Results 21 to 30 of about 79,483 (168)
PLoS ONE, 2010 BackgroundThe majority of antiretroviral treatment programmes in sub-Saharan Africa are scaling up antiretroviral treatment using a fixed dose first-line antiretroviral regimen containing stavudine, lamivudine, and nevirapine. One of the primary concerns
Kathryn M Chu +5 more
doaj +1 more source
Pharmaceuticals, 2022 Toosendanin (TSN) is a triterpenoid from the fruit or bark of Melia toosendan Sieb et Zucc, which has clear antitumor and insecticidal activities, but it possesses limiting hepatotoxicity in clinical application.
Li Luo +7 more
doaj +1 more source
Risk factors for erlotinib-induced hepatotoxicity: a retrospective follow-up study
BMC Cancer, 2018 Background Erlotinib is a drug used for the treatment of non-small cell lung cancer (NSCLC) and pancreatic cancer. Severe hepatotoxicity was observed in 4% to 31% of patients receiving erlotinib treatment prompting delay or termination of treatment. Only
Min Kyoung Kim +5 more
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Molecular Genetics & Genomic Medicine, 2020 Background Plasma concentrations of antiretrovirals (ARVs) regimens have considerably varied in individuals of human immunodeficiency virus (HIV) because of variations in the expression of drug‐metabolizing and transporter genes.
HariOm Singh +3 more
doaj +1 more source
Scientific ReportsAs part of supportive therapy, prophylaxis with tiopronin for injection (TI) against common hepatotoxicity complications has often been used. However, methods to prevent hepatotoxicity have not been established. Therefore, our study was aimed to find out
Hongye Yang +6 more
doaj +1 more source
Acetaminophen Hepatotoxicity [PDF]
Seminars in Liver Disease, 2019 AbstractAcetaminophen (APAP) is one of the most popular and safe pain medications worldwide. However, due to its wide availability, it is frequently implicated in intentional or unintentional overdoses where it can cause severe liver injury and even acute liver failure (ALF).
Anup, Ramachandran, Hartmut, Jaeschke
openaire +2 more sources
Liver Research, 2021 Background and aims: Anti-neoplastic immunotherapy has revolutionized cancer management; however, its safety profile with respect to liver-related injury remains largely unexplored.
Simcha Weissman +6 more
doaj +1 more source
Papaverine and hepatotoxicity [PDF]
Postgraduate Medical Journal, 1980 Abstract Six of 14 patients receiving a sustained release papaverine preparation developed abnormal liver function tests. One patient had jaundice and another abnormal liver histology on a biopsy specimen. This is only the third report of impaired liver function following the administration of papaverine--a drug which has been used in ...
M S, Pathy, A J, Reynolds
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Nimesulide-induced hepatotoxicity: A systematic review and meta-analysis.
PLoS ONE, 2019 OBJECTIVE:This study aimed to evaluate the risk for hepatotoxicity with nimesulide, a non-steroidal anti-inflammatory drug (NSAID) available in Republic of Korea but withdrawn from the market in several countries.
Jeongyoon Kwon +3 more
doaj +1 more source
Greater Celandine hepatotoxicity: a clinical review
Annals of Hepatology, 2012 Herbal hepatotoxicity is a rare and poorly described disease because reported cases are mostly scattered and lack an appropriate causality assessment.
Rolf Teschke, M.D. +4 more
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