Results 41 to 50 of about 195,521 (254)

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

How the AIS can Improve its Contributions to the UN’s Sustainability Development Goals: Towards A Framework for Scaling Collaborations and Evaluating Impact [PDF]

, 2021
In June, 2019, the Association for Information Systems (AIS) adopted a new approach to addressing global sustainability issues by establishing the AIS Sustainability Task Force (AIS STF).
Elliot, Steve, Watson, Richard T., Iyer, Lakshmi, Feizabadi, Ali, Webster, Jane, Sharda, Ramesh, Gupta, Ashish, Shin, Namchul, Corbett, Jacqueline, Farkas, Dan, Sen, Sagnika, Thapa, Devinder   +11 more
core   +1 more source

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Visualization, Vulnerability and Manipulation in Internal Communications Systems on the Navigation Bridges [PDF]

TransNav
This paper is the continuation of a project previously presented for the training of students in both the Bachelor's and Master's degrees in Radio Engineering.
Raquel Esther Rey-Charlo, Francisco Jose Visglerio Varo   +1 more
doaj   +1 more source

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Two-Stage Maritime Anomaly Detection: Unsupervised Outlier Filtering and Optimized Bidirectional LSTM on Southeast Asian AIS Data

Journal of Applied Informatics and Computing
This paper presents a two-stage framework for detecting anomalous vessel trajectories in Automatic Identification System (AIS) data from Southeast Asian waters, addressing challenges of high traffic density, diverse vessel behaviors, and severe class ...
Daffa Afaf Firmansyah, Erna Zuni Astuti
doaj   +1 more source

African spirituality in the Johane Masowe Chishanu religious movement in Zimbabwe: A Christian church-sect dichotomy

HTS Teologiese Studies/Theological Studies, 2021
This study explored the impact of African indigenous spirituality on African indigenous churches (AICs), particularly in the Zimbabwean context, a special focus was on the Johane Masowe Chishanu (JMC) religious movement spirituality.
Phillip Musoni
doaj   +1 more source

AIS SCLC 2021 Final Awards and Closing Session [PDF]

, 2021
This is a recording of the AIS National SCLC 2021 Final Awards and Closing ...
Lopes, Alex
core  

Chlorine‐Functionalized Silane‐Modified Copper Electrocatalyst for Enhanced CO2 Reduction to Multi‐Carbon Products

Advanced Science, EarlyView.
A chlorine‐functionalized silane modifier (CPTMS) is introduced to cooperatively regulate CO2 reduction to C2+ products on Cu‐based catalysts. Dual‐functional interface sequentially enhances CO2 activation, intermediates protonation and C─C coupling, delivering a 5‐fold increase in C2+ faradaic efficiency (FE, 75% vs.
Ying Ying Ch'ng, Sankhadip Saha, Ming Zhang, Shujie Zhou, Lixue Jiang, Putri Ramadhany, Jitraporn Vongsvivut, Adrian Cernescu, Priyank Vijaya Kumar, Yihao Shan, Zhipeng Ma, Xiaoxuan Luo, Rahman Daiyan, Zhaojun Han, Rose Amal   +14 more
wiley   +1 more source

Successful Treatment Outcome in a Patient with Bilateral Cataract and Associated Occipital Infarction Following an Acute Ischemic Stroke Post COVID-19 Vaccination – A Rare Case Report

TNOA Journal of Ophthalmic Science and Research
Visual loss in haemorrhagic occipital infarction following acute ischemic stroke (AIS) can be sudden and devastating. We present the successful management of a 50-year-old man, who had suffered an AIS 2 years ago following the first dose of the ChAdOx1 ...
Lily Daniel, Maria Pramod, Kalpana Ramamoorthy, Aditi Gopinath   +3 more
doaj   +1 more source