The aflatoxin B1-fumonisin B1 toxicity in BRL-3A hepatocytes is associated to induction of cytochrome P450 activity and arachidonic acid metabolism [PDF]
, 2017 Human oral exposure to aflatoxin B1 (AFB1) and fumonisin B1 (FB1) is associated with increased hepatocellular carcinoma. Although evidence suggested interactive AFB1–FB1 hepatotoxicity, the underlying mechanisms remain mostly unidentified.
Arias, Silvina Lorena +5 more
core +1 more source
Nigerian Postgraduate Medical Journal, 2012 Aims and objectives: The aim of this study was to determine the incidence of hepatotoxicity of HAART in HIV infected patients in a tertiary health centre in Nigeria.
R A Ugiagbe +3 more
doaj
The safety of herbal medicinal products [PDF]
, 2011 The primary aim of the EU, with the registration of herbal medicinal products (HMPs), is the protection of the European citizens from fraudulent and unsafe products.
Attard, Everaldo
core
Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. [PDF]
, 2016 BackgroundExcess body burden of uric acid promotes gout. Diminished renal clearance of uric acid causes hyperuricemia in most patients with gout, and the renal urate transporter (URAT)1 is important for regulation of serum uric acid (sUA) levels.
Girardet, Jean-Luc +12 more
core +2 more sources
Complications leading to hospitalization due to consumption of anti-TB drugs in patients with tuberculosis in Gorgan, Iran (2007-12) [PDF]
, 2015 Background and Objective: Anti tuberculosis drugs therapy is the most effective method for controling the tuberculosis (TB). Early detection and appropriate treatment can prevent the TB-drug resistance.
Abbasi, A. +4 more
core
A rapid stability-indicating, fused-core HPLC method for simultaneous determination of β-artemether and lumefantrine in anti-malarial fixed dose combination products [PDF]
, 2013 Background: Artemisinin-based fixed dose combination (FDC) products are recommended by World Health Organization (WHO) as a first-line treatment. However, the current artemisinin FDC products, such as beta-artemether and lumefantrine, are inherently ...
Bracke, Nathalie +8 more
core +2 more sources
TIPS and HCC: friends or foes ? [PDF]
, 2016 Portal hypertension and hepatocellular carcinoma [HCC] are major complications of liver cirrhosis and may coexist in the same patient. Transjugular intrahepatic portosystemic shunt [TIPS] is an effective treatment for recurrent variceal bleeding
DE SANTIS, Adriano
core
Environment InternationalMicro- and nanoplastics (MNPs) are increasingly recognized as novel environmental pollutants given their potential risks to ecosystems and human health. The liver, a vital organ for maintaining systemic homeostasis, exhibits heightened susceptibility to ...
Qiyue Wang +5 more
doaj +1 more source
Voriconazole-Induced Hepatotoxicity in a Patient with Pulmonary Aspergillosis: A Case Report
Infection and Drug Resistance, 2023 Li Gu,1 Tao Ai,2 Ling Pang,1 Dong Xu,1 Han Wang3 1Department and Institute of Infectious Disease, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonostic Infectious Disease, Huazhong University of ...
Gu L, Ai T, Pang L, Xu D, Wang H
doaj
ABCB1 Polymorphism in HIV-Infected Individuals Taking Antiretroviral Drugs
AIDS Research and TreatmentABC transporter P-glycoprotein (P-gp) and its expression enhance elimination and reduce drug exposure. The elimination of non-nucleoside reverse-transcriptase inhibitor (NNRTIs) drugs is associated with ABCB1 gene.
HariOm Singh +2 more
doaj +1 more source