Results 41 to 50 of about 79,483 (168)

Drug-induced hepatotoxicity among TB/HIV co-infected patients in a referral hospital, Ethiopia

BMC Research Notes, 2020
Objectives Anti-tuberculosis drug-induced hepatotoxicity is a common serious adverse drug reaction. This study intended to determine the prevalence and associated factors of drug-induced hepatotoxicity among tuberculosis and human immunodeficiency virus ...
Abebe Zeleke, Bethelihem Misiker, Teshager Aklilu Yesuf   +2 more
doaj   +1 more source

Incidence of Severe Hepatotoxicity Related to Antiretroviral Therapy in HIV/HCV Coinfected Patients

AIDS Research and Treatment, 2010
Introduction. Hepatotoxicity is a concern in HIV/hepatitis C virus (HCV) coinfected patients due to their underlying liver disease. This study assessed the incidence of hepatotoxicity in HIV/HCV co-infected patients in two outpatient infectious diseases ...
Emily L. Heil, Mary L. Townsend, Kenneth Shipp, Amy Clarke, Melissa D. Johnson   +4 more
doaj   +1 more source

Herbal hepatotoxicity and WHO global introspection method

Annals of Hepatology, 2013
Herbal hepatotoxicity is a rare but highly disputed disease because numerous confounding variables may complicate accurate causality assessment. Case evaluation is even more difficult when the WHO global introspection method (WHO method) is applied as ...
Rolf Teschke, M.D., Axel Eickhoff, Albrecht Wolff, Christian Frenzel, Johannes Schulze   +4 more
doaj   +1 more source

Incidence of hepatotoxicity of highly active Antiretroviral Therapy in a Tertiary Health Centre in Nigeria.

Nigerian Postgraduate Medical Journal, 2012
Aims and objectives: The aim of this study was to determine the incidence of hepatotoxicity of HAART in HIV infected patients in a tertiary health centre in Nigeria.
R A Ugiagbe, A O Malu, B J Bojuwoye, A N Onunu   +3 more
doaj  

Real-world pharmacovigilance assessment of hepatotoxicity risk with HER2-Targeted drugs using FAERS database analysis

Scientific Reports
Human epidermal growth factor receptor 2 (HER2)-targeted therapies, including monoclonal antibodies (mAbs), small-molecule tyrosine kinase inhibitors (TKIs), and antibody-drug conjugates (ADCs), have significantly improved clinical outcomes in HER2 ...
Junli Dong, Dan Chen, Minyu Zhong, Guangyi Yu   +3 more
doaj   +1 more source

A computational framework for multi-scale data fusion in assessing the associations between micro- and nanoplastics and human hepatotoxicity

Environment International
Micro- and nanoplastics (MNPs) are increasingly recognized as novel environmental pollutants given their potential risks to ecosystems and human health. The liver, a vital organ for maintaining systemic homeostasis, exhibits heightened susceptibility to ...
Qiyue Wang, Dongquan Li, Ruining Guan, Yawei Wang, Hongyu Li, Chunyan Zhao   +5 more
doaj   +1 more source

Amiodarone Hepatotoxicity [PDF]

Digestive Diseases, 2008
S A, Josephson, E R, Kessel
openaire   +2 more sources

Real-world evidence of ribociclib-induced hepatotoxicity in patients with breast cancer: a multi-center experience

BMC Cancer
Background CDK4/6 inhibitors are primarily used to treat hormone-positive HER-2 negative (HR+/ HER2-) metastatic breast cancer. Although ribociclib is generally well-tolerated, there is limited real-world data on hepatotoxicity associated with its use ...
Onur Baş, Bediz Kurt İnci, İmdat Eroğlu, Safa Can Efil, Seher Kaya, Pınar Kubilay Tolunay, Taha Koray Şahin, Cengiz Karaçin, Ozan Yazıcı, Mehmet Ali Nahit Şendur, Berna Ömür Çakmak Öksüzoğlu, Sercan Aksoy   +11 more
doaj   +1 more source

Is Enflurane Hepatotoxic?

Anesthesia & Analgesia, 1986
We evaluated 88 cases of hepatic injury that followed, and were attributed to, enflurane anesthesia. In 30 of the cases, data were insufficient to assess the role of enflurane vs other variables as causal factors. In 43 ("unlikely") patients, factors known to produce hepatic injury were clearly present; in the remaining 15 ("possible"), such factors ...
E I, Eger, E A, Smuckler, L D, Ferrell, C H, Goldsmith, B H, Johnson   +4 more
openaire   +3 more sources

Risk factors for irinotecan-induced hepatotoxicity: a retrospective cohort study

Frontiers in Oncology
BackgroundIrinotecan is a potent chemotherapeutic agent used as a neoadjuvant in colorectal cancer liver metastasis and significantly enhances five-year survival rates. Recently, irinotecan-associated hepatotoxicity was a significant concern.
Fatemah A. Alherz, Anwar M. Alnakhli, Aisha M. Alqarni, Alanoud F. Alshammari, Alhanouf M. Ruwayi, Rahaf M. Alyamani, Haya Al-salloum, Mohammad J. Al-Yamani, Farag Shuweihdi   +8 more
doaj   +1 more source