Results 41 to 50 of about 8,840,833 (296)

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Effects of endotracheal tube and laryngeal mask airway on postoperative pulmonary complications in general anesthesia [PDF]

Jichu yixue yu linchuang
Postoperative pulmonary complications (PPCs) after general anesthesia surgery significantly affect patient prognosis. However, there′s insufficient evidence to confirm if different airway management tools influence PPCs.
PENG Yu, YI Jie
doaj   +1 more source

An international survey of airway management education in 61 countries†.

, 2021
BACKGROUND:Deficiencies in airway management skills and judgement contribute to poor outcomes. Airway management practice guidelines emphasise the importance of education.
Critchley, Julia, Harding, Fleur, Myatra, Sheila N, McNarry, Alistair F, World Airway Management Meeting 2015 Education Group, Armstrong, Laura, Baker, Paul A, Cooper, Richard   +7 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Advancing emergency airway management practice and research

Acute Medicine & Surgery, 2019
Emergency airway management is one of the vital resuscitative procedures undertaken in the emergency department (ED). Despite its clinical and research importance in the care of critically ill and injured patients, earlier studies have documented ...
Tadahiro Goto, Yukari Goto, Yusuke Hagiwara, Hiroshi Okamoto, Hiroko Watase, Kohei Hasegawa   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Elevated Paracellular Glucose Flux across Cystic Fibrosis Airway Epithelial Monolayers Is an Important Factor for Pseudomonas aeruginosa Growth. [PDF]

, 2013
People with cystic fibrosis (CF) who develop related diabetes (CFRD) have accelerated pulmonary decline, increased infection with antibiotic-resistant Pseudomonas aeruginosa and increased pulmonary exacerbations.
James P Garnett, Tarran Robert, Ward, Christopher, Ward Christopher, Michael A Gray, Baines, DL, Garnett, James P., Robert Tarran, Christopher Ward, Ward, C, Garnett, JP, Baker, EH, Brodlie Malcolm, Baker, Emma H., Tarran, Robert, Gray Michael A., Brodlie, Malcolm, Baker Emma H., Garnett James P., Brodlie, M, Deborah L Baines, Baines Deborah L., Gray, Michael A., Baines, Deborah L., Gray, MA, Malcolm Brodlie, Tarran, R, Emma H Baker   +27 more
core   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

Difficult airway management in a child with Treacher Collins syndrome and cleft palate

Journal of Clinical Sciences
Anaesthesia for patients with Treacher Collins syndrome (TCS) can be challenging due to their craniofacial abnormalities and potential difficult airway. TCS presents with micrognathia and retrognathia, a small oral aperture, and severe temporomandibular ...
Gabriel Kolawole Asiyanbi, Mohammed M. Jika, Adegbayi Adeola Adekunle, Nkoyo Emmanuel Enyenihi, Ijeoma Chinenye Ohagwu, Ibironke Desalu   +5 more
doaj   +1 more source

Complications of Airway Management [PDF]

Respiratory Care, 2014
Although endotracheal intubation is commonly performed in the hospital setting, it is not without risk. In this article, we review the impact of endotracheal intubation on airway injury by describing the acute and long-term sequelae of each of the most commonly injured anatomic sites along the respiratory tract, including the nasal cavity, oral cavity,
Paulette C, Pacheco-Lopez, Lauren C, Berkow, Alexander T, Hillel, Lee M, Akst   +3 more
openaire   +2 more sources