Results 21 to 30 of about 201,064 (349)

United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts

open access: yesToxicology Reports, 2020
As part of the United States Pharmacopeia’s ongoing review of dietary supplement safety data, a new comprehensive systematic review on green tea extracts (GTE) has been completed.
Hellen A. Oketch-Rabah   +25 more
doaj   +1 more source

Antidepressants- and antipsychotics-induced hepatotoxicity

open access: yesArchives of Toxicology, 2021
Drug-induced liver injury (DILI) is a serious health burden. It has diverse clinical presentations that can escalate to acute liver failure. The worldwide increase in the use of psychotropic drugs, their long-term use on a daily basis, common ...
N. Todorović Vukotić   +4 more
semanticscholar   +1 more source

Metabolism and Hepatotoxicity of Pyrazinamide, an Antituberculosis Drug

open access: yesDrug Metabolism And Disposition, 2021
Pyrazinamide (PZA) is an important component of a standard combination therapy against tuberculosis. However, PZA is hepatotoxic, and the underlying mechanisms are poorly understood.
Zahir Hussain, Junjie Zhu, Xiaochao Ma
semanticscholar   +1 more source

Hepatotoxicity during Treatment for Tuberculosis in People Living with HIV/AIDS. [PDF]

open access: yesPLoS ONE, 2016
Hepatotoxicity is frequently reported as an adverse reaction during the treatment of tuberculosis. The aim of this study was to determine the incidence of hepatotoxicity and to identify predictive factors for developing hepatotoxicity after people living
Carolline Araújo-Mariz   +8 more
doaj   +1 more source

Successful Treatment with Lorlatinib after the Development of Alectinib-Induced Liver Damage in ALK-Positive Non-Small-Cell Lung Cancer: A Case Report

open access: yesCase Reports in Oncology, 2021
Alectinib is a key drug for treating anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer (NSCLC). Alectinib-induced hepatotoxicity is less common than that through other ALK inhibitors, such as crizotinib or ceritinib.
Go Makimoto   +4 more
doaj   +1 more source

Alleviation of cisplatin‐induced hepatotoxicity by gliclazide: Involvement of oxidative stress and caspase‐3 activity

open access: yesPharmacology Research & Perspectives, 2021
Cisplatin (CP), as an effective alkylating agent, is widely used in cancer treatment, while hepatotoxicity is one of its side effects. Gliclazide (GLZ), as an oral hypoglycemic drug, has antioxidant and anti‐inflammatory properties.
F. Taghizadeh   +5 more
semanticscholar   +1 more source

Navigating liver cancer with mouse models: a comprehensive overview of HCC experimental systems [PDF]

open access: yesJournal of Liver Cancer
Hepatocellular carcinoma (HCC) is the most prevalent primary hepatic malignancy and is globally the third leading cause of cancerrelated deaths. Despite significant advancements in diagnostic techniques and therapeutic interventions, HCC prognosis ...
Ga-Young Kim   +4 more
doaj   +1 more source

Studies on hepatotoxicity induced by chlorinated hydrocarbons. Lipid and ATP metabolisms in the liver of mice exposed to 1,1,2,2-tetrachloroethane [PDF]

open access: yes, 1969
With a constant gas-exposure chamber newly devised, the author had Cb mice (females weighing 16.0 ± 1.5 g) inhale 600 ppm (in average) of 1, 1, 2, 2-tetrachloroethane for 3 hours.
Tomokuni, Katsumaro
core   +1 more source

Assessment of Risk Factors of Hepatotoxicity among Tuberculosis Patients

open access: yesPharmacology and Clinical Pharmacy Research, 2018
Tuberculosis is a devastating disease caused by Mycobacterium tuberculosis. If left untreated or not properly treated, it could lead to progressive tissue damage and even death. Short-term chemotherapy containing isoniazid, rifampicin.
Muhammad F. Wardhana   +2 more
doaj   +1 more source

Proportion and Factors that Associate with Incidence of Hepatotoxicity in Rheumatoid Arthritis Patients Treated with Methotrexate in RSCM Year 2013-2015

open access: yesIndonesian Journal of Rheumatology, 2018
Background Rheumatoid arhtirtis (RA) is a chronic autoimmune disease that mainly attacks joints. It may causes joint deformities which leads to lower quality of life of RA patients.
Rahma Anindya Prathitasari   +1 more
doaj   +1 more source

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