Results 61 to 70 of about 201,258 (298)

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

AI, AI, AI

Oil Information Technology Journal
Oil IT Journal concatenates some recent announcements around artificial intelligence. On the pro side we have a Baringa report on an AI-powered revolution in energy. TotalEnergies’ 20,000 AI models and MLOps. The OMG’s Agentic AI periodic table. On the maybe not side, half of AI projects for the chop (Gartner), AI agents fail 70% of the time (CMU ...
  +5 more sources

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Barnearbeidsmigrasjoner i ulike landskap: En sammenstilling av barns arbeidsvandringer i Vest-Agder (1830–1910) og Vest-Afrika (1980–2009)

Barn, 2009
De historiske norske barnevandringene på Sørlandet og dagens barnearbeidsmigrasjoner i Vest-Afrika har flere fellestrekk. Ved å sammenstille dokumentasjon av ulike deler av de to fenomenene søker denne artikkelen å nedtone forestillingen om at ...
Anne Kielland
doaj   +1 more source

From ”Explainable AI” to ”Graspable AI”

Proceedings of the Fifteenth International Conference on Tangible, Embedded, and Embodied Interaction, 2021
Since the advent of Artificial Intelligence (AI) and Machine Learning (ML), researchers have asked how intelligent computing systems could interact with and relate to their users and their surroundings, leading to debates around issues of biased AI systems, ML black-box, user trust, user’s perception of control over the system, and system’s ...
Maliheh Ghajargar, Jeffrey Bardzell, Alison Smith-Renner, Peter Gall Krogh, Kristina Höök, David Cuartielles, Laurens Boer, Mikael Wiberg   +7 more
openaire   +6 more sources

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Two-Stage Maritime Anomaly Detection: Unsupervised Outlier Filtering and Optimized Bidirectional LSTM on Southeast Asian AIS Data

Journal of Applied Informatics and Computing
This paper presents a two-stage framework for detecting anomalous vessel trajectories in Automatic Identification System (AIS) data from Southeast Asian waters, addressing challenges of high traffic density, diverse vessel behaviors, and severe class ...
Daffa Afaf Firmansyah, Erna Zuni Astuti
doaj   +1 more source

African spirituality in the Johane Masowe Chishanu religious movement in Zimbabwe: A Christian church-sect dichotomy

HTS Teologiese Studies/Theological Studies, 2021
This study explored the impact of African indigenous spirituality on African indigenous churches (AICs), particularly in the Zimbabwean context, a special focus was on the Johane Masowe Chishanu (JMC) religious movement spirituality.
Phillip Musoni
doaj   +1 more source

Responsible AI in Marketing: AI Booing and AI Washing Cycle of AI Mistrust [PDF]

International Journal of Market Research
The growing integration of Artificial Intelligence (AI) in marketing has introduced both opportunities and challenges, particularly concerning consumer trust. This paper critically examines two emerging phenomena: AI Washing , where companies exaggerate AI capabilities for marketing advantage,
Selcen Ozturkcan, Ayşe Aslı Bozdağ
openaire   +2 more sources

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

Advanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi, Qun Liu, Baohua Zou, Wenyuan Wang, Xinlong Qiao, Lin Gao, Chaoxu Miao, Ningning Huang, Shuqing Tang, Rui Guo, Changqing Zeng, Ce Jia, Yuanchao Xue, Xuejun Guo, Jianjun Chen, Huiwen Wang, Guangju Ji   +16 more
wiley   +1 more source