Results 261 to 270 of about 300,891 (314)

Oxymatrine Inhibits Epithelial‐Mesenchymal Transition to Alleviate Airway Remodeling in Chronic Obstructive Pulmonary Disease by Suppressing the TGF‐β1/Smad Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explored the therapeutic efficacy of oxymatrine (OMT, C15H24N2O2) in a murine model of cigarette smoke (CS)‐induced chronic obstructive pulmonary disease (COPD) and elucidated its underlying mechanisms. A COPD model was established in mice through prolonged exposure to CS, followed by intraperitoneal administration of OMT (50 mg/kg)
Shuang Zhou, Ju‐Xiang Zhu, Jing Li
wiley   +1 more source

Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang   +5 more
wiley   +1 more source

Cost‐Utility Analysis of Intracapsular and Extracapsular Techniques for Pediatric Tonsillectomy

open access: yesThe Laryngoscope, EarlyView.
Intracapsular coblation tonsillectomy (ICT) is more cost‐effective than extracapsular tonsillectomy (ECT) in pediatric patients, particularly for ambulatory procedures. In a prospective cohort of over 5000 cases, ICT was associated with lower costs and comparable or better quality‐adjusted life years, even when accounting for potential revision ...
Stephen R. Chorney   +2 more
wiley   +1 more source

Adenotonsillar Microbiome Shifts in Children With Obstructive Sleep Apnea Syndrome

open access: yesThe Laryngoscope, EarlyView.
This study compares the microbiomes of adenoids and tonsils in pediatric OSAS patients and healthy controls using 16S rRNA sequencing. Significant differences were found in the tonsillar microbiome of OSAS patients, with lower alpha diversity and an overrepresentation of pathogenic genera like Haemophilus and Neisseria, while adenoid microbiomes showed
Oded Kraus   +7 more
wiley   +1 more source

Suction-Assisted Laryngoscopy and Airway Decontamination (SALAD) for Emergency Airway Management: A Systematic Review of Evidence and Implementation. [PDF]

open access: yesJ Clin Med
Shaikh S   +10 more
europepmc   +1 more source

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