Results 121 to 130 of about 109,154 (297)

Airway responsiveness as measured by resistance to intranasal methacholine.

open access: yes, 2014
Airway resistance curves to methacholine for (A) WT and (B) PHIL mice; (C) Maximal airway resistance in response to 25 mg/mL methacholine i.n. (n = 10 per group). Data are presented as the maximal resistance between 3.1–25 mg/mL minus the baseline value (
Roma Sehmi (589972)   +3 more
core   +1 more source

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki   +3 more
wiley   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen   +7 more
wiley   +1 more source

Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood   +6 more
wiley   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

open access: yesBiotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Exploring upper airway and laryngeal resistance to noninvasive ventilation in healthy awake adults

open access: yesPhysiological Reports
The interaction between anatomical structures, pressure, and airflow impacts the airway resistance. The airflow during noninvasive ventilation (NIV) relies on the upper airway and laryngeal patency.
Anne Kristine Brekka   +10 more
doaj   +1 more source

Airway resistance: Synonyms, surrogates, and precision

open access: yes, 2011
Airway resistance: Synonyms, surrogates, and ...
LKA Lundblad (14459700)   +4 more
core  

Assessment of Airway Resistance and Specic Airway Conductance in Centrally Obese Adults

open access: yes
<p>Background:Obesity's systemic consequences impact pulmonary function, with central obesity exerting a more signicant inuence on pulmonary mechanics than peripheral obesity.
Dr. Juno Mariam Cyril   +1 more
core   +1 more source

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