Laura Franziska
core   +1 more source

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

Arthritis Care &Research, EarlyView.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo, Bhavisha Desai, Abiola Oladapo, Nana Kragh, Rebekah Zincavage, Brad Padilla, Naomi Schlesinger   +6 more
wiley   +1 more source

Tezepelumab in near-fatal asthma requiring VV-ECMO

Respiratory Medicine Case Reports
Phase III studies have demonstrated that the anti-TSLP biologic tezepelumab significantly reduces asthma exacerbations in severe asthma, regardless of endotype. However, evidence on its use in near-fatal asthma is lacking. Tezepelumab's ability to reduce
Elisa Bentivegna, Greta Insalata, Luca Paita, Alessia Catalisano, Chiara Allegrini, Giovanni Cianchi, Manuela Bonizzoli, Federico Lavorini, Gianna Camiciottoli   +8 more
doaj   +1 more source

Prevalence of Comorbidities in Adults with Severe Asthma: Results from the International Severe Asthma Registry (ISAR)

, 2022
Rationale: Severe asthma accounts for 3-10% of the total population of patients with asthma. Comorbid conditions are common in patients with asthma and can complicate asthma management in multiple ways. Data are scarce on the prevalence and patterns of
Eleangovan, N, Barker, P, Lyu, J, Carter, V, Martin, N, Altraja, A, FitzGerald, JM, Hansen, S, Tran, TN, Porsbjerg, CM, Katial, R, Ariti, C, Scelo, G, Heaney, LG, Rhee, CK, et al., T.N. Tran, P. Barker, N. Martin, A. von Bulow, S. Hansen, P.E. Pfeffer, F. Puggioni, M.J. Tsai, E. Wang, M. Hew, C. Ariti, R. Katial, J.M. FitzGerald, D.B. Price, V. Carter, N. Eleangovan, G. Scelo, J. Lyu, M. Koh Siyue, A. Altraja, C.K. Rhee, C.M. Porsbjerg, null on behalf of the ISAR PRISM Working Group, L.G. Heaney   +39 more
core   +1 more source

The Development of Rheumatoid Arthritis–Specific Ambulatory Care–Sensitive Conditions: Results of a Consensus Process

Arthritis Care &Research, EarlyView.
Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin, Candace H. Feldman, Claire E. H. Barber, Gabriel Fabreau, Jake Jennings, Scott Patten, Cheryl Barnabe, Inflammatory Arthritis‐Specific ACSC Consensus Process Working Group   +7 more
wiley   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

The Role of Primary Care in Asthma Control and Severity

Spectrum, 2019
Background: Asthma is a common chronic inflammatory disease of the airways affecting 3 million Canadians. Primary Care Providers (PCPs) are integral to care coordination, enhanced through the development of a strong patient-PCP relationship with ...
Joel Agarwal, Monette Dimitrov, Kerri MacKay, Alan Kaplan, Donald Cockcroft, Dilini Vethanayagam   +5 more
doaj   +1 more source