Enzymatic Effectiveness of Alcoholic and Aqueous Extract of Salvia Officinalis in Mice Poisoned with Tetrachloride [PDF]
Archives of Razi Institute, 2021 Regarding the antioxidant, anti-inflammatory, and antibacterial effects of Salvia officnalis (S. officinalis) extracts and the use of medicinal herbs as an alternative to chemical drugs, this study aimed to evaluate the enzymatic changes and reduction of
R Kadhim, N. H Ali, D Aziz Ibrahim
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Indirubin alleviates CCl4-induced liver fibrosis by regulation of TGF-β-mediated signaling pathways [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Liver fibrosis is a common liver disease caused by chronic liver damage. However, there are currently no approved drugs available to treat it. Therefore, the therapeutic effect of indirubin on liver fibrosis was evaluated.
Xiaoying Li, Yuanzhi Yao, Lin Wei
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Evaluation of the ameliorative role of ginger (Zingiber officinale) extract against carbon tetrachloride-induced hepatotoxicity in male albino rats [PDF]
Journal of Medical and Life Science, 2023 Background: One well-known hepatotoxin that is frequently used to cause acute toxic liver injury in a variety of experimental animals is carbon tetrachloride (CCl4).
Olfat Elghareeb +3 more
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Біологія тварин, 2021 This study aims to explore the ameliorative effects of L-glutamic acid (L-Glu) against carbon tetrachloride (CCl4) toxicity in male rats. Changes in the activities of alanine and aspartate aminotransferases (ALAT, ASAT) were studied in the tissues and ...
N. O. Salyha
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Carbon tetrachloride-induced acute liver toxicity: selecting dosage and biomarkers for evaluating hepatoprotective drugs in ICR outbred mice [PDF]
Pharmaceutical Sciences Asia, 2022 Evaluating effects of putative chemical or herbal agents against a single intraperitoneal administration of carbon tetrachloride (CCl4) in rodents is a widely used model for studying hepatoprotective potency.
Theerut Luangmonkong +9 more
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Hepatoprotective Role of Caesalpinia bonduc: A Histopathological and Biochemical Study [PDF]
Journal of Clinical and Diagnostic Research, 2014 Background: Hepatotoxicity is one of the inevitable side effects of long term use of medicines in many different disorders, chronic use of alcohol and in certain infectious disorders.
Suhani Sumalatha +3 more
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Genome-wide DNA methylation dynamics in carbon tetrachloride-induced mice liver fibrosis [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Many persistent harmful stimuli can result in chronic liver diseases, which lead to about 2 million deaths per year in the whole world. Liver fibrosis was found to exist in all kinds of chronic liver diseases.
Deming Li +5 more
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Сибирский онкологический журнал, 2021 Introduction. Serum chemokines are inflammatory mediators, which role is shown in the occurrence and progression of a number of malignant tumors. Produced by white blood cells, stem cells, tumor and endothelial cells, chemokines control their movement ...
S. O. Gening +7 more
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Shiyan dongwu yu bijiao yixue, 2021 ObjectiveTo investigate the effects of carbon tetrachloride (CCl4) on cardiac function and morphology in rats with acute liver injury.MethodsRat models of acute liver injury were established by intraperitoneal injection with different concentrations of ...
ZHANG Lili +6 more
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Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles. [PDF]
, 2020 Alcoholic liver disease (ALD) is a leading cause of cirrhosis in the United States, which is characterized by extensive deposition of extracellular matrix proteins and formation of a fibrous scar.
Baglieri, Jacopo +16 more
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