Hepatitis induced by noni juice from Morinda citrifolia: A rare cause of hepatotoxicity or the tip of the iceberg? [PDF]
, 2006 A 24-year-old female patient presented to her community hospital with mild elevations of serum transaminase and bilirubin levels. Because of multiple sclerosis, she was treated with interferon beta-la for 6 weeks.
Diebold, J. +3 more
core +1 more source
Anti-tuberculosis drug induced hepatotoxicity among TB/HIV co-infected patients at Jimma University Hospital, Ethiopia: nested case-control study. [PDF]
PLoS ONE, 2013 This study was carried out to determine the incidence and predictors of anti-tuberculosis drug induced hepatotoxicity among TB/HIV co-infected patients at Jimma University Hospital, Ethiopia.A nested case-control study was conducted by reviewing charts ...
Alima Hassen Ali +3 more
doaj +1 more source
Molecules, 2022 Fraxinellone (FRA), a major active component from Cortex Dictamni, produces hepatotoxicity via the metabolization of furan rings by CYP450. However, the mechanism underlying the hepatotoxicity of FRA remains unclear.
Shuting Wang +11 more
doaj +1 more source
Studies on hepatotoxicity induced by chlorinated hydrocarbons. II. Lipid metabolism and absorption spectrum of microsomal lipid in the mice exposed to 1, 1, 2, 2-tetrachloroethane [PDF]
, 1970 Female Cb mice weighing 20-23 g were exposed to 800 ppm (in average) of 1, I, 2, 2.tetrachloroethane for 3 hours. Both triglyceride and phospholipid in the liver and plasma were determined at varying times after the exposure.
Tomokuni, Katsumaro
core +1 more source
Journal of the American Chemical Society, 2019 Near-infrared (NIR) fluorescence imaging technique is garnering increasing research attention due to various advantages. However, most NIR fluorescent probes still suffer from a false signals problem owing to their instability in real application ...
Dan Cheng +7 more
semanticscholar +1 more source
Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition [PDF]
, 2018 The bile salt export pump (BSEP) is expressed at the canalicular domain of hepatocytes, where it mediates the elimination of monovalent bile salts into the bile.
Chen, Yuan +5 more
core +1 more source
HIV/AIDS: Research and Palliative Care, 2021 Gebremedhin Gebremicael, Habteyes Hailu Tola, Atsbeha Gebreegziaxier, Desta Kassa HIV and TB Diseases Research Directorate, Ethiopian Public Health Institute (EPHI), Addis Ababa, EthiopiaCorrespondence: Gebremedhin GebremicaelEthiopian Public Health ...
Gebremicael G +3 more
doaj
Dose-related liver injury of Geniposide associated with the alteration in bile acid synthesis and transportation. [PDF]
, 2017 Fructus Gardenia (FG), containing the major active constituent Geniposide, is widely used in China for medicinal purposes. Currently, clinical reports of FG toxicity have not been published, however, animal studies have shown FG or Geniposide can cause ...
Feng, Xiaoyi +17 more
core +2 more sources
Cytoprotective effects of melatonin against amitriptyline-induced toxicity in isolated rat hepatocytes [PDF]
, 2015 Purpose: Amitriptyline, one of the commonly used tricyclic antidepressants, caused rare but severe hepatotoxicity in patients who received it continuously. Previous findings showed that the intermediate metabolites of amitriptyline produced by CYP450 are
Dastmalchi, S. +3 more
core +1 more source
PLoS Neglected Tropical Diseases, 2017 IntroductionLittle is known about hepatotoxicity in patients with schistosome and HIV co-infections. Several studies have reported increased liver enzymes and bilirubin levels associated with schistosome infection.
Amon I Marti +8 more
doaj +1 more source