Results 11 to 20 of about 63,484 (304)

A Hepatocyte-to-Stellate Cell Axis Couples Alternate-Day Fasting to Liver Fibrosis Resolution via ATG7 S-Nitrosylation. [PDF]

Adv Sci (Weinh)
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Wang X, Zeng M, Sun C, Gou Y, Feng Z, Lv W, Yan C, Wu H, Zhang P, Xu J, Cao K, Li H, Ding M, Liu Z, Zhang X, Liu J, Zou X, Feng Z.   +17 more
europepmc   +2 more sources

Combining Experimental and DFT Investigation of the Mechanism Involved in Thermal Etching of Titanium Nitride Using Alternate Exposures of NbF5 and CCl4, or CCl4 Only [PDF]

, 2021
Funding Information: The authors thank Eurofins EAG Materials Science, LLC (California, USA) for the TEM analysis. S.K.N. thanks ICHEC and the Science Foundation Ireland funded computing center of Tyndall National Institute for computer time.
Marko Tuominen, Tom Blomberg, Elliott, Simon D., Tuominen, Marko, Blomberg, Tom, Haukka, Suvi, Givens, Michael E., Suresh Kondati Natarajan, Michael E. Givens, Ritala, Mikko, Varun Sharma, Mikko Ritala, Sharma, Varun, Kondati Natarajan, Suresh, Simon D. Elliott, Natarajan, Suresh Kondati, Suvi Haukka   +16 more
core   +1 more source

The pharmacological effect of apricot seeds extracts and amygdalin in experimentally induced liver damage and hepatocellular carcinoma [PDF]

Journal of HerbMed Pharmacology, 2020
Introduction: Apricot (Prunus armeniaca L.) has been widely used for the treatment of several disorders such as liver diseases, but the hepatoprotective and anticancer activities of its seeds were not studied before.
Amer Ramadan, Gehan Kamel, Nagwa E. Awad, Aya A. Shokry, Hany M Fayed   +4 more
doaj   +1 more source

Investigation on Chlorination of Uranium Oxides With CCl4 and HCl Gas

He huaxue yu fangshe huaxue, 2022
In this study, the chlorination mechanism and influencing factors of uranium oxides(mainly U3O8) were studied by using CCl4 and HCl gas as chlorination reagents respectively. The chlorination of U3O8 powder was studied with CCl4 as chlorination reagent.
MENG Zhao-kai, LIN Ru-shan, CHEN Hui, SONG Wen-chen, ZHANG Jin-yu, YAO Ben-lin, HE Hui, YE Guo-an   +7 more
doaj   +1 more source

The Effect of Citrullus Colocynthis on Serum Lipid Profile and Hepatic Histology in CCl 4-Induced Liver Injury Rat Model [PDF]

International Journal of Nutrition Sciences, 2020
Background: Chemical drugs in treatment of liver diseases are still scare and with many complications. Citrullus colocynthis known as bitter apple is on of herbals that can affect liver function. This study evaluated the effect of C. colocynthis on serum
Mina Fouzi, Nematollah Razmi, Davood Mehrabani   +2 more
doaj   +1 more source

Transplantation of human amnion epithelial cells reduces hepatic fibrosis in immunocompetent CCl4-treated mice [PDF]

, 2010
Chronic liver injury and inflammation lead to hepatic fibrosis, cirrhosis, and liver failure. Embryonic and\ud mesenchymal stem cells have been shown to reduce experimental liver fibrosis but have potential limitations,\ud including the formation of ...
William Sievert, Williams, Elizabeth D., Manuelpillai, Ursula, Lourensz, Dinushka, Vijesh Vaghjiani, Tchongue, Jorge, Jorge Tchongue, Sievert, William, Liu, Alison, Ursula Manuelpillai, Dinushka Lourensz, Alison Liu, Elizabeth D. Williams, Vaghjiani, Vijesh, Chrishan S. Samuel, Samuel, Chrishan S.   +15 more
core   +1 more source

Hepatoprotective Effect of Sun Chlorella as an Antioxidant in Rattus norvegicus Induced Carbon Tetrachloride

Global Medical & Health Communication, 2021
Carbon tetrachloride (CCl₄) is a chemical that can cause damage to liver cells. One of the natural ingredients developed to reduce liver damage due to chemicals and infections is Chlorella sp.
Wahyu Siswandari, Fitranto Arjadi, Hernayanti Hernayanti, Vitasari Indriani   +3 more
doaj   +1 more source

Nos2 deficiency enhances carbon tetrachloride-induced liver injury in aged mice [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): As a multifunctional molecule, NO has different effects on liver injury. The present work aimed to investigate the effects of Nos2 knockout (KO) on acute liver injury in aged mice treated with carbon tetrachloride (CCl4).
Deming Li, Yaping Song, Yahao Wang, Yuedong Guo, Zhaoke Zhang, Ganggang Yang, Gaiping Wang, Cunshuan Xu   +7 more
doaj   +1 more source

Genome-wide DNA methylation dynamics in carbon tetrachloride-induced mice liver fibrosis [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): Many persistent harmful stimuli can result in chronic liver diseases, which lead to about 2 million deaths per year in the whole world. Liver fibrosis was found to exist in all kinds of chronic liver diseases.
Deming Li, Xiaoshu Guo, Wenyu Zhao, Jingyu Chen, Cong Xia, Guoying Yu   +5 more
doaj   +1 more source

Assessment of Nanosilymarin's Therapeutic Efficacy in Mitigating CCl4-Induced Hepatotoxicity in Rats [PDF]

Basrah Journal of Veterinary Research
Drug and chemical substances are common causes of liver dysfunction, including acute hepatitis and liver failure. Carbon tetrachloride (CCl4) is widely used as a model to study hepatic toxicity.
Nisreen Jasim
doaj   +1 more source