Results 11 to 20 of about 79,419 (267)

Hepatotoxicity of botanicals [PDF]

Public Health Nutrition, 2000
AbstractObjectiveHepatic impairment resulting from the use of conventional drugs is widely acknowledged, but there is less awareness of the potential hepatotoxicity of herbal preparations and other botanicals, many of which are believed to be harmless and are commonly used for self-medication without supervision. The aim of this paper is to examine the
F, Stickel, G, Egerer, H K, Seitz
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Evaluation of factors affecting epidermal growth factor receptor tyrosine kinase inhibitor-induced hepatotoxicity in Japanese patients with non-small cell lung cancer: a two-center retrospective study

Journal of Pharmaceutical Health Care and Sciences, 2022
Background Gefitinib and erlotinib, are epidermal growth factor receptor tyrosine kinase inhibitors, and are currently recommended for non-small cell lung cancer stage IV in the elderly and in patients with decreased performance status in the Japanese ...
Hirofumi Nagai, Tsutomu Shimada, Yoshimitsu Takahashi, Mikako Nishikawa, Hiroyuki Tozuka, Yasuto Yamamoto, Osamu Niwa, Yutaka Takahara, Arimi Fujita, Katsuhiko Nagase, Kazuo Kasahara, Seiji Yano, Yoshimichi Sai   +12 more
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Proportion and Factors that Associate with Incidence of Hepatotoxicity in Rheumatoid Arthritis Patients Treated with Methotrexate in RSCM Year 2013-2015

Indonesian Journal of Rheumatology, 2018
Background Rheumatoid arhtirtis (RA) is a chronic autoimmune disease that mainly attacks joints. It may causes joint deformities which leads to lower quality of life of RA patients.
Rahma Anindya Prathitasari, Harry Isbagio   +1 more
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Risk factors of severe hepatotoxicity among HIV-1 infected individuals initiated on highly active antiretroviral therapy in the Northwest Region of Cameroon

BMC Gastroenterology, 2022
Background Hepatotoxicity due to highly active antiretroviral therapy (HAART) has gained prominent attention since it can be affected by many factors.
Lem Edith Abongwa, Anthony Kebira Nyamache, Fokunang Charles, Judith Torimiro, Nshom Emmanuel, Irénée Domkam, Mbu Eyongetah, Beriyuy Jude, Fung Holgar Mua, Sama Bella, Tankou Colman Tamboh, Erna Charlene Moungang, Victorine Ngum, Paul Okemo   +13 more
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Application of iTRAQ-Based Quantitative Proteomics Approach to Identify Deregulated Proteins Associated with Liver Toxicity Induced by Polygonum Multiflorum in Rats

Cellular Physiology and Biochemistry, 2017
Background/Aims: Clinical reports on adverse reactions that result from Polygonum multiflorum (PM) and its preparations, especially regarding liver injury, have recently received widespread attention.
Longfei Lin, Hui Li, Hongmei Lin, Miao Zhang, Changhai Qu, Lei Yan, Xingbin Yin, Jian Ni   +7 more
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Hepatotoxicity of immune checkpoint inhibitors: a Bayesian network meta-analysis

Hepatology Communications, 2023
Background:. This systematic review and network meta-analysis aimed to provide a complete hepatotoxicity profile, hepatotoxicity spectrum, and safety ranking of immune checkpoint inhibitor drugs for cancer treatment. Methods:.
Caiyun Zheng, Shunmin Huang, Meimei Lin, Baohui Hong, Ruping Ni, Hengfen Dai, Xiuqin Lin, Jing Yang   +7 more
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Anti-tuberculosis drug induced hepatotoxicity among TB/HIV co-infected patients at Jimma University Hospital, Ethiopia: nested case-control study. [PDF]

PLoS ONE, 2013
This study was carried out to determine the incidence and predictors of anti-tuberculosis drug induced hepatotoxicity among TB/HIV co-infected patients at Jimma University Hospital, Ethiopia.A nested case-control study was conducted by reviewing charts ...
Alima Hassen Ali, Tefera Belachew, Alemeshet Yami, Wubeante Yenet Ayen   +3 more
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Fraxinellone Induces Hepatotoxicity in Zebrafish through Oxidative Stress and the Transporters Pathway

Molecules, 2022
Fraxinellone (FRA), a major active component from Cortex Dictamni, produces hepatotoxicity via the metabolization of furan rings by CYP450. However, the mechanism underlying the hepatotoxicity of FRA remains unclear.
Shuting Wang, Jie Bao, Jie Li, Wanfang Li, Mengyin Tian, Caixia Qiu, Fei Pang, Xin Li, Jianbo Yang, Yuchi Hu, Sujuan Wang, Hongtao Jin   +11 more
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Incidence of Hepatotoxicity and Factors Associated During Highly Active Antiretroviral Therapy in People Living with HIV in Ethiopia: A Prospective Cohort Study

HIV/AIDS: Research and Palliative Care, 2021
Gebremedhin Gebremicael, Habteyes Hailu Tola, Atsbeha Gebreegziaxier, Desta Kassa HIV and TB Diseases Research Directorate, Ethiopian Public Health Institute (EPHI), Addis Ababa, EthiopiaCorrespondence: Gebremedhin GebremicaelEthiopian Public Health ...
Gebremicael G, Tola HH, Gebreegziaxier A, Kassa D   +3 more
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Acetaminophen Hepatotoxicity [PDF]

Seminars in Liver Disease, 2019
AbstractAcetaminophen (APAP) is one of the most popular and safe pain medications worldwide. However, due to its wide availability, it is frequently implicated in intentional or unintentional overdoses where it can cause severe liver injury and even acute liver failure (ALF).
Anup, Ramachandran, Hartmut, Jaeschke
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