Results 71 to 80 of about 28,913 (272)

Airy transformation of Airyprime beam

Acta Physica Sinica
As a remarkable optical transformation enabling mutual conversion between Gaussian and Airy beams, the Airy transformation raises intriguing questions when applied to Airyprime beam—an advanced variant of conventional Airy beam. To answer these questions, numerical simulations and experimental verification are combined in this study.
Jiahao CHEN, Hongfei GAO, Jian HE, Fei WANG, Yimin ZHOU, Yiqing XU, Yangjian CAI, Guoquan ZHOU   +7 more
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Marginal densities of the "true" self-repelling motion [PDF]

, 2012
Let X(t) be the true self-repelling motion (TSRM) constructed by B.T. and Wendelin Werner in 1998, L(t,x) its occupation time density (local time) and H(t):=L(t,X(t)) the height of the local time profile at the actual position of the motion.
Dumaz, Laure, Tóth, Bálint
core  

Optical vortex coronagraphs on ground-based telescopes

, 2007
The optical vortex coronagraph is potentially a remarkably effective device, at least for an ideal unobstructed telescope. Most ground-based telescopes however suffer from central obscuration and also have to operate through the aberrations of the ...
Abramowitz, Beuzit, Dooley, Foo, Gratadour, Guyon, Guyon, Johns, Lee, Macintosh, Mawet, Palacios, Palacios, Riaud, Roddier, Rouan, Schwarzlander, Sivaramakrishnan, Soummer, Watson, Watson, Watson   +21 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The Structure of High Strehl Ratio Point-Spread Functions

, 2003
We describe the symmetries present in the point-spread function (PSF) of an optical system either located in space or corrected by an adaptive o to Strehl ratios of about 70% and higher.
Anand Sivaramakrishnan, Ben R. Oppenheimer, James R. Graham, Labeyrie A., Macintosh B., Marshall D. Perrin, Russell B. Makidon, Watson S. M.   +7 more
core   +1 more source

Brownian excursion area, Wright's constants in graph enumeration, and other Brownian areas [PDF]

, 2007
This survey is a collection of various results and formulas by different authors on the areas (integrals) of five related processes, viz.\spacefactor =1000 Brownian motion, bridge, excursion, meander and double meander; for the Brownian motion and bridge,
Janson, Svante
core   +6 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Intersection numbers of Riemann surfaces from Gaussian matrix models

, 2007
We consider a Gaussian random matrix theory in the presence of an external matrix source. This matrix model, after duality (a simple version of the closed/open string duality), yields a generalized Kontsevich model through an appropriate tuning of the ...
A. Hashimoto, A. Okounkov, C.Faber, D. Gaiotto, E. Brézin, E. Brézin, E. Brézin, E. Brézin, E. Brézin, E. Brézin, E. Brézin, E. Brézin, E. Witten, E. Witten, Edouard Brézin, K. Efetov, K. Liu, M.R. Zirnbauer, R.C. Penner, Shinobu Hikami, T.J. Jarvis   +20 more
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source