Results 101 to 110 of about 2,432,490 (285)

Application of Interrupter Resistance and Spirometry Techniques in Pediatric Pulmonary Medicine: Feasibility and Concordance in Healthy Children Under 8 Years

Medicina
Background and Objectives: Pediatric pulmonary medicine relies heavily on accurate lung function assessment, yet conventional spirometry presents challenges in children due to cooperation requirements.
Rim Kammoun, Farah Gargouri, Asma Haddar, Halil İbrahim Ceylan, Valentina Stefanica, Walid Feki, Hatem Ghouili, Ismail Dergaa, Kaouthar Masmoudi   +8 more
doaj   +1 more source

Analysis of airway secretions in a model of sulfur dioxide induced chronic obstructive pulmonary disease (COPD) [PDF]

, 2006
Hypersecretion and chronic phlegm are major symptoms of chronic obstructive pulmonary disease (COPD) but animal models of COPD with a defined functional hypersecretion have not been established so far.
David A Groneberg, Wagner, Ulrich, Fischer, Axel, Groneberg, Jan David Alexander, Groneberg David A, Welte, Tobias, Fehmann Hans-Christoph, Staats Petra, Axel Fischer, Welte Tobias, Fischer Axel, Ulrich Wagner, Tobias Welte, Fehmann, Hans-Christoph, Petra Staats, Staats, Petra, Hans-Christoph Fehmann, Wagner Ulrich   +17 more
core   +1 more source

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source

Orexin-A Excites Airway Vagal Preganglionic Neurons via Activation of Orexin Receptor Type 1 and Type 2 in Rats

Frontiers in Cellular Neuroscience, 2019
Airway vagal nerves play a predominant role in the neural control of the airway, and augmented airway vagal activity is known to play important roles in the pathogenesis of some chronic inflammatory airway diseases.
Yonghua Chen, Yuhong Guo, Xianxia Yan, Ming Zeng, Hong Chen, Dongying Qiu, Jijiang Wang   +6 more
doaj   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

Precision-Controlled Bionic Lung Simulator for Dynamic Respiration Simulation

Bioengineering
Mechanical ventilation is indispensable for patients with severe respiratory conditions, and high-fidelity lung simulators play a pivotal role in ventilator testing, clinical training, and respiratory research.
Rong-Heng Zhao, Shuai Ren, Yan Shi, Mao-Lin Cai, Tao Wang, Zu-Jin Luo   +5 more
doaj   +1 more source

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

Barometric whole-body plethysmography investigating breed-specific variations in dogs

Frontiers in Veterinary Science
IntroductionBarometric whole-body plethysmography (BWBP) is a non-invasive method for pulmonary function testing in dogs. A significant advantage over other techniques is the possibility to perform measurements in awake and unrestrained animals ...
Charlotte Münch, Hannah Gareis, Simon Wiegrebe, Juliet Fleischer, Bianka Schulz   +4 more
doaj   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

The role of body plethysmography in modern respiratory diagnostics: a literature review

Сучасні медичні технології
Aim. To systematize current knowledge on the methodological principles of body plethysmography, summarize data on reference parameters, and analyze recent trends of its application in the diagnosis of respiratory diseases. Materials and methods.
Ya. M. Mykhailovskyi
doaj   +1 more source