Nevirapine-associated early hepatotoxicity: incidence, risk factors, and associated mortality in a primary care ART programme in South Africa. [PDF]
PLoS ONE, 2010 BackgroundThe majority of antiretroviral treatment programmes in sub-Saharan Africa are scaling up antiretroviral treatment using a fixed dose first-line antiretroviral regimen containing stavudine, lamivudine, and nevirapine. One of the primary concerns
Kathryn M Chu +5 more
doaj +2 more sources
Greater Celandine hepatotoxicity: a clinical review
Annals of Hepatology, 2012 Herbal hepatotoxicity is a rare and poorly described disease because reported cases are mostly scattered and lack an appropriate causality assessment.
Rolf Teschke, M.D. +4 more
doaj +3 more sources
Herbal hepatotoxicity and WHO global introspection method
Annals of Hepatology, 2013 Herbal hepatotoxicity is a rare but highly disputed disease because numerous confounding variables may complicate accurate causality assessment. Case evaluation is even more difficult when the WHO global introspection method (WHO method) is applied as ...
Rolf Teschke, M.D. +4 more
doaj +3 more sources
Suplementary material: Towards uncoding hepatotoxicity of approved drugs through navigation of multiverse and consensus chemical spaces [PDF]
, 2022 Supplementary material: "Towards uncoding hepatotoxicity of approved drugs through navigation of multiverse and consensus chemical ...
Edgar, López-López +3 more
core +1 more source
, 2022 The hepatotoxicity of cadmium-based quantum dots (Cd-QDs) has become the focus with their extensive applications in biomedicine. Previous reports have demonstrated that high oxidative stress and consequent redox imbalance play critical roles in their ...
Wen Gao +13 more
core +1 more source
Hepatotoxicity of botanicals [PDF]
Public Health Nutrition, 2000 AbstractObjectiveHepatic impairment resulting from the use of conventional drugs is widely acknowledged, but there is less awareness of the potential hepatotoxicity of herbal preparations and other botanicals, many of which are believed to be harmless and are commonly used for self-medication without supervision. The aim of this paper is to examine the
F, Stickel, G, Egerer, H K, Seitz
openaire +2 more sources
Drug interactions and hepatotoxicity of clopidogrel [PDF]
, 2010 Clopidogrel (Plavix¨) is an antiplatelet drug, which is clinically used in combination with aspirin to reduce cardiovascular events in patients undergoing percutaneous coronary intervention or in patients suffering from acute coronary syndromes ...
Zahno, Anja-Christina
core +1 more source
Studies on hepatotoxicity induced by chlorinated hydrocarbons. Lipid and ATP metabolisms in the liver of mice exposed to 1,1,2,2-tetrachloroethane [PDF]
, 1969 With a constant gas-exposure chamber newly devised, the author had Cb mice (females weighing 16.0 ± 1.5 g) inhale 600 ppm (in average) of 1, 1, 2, 2-tetrachloroethane for 3 hours.
Tomokuni, Katsumaro
core +1 more source
Hepatotoxicity of the phytomedicines Kava Kava and Cimicifuga Racemosa [PDF]
, 2005 In this thesis the hepatotoxic properties of the two phytomedicines kava kava and cimicifuga racemosa have been investigated. This topic is a prevailing problem as herbal medicines are quite popular today and not much is known about their toxicological
Lüde, Saskia
core +1 more source
The incidence of liver injury in Uyghur patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, cyp2e1, gstm1 and gstt1. [PDF]
, 2014 BACKGROUND AND OBJECTIVE: Of three first-line anti-tuberculosis (anti-TB) drugs, isoniazid is most commonly associated with hepatotoxicity. Differences in INH-induced toxicity have been attributed to genetic variability at several loci, NAT2, CYP2E1 ...
Ma, Jinfeng +50 more
core +1 more source