Results 31 to 40 of about 104,266 (306)
Comparison of human hepatoma HepaRG cells with human and rat hepatocytes in uptake transport assays in order to predict drug induced hepatotoxicity [PDF]
, 2013 Human hepatocytes are the gold standard for toxicological studies but they have several drawbacks, like scarce availability, high inter-individual variability, a short lifetime, which limits their applicability.
Jemnitz, Katalin +9 more
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Does hepatotoxicity interfere with endocrine activity in zebrafish (Danio rerio)? [PDF]
, 2020 Vitellogenin (VTG), a well-established biomarker for the diagnosis of endocrine activity in fish, is used in multiple OECD test guidelines (TG) to identify activities of chemicals on hormonal pathways.
Baumann, Lisa +9 more
core +1 more source
HIV/AIDS: Research and Palliative Care, 2021 Gebremedhin Gebremicael, Habteyes Hailu Tola, Atsbeha Gebreegziaxier, Desta Kassa HIV and TB Diseases Research Directorate, Ethiopian Public Health Institute (EPHI), Addis Ababa, EthiopiaCorrespondence: Gebremedhin GebremicaelEthiopian Public Health ...
Gebremicael G +3 more
doaj
Silymarin nanoparticle prevents paracetamol-induced hepatotoxicity [PDF]
, 2011 Suvadra Das, Partha Roy, Runa Ghosh Auddy, Arup MukherjeeDepartment of Chemical Technology, University of Calcutta, Kolkata, West Bengal, IndiaAbstract: Silymarin (Sm) is a polyphenolic component extracted from Silybum marianum.
Auddy RG +7 more
core +1 more source
Safety of long-term isoniazid preventive therapy in children with HIV [PDF]
, 2014 Includes bibliographical references.Tuberculosis (TB) and HIV co-infection is association with significant morbidity and mortality, especially in young children.
Le Roux, Stanzi Maria
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Acetaminophen Hepatotoxicity [PDF]
Seminars in Liver Disease, 2019 AbstractAcetaminophen (APAP) is one of the most popular and safe pain medications worldwide. However, due to its wide availability, it is frequently implicated in intentional or unintentional overdoses where it can cause severe liver injury and even acute liver failure (ALF).
Anup, Ramachandran, Hartmut, Jaeschke
openaire +2 more sources
Studies on hepatotoxicity induced by chlorinated hydrocarbons. II. Lipid metabolism and absorption spectrum of microsomal lipid in the mice exposed to 1, 1, 2, 2-tetrachloroethane [PDF]
, 1970 Female Cb mice weighing 20-23 g were exposed to 800 ppm (in average) of 1, I, 2, 2.tetrachloroethane for 3 hours. Both triglyceride and phospholipid in the liver and plasma were determined at varying times after the exposure.
Tomokuni, Katsumaro
core +1 more source
PLoS Neglected Tropical Diseases, 2017 IntroductionLittle is known about hepatotoxicity in patients with schistosome and HIV co-infections. Several studies have reported increased liver enzymes and bilirubin levels associated with schistosome infection.
Amon I Marti +8 more
doaj +1 more source
Papaverine and hepatotoxicity [PDF]
Postgraduate Medical Journal, 1980 Abstract Six of 14 patients receiving a sustained release papaverine preparation developed abnormal liver function tests. One patient had jaundice and another abnormal liver histology on a biopsy specimen. This is only the third report of impaired liver function following the administration of papaverine--a drug which has been used in ...
M S, Pathy, A J, Reynolds
openaire +2 more sources
Risk factors for erlotinib-induced hepatotoxicity: a retrospective follow-up study
BMC Cancer, 2018 Background Erlotinib is a drug used for the treatment of non-small cell lung cancer (NSCLC) and pancreatic cancer. Severe hepatotoxicity was observed in 4% to 31% of patients receiving erlotinib treatment prompting delay or termination of treatment. Only
Min Kyoung Kim +5 more
doaj +1 more source