Heparanase and macrophage interplay in the onset of liver fibrosis [PDF]
, 2017 The heparan sulfate endoglycosidase heparanase (HPSE) is involved in tumor growth, chronic inflammation and fibrosis. Since a role for HPSE in chronic liver disease has not been demonstrated to date, the current study was aimed at investigating the ...
Crescenzi, Marika +5 more
core +2 more sources
Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles. [PDF]
, 2020 Alcoholic liver disease (ALD) is a leading cause of cirrhosis in the United States, which is characterized by extensive deposition of extracellular matrix proteins and formation of a fibrous scar.
Baglieri, Jacopo +16 more
core +1 more source
Assessment of Nanosilymarin's Therapeutic Efficacy in Mitigating CCl4-Induced Hepatotoxicity in Rats [PDF]
Basrah Journal of Veterinary ResearchDrug and chemical substances are common causes of liver dysfunction, including acute hepatitis and liver failure. Carbon tetrachloride (CCl4) is widely used as a model to study hepatic toxicity.
Nisreen Jasim
doaj +1 more source
Anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda incrassata (Chlorophyta, Bryopsidales) [PDF]
, 2017 Seaweeds are a source of natural antioxidants having potential application in oxidative stress and associated diseases. In this work, anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda ...
Claudina, Zaldívar-Munoz +8 more
core +1 more source
Dynamic heterogeneity in the glass-like monoclinic phases of some halogen methane compounds [PDF]
, 2013 In this work we study the heterogeneity of the dynamics on the low-temperature monoclinic phases of the simple molecular glassy systems CBrnCl4−nCBrnCl4−n, n = 0, 1, 2.
Pardo, L. C. +3 more
core +1 more source
Protective Effect of Silybin in Rats Liver Toxicity
Scientific Papers Animal Science and Biotechnologies, 2023 Silybin is a flavonoid extracted from the herb Armurariu (Silybum marianum) and has the potential efficacy in the treatment of liver disease. The aims of this study were to investigate the effect of alcohol and CCl4 on liver histology and the capacity of
Roxana Popescu +3 more
doaj
Hepatoprotective effects of Artemia salina L. extract against carbon tetrachloride-induced toxicity [PDF]
Trends in Pharmaceutical Sciences, 2016 The protective effects of Artemia salina L. extract was examined against carbon tetrachloride (CCl4)-induced cell toxicity. In the in vitro model of study, markers such as cell viability, cellular reduced and oxidized glutathione, and lipid peroxidation ...
Mohammad Ali Mobasher +4 more
doaj
Effects of MgCl2 supplementation on blood parameters and kidney injury of rats exposed to CCl4
Open Life Sciences, 2016 The purpose of this study was to evaluate the beneficial effects of magnesium (Mg) supplementation upon carbon tetrachloride (CCl4) toxicity. Our study was carried out on 24 Wistar male rats divided into 4 batches.
Mbarki Sakhria +4 more
doaj +1 more source
MRI Tracking of Macrophages Labeled with Glucan Particles Entrapping a Water Insoluble Paramagnetic Gd-Based Agent. [PDF]
, 2012 PURPOSE: This study is aimed at demonstrating the in vivo potential of Gd(III)-loaded glucan particles (Gd-GPs) as magnetic resonance imaging (MRI)-positive agents for labeling and tracking phagocytic cells.
Aime, Silvio +7 more
core +1 more source
The pharmacological effect of apricot seeds extracts and amygdalin in experimentally induced liver damage and hepatocellular carcinoma [PDF]
Journal of HerbMed Pharmacology, 2020 Introduction: Apricot (Prunus armeniaca L.) has been widely used for the treatment of several disorders such as liver diseases, but the hepatoprotective and anticancer activities of its seeds were not studied before.
Amer Ramadan +4 more
doaj +1 more source