Results 171 to 180 of about 18,946 (199)

An Intraoperative EEG Biomarker for Postoperative Delirium Predicting Based on Interpretable Deep Learning Framework

open access: yesMedComm, Volume 7, Issue 9, September 2026.
An interpretable intraoperative EEG framework predicts postoperative delirium (POD) in older surgical patients. A data‐driven best temporal filter (BTF) reveals frontal sensitivity and captures a distinctive 2–12 Hz (δ–θ–α) spindle‐like target wave occurring more frequently in POD patients, enabling event‐quantifiable intraoperative monitoring and ...
Yinuo Zhang   +11 more
wiley   +1 more source

Exploring the Content Validity of Patient‐Reported Outcome Measures to Capture the Patient Experience of Becker Muscular Dystrophy

open access: yesMuscle &Nerve, Volume 74, Issue 3, Page 559-569, September 2026.
ABSTRACT Introduction/Aims The patient experience of Becker muscular dystrophy (BMD) is not well understood, making it difficult to evaluate the conceptual relevance of proposed patient‐reported outcome (PRO) measures. This study aimed to conceptualize the patient experience of BMD and evaluate content validity and perceptions of meaningful changes of ...
Abby Bronson   +6 more
wiley   +1 more source

Optimizing Research Operations and Resource Utilization in ALS Care: Insights From the Tofersen Antisense Oligonucleotide Expanded Access Protocol

open access: yesMuscle &Nerve, Volume 74, Issue 3, Page 692-697, September 2026.
ABSTRACT Introduction/Aims Tofersen is a gene‐targeted therapy for individuals with superoxide dismutase 1 (SOD1) (+) amyotrophic lateral sclerosis (ALS). Prior to U.S. Food and Drug Administration (FDA) approval, tofersen was made available through expanded access protocol.
Alison Wheeler   +30 more
wiley   +1 more source

Intraoperative Cardiac Events During Pediatric Cardiac Magnetic Resonance Imaging Under Anesthesia: A Retrospective Cohort Study

open access: yesPediatric Anesthesia, Volume 36, Issue 9, Page 1143-1152, September 2026.
ABSTRACT Background Children with congenital heart disease (CHD) frequently undergo cardiac magnetic resonance imaging (MRI) under anesthesia. Although these procedures lack surgical stimulus, patients remain physiologically vulnerable, and the incidence of perioperative cardiovascular instability in this setting is poorly defined.
Theodora Wingert   +8 more
wiley   +1 more source

Pediatric Functional Lung Imaging: A Scoping Review

open access: yesPediatric Pulmonology, Volume 61, Issue 9, September 2026.
ABSTRACT Functional lung imaging enables pulmonary parameters, including ventilation, perfusion, gas exchange, and biomechanics, to be mapped and quantified noninvasively throughout the lungs. Pulmonary function testing is generally more difficult to perform in a child in comparison to an adult, and so pulmonary functional imaging has the potential to ...
Matthew Bruorton   +9 more
wiley   +1 more source

Atypical Fibrotic‐Mimicking Pulmonary Sarcoidosis in a Young Female: The Basal Conundrum

open access: yesRespirology Case Reports, Volume 14, Issue 9, September 2026.
We present a case of pulmonary sarcoidosis in a young female who had a confounding basal‐peripheral phenotype, eventually diagnosed through endobronchial biopsy showing non‐necrotizing granulomas with asteroid bodies. ABSTRACT Pulmonary sarcoidosis is a systemic inflammatory disease characterized by the formation of non‐caseating granulomas; it ...
Ali Gohar   +5 more
wiley   +1 more source

Therapeutic Strategy of Extracorporeal Carbon Dioxide Removal in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Combined With Central Airway Stricture: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 9, September 2026.
This case demonstrates that medium‐flow ECCO2R can serve as an effective bridge to therapy in AECOPD combined with central airway stricture, safely correcting refractory hypercapnia and providing a stable window for successful bronchoscopic stenting and ventilator weaning. ABSTRACT This case report highlights a novel and successful therapeutic strategy
Jingjing Deng   +3 more
wiley   +1 more source

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