Results 301 to 310 of about 3,409,424 (392)

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

open access: yesSmall Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou   +8 more
wiley   +1 more source

220 Relevance of specific airway resistance (sRAW) in pre-school children with cystic fibrosis

open access: bronze, 2005
M. Maroli   +7 more
openalex   +1 more source

MiR‐1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT MicroRNA‐1 (miR‐1) is a conserved microRNA that is highly expressed in skeletal and cardiac muscle tissues. Moreover, miR‐1 regulates genes and has critical roles in cell migration and invasion. Downregulation of miR‐1 has been found in many pathologies of numerous organs, including the lungs.
Maricica Pacurari   +2 more
wiley   +1 more source

Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Dysphagia is a prevalent symptom of the upper gastrointestinal tract causing health related consequences, impacting quality of life and is associated with global economic burden. Swallowing difficulties are classified into oropharyngeal dysphagia (OD) and esophageal dysphagia.
Amir Mari   +45 more
wiley   +1 more source

Comparison of the effects of an endotracheal tube and a V‐gel airway device on intraocular pressure and haemodynamic responses in anaesthetised cats

open access: yesVeterinary Record, EarlyView.
Abstract Background This study aimed to compare the effects of placing an endotracheal tube (ETT) versus a V‐gel airway device on intraocular pressure (IOP), heart rate (HR), mean arterial pressure (MAP) and peripheral oxygen saturation (SpO2) in anaesthetised cats.
Mehmet Nur Cetin   +5 more
wiley   +1 more source

Profound Increase of Lung Airway Resistance in Heart Failure: a Potential Important Contributor for Dyspnea. [PDF]

open access: yesJ Cardiovasc Transl Res, 2019
Liu X   +10 more
europepmc   +1 more source

A neuromorphic system based on spiking‐timing‐dependent plasticity for evaluating wakefulness and anesthesia states using intracranial EEG signals

open access: yesVIEW, EarlyView.
Existing clinical approaches for assessing anesthesia depth often rely on physiological and behavioral indicators, which can be unreliable due to uncertain correlation with patient consciousness. This study presents a neuromorphic SNN with STDP, implemented on an field‐programmable gate array (FPGA) platform, enabling real‐time iEEG‐based assessment of
Ke Chen   +8 more
wiley   +1 more source

Unveiling large multimodal models in pulmonary CT: A comparative assessment of generative AI performance in lung cancer diagnostics

open access: yesVIEW, EarlyView.
1. The emergence of generative artificial intelligence (Gen‐AI) requires rigorous validation to assess its diagnostic reliability and limitations. 2. Three Gen‐AI models (GPT‐4‐turbo, Gemini‐pro‐vision, and Claude‐3‐opus) performed inconsistently across different diagnostic environments, demonstrating significant internal variability and overall ...
Lihaoyun Huang   +17 more
wiley   +1 more source

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