Results 151 to 160 of about 80,331 (267)
AKI - Experimental [PDF]
Nephrology Dialysis Transplantation, 2012 K. Kaynar, K. Kaynar, S. Ersoz, R. Aliyazioglu, A. Uzun, S. Ulusoy, S. Al, G. Ozkan, M. Cansiz, J.-P. Bertocchio, J. Lancon, S. El Moghrabi, G. Galmiche, J.-P. Duong Van Huyen, P. Rieu, F. Jaisser, G. Albertoni, S. Andrade, J. A. Barreto, F. Borges, N. Schor, W.-Y. Ho, S.-H. Chen, C.-J. Tseng, A. Bienholz, T. Feldkamp, J. M. Weinberg, J. Suller Garcia, M. Naves, F. Borges, N. Schor, F. Borges, L. Aparecida Reis, M. d. J. Simoes, N. Schor, W. S Almeida, V. Moreau Longo, H. R. C. Segreto, N. Schor, A. Ghoneim, A. Elkholy, T. Medhat Abbas, M. El Hadeedy, F. Elhusseini, B. Elessawey, E. Eltanaihy, A. Lotfy, S. Eldesoky, H. Sheashaa, M. Sobh, D. M. Minning, D. Warnock, A. S. Mohamed, J. B. Wirthlin, S. R. Chintalacharuvu, L. Boone, R. M. Brenner, F. Borges, L. Aparecida Reis, M. d. J. Simoes, N. Schor, J. Santina Christo, C. Dos Santos Passos, L. Aparecida Reis, D. Rene de Alencar, J. Suller Garcia, N. Schor, A. C. De Braganca, D. Canale, J. G. Goncalves, T. P. B. Brandao, M. H. M. Shimizu, R. A. Volpini, A. C. Seguro, L. Andrade, D. Canale, A. C. De Braganca, J. G. Goncalves, T. P. B. Brandao, M. H. M. Shimizu, R. A. Volpini, L. Andrade, A. C. Seguro, J.-W. Lee, H. K. Kim, W. Y. Cho, S.-K. Jo, E. Cho, K. Hocherl, C. Schmidt, S. R. Mulay, O. P. Kulkarni, K. V. Rupanagudi, A. Migliorini, H. Liapis, H.-J. Anders, I. Pevzner, A. Chupyrkina, E. Plotnikov, D. Zorov, J.-M. Lopez-Novoa, N. Eleno, F. Perez-Barriocanal, M. Arevalo, N. Docherty, G. Castellano, C. Divella, A. Loverre, A. Stasi, C. Curci, M. Rossini, P. Ditonno, M. Battaglia, M. R. Daha, C. Van Kooten, L. Gesualdo, F. P. Schena, G. Grandaliano, H. Tsuda, N. Kawada, H. Iwatani, T. Moriyama, S. Takahara, H. Rakugi, Y. Isaka, G. Schley, J. Kalucka, B. Klanke, J. Jantsch, S. Olbrich, J. Baumgartl, K. Amann, K.-U. Eckardt, A. Weidemann, A. Dolgolikova, V. Pilotovich, G. Ivanchik, I. Shved, N. F. Banki, Z. Antal, A. Hosszu, S. Koszegi, A. Vannay, L. Wagner, A. Prokai, V. Muller, A. J. Szabo, A. Fekete, S. Farrag, S. Abulasrar, , M. Salama, M. Amin, A. Ali, H. Sheashaa, M. Sobh, I. Rubera, C. Duranton, M. Cougnon, N. Melis, M. Tauc, E. Plotnikov, D. Zorov, A. Chupyrkina, S. Jankauskas, M. Morosanova, I. Pevzner, N. Pulkina, L. Zorova, Y. T. Shin, S. S. Kim, Y. K. Chang, D. E. Choi, K.-R. Na, K. W. Lee, J.-Y. Choi, D.-C. Jin, J.-H. Cha, R. Schneider, B. Betz, M. Meusel, C. Held, C. Wanner, M. Gekle, C. Sauvant, A. Pisani, R. Rossano, A. Mancini, N. Arfian, K. Yagi, K. Nakayama, H. Ali, D. S. Mayasari, E. Purnomo, N. Emoto, S. Efrati, S. Berman, R. Abu Hamad, J. Weissgarten, C. R. Scherbaum, R. Allam +199 moreopenaire +1 more sourceNeutrophil‐Macrophage Interactions Shape Inflammatory Macrophage Remodeling in Gastric Cancer During Chemo‐Immunotherapy
Cancer Science, EarlyView.PD‐1 blockade combined with chemotherapy induces MHC‐II+ inflammatory neutrophils in gastric cancer, which engage in dynamic crosstalk with macrophages to remodel the tumor microenvironment toward a pro‐inflammatory state, thereby amplifying antitumor immune responses.Keita H. Nagaoka, Hiroki Yamashita, Chiaki Mashima, Guoqiang Zhang, Hitoshi Saito, Tatsunori Minamide, Takuya Nakatsuru, Ryo Kamata, Shunsuke A. Sakai, Gaku Yamamoto, Tomoko Y. Morita, Kazuki Nakai, Yumi Hakozaki, Kumi Kinoshita, Yui Takahashi, Izuma Nakayama, Akihito Kawazoe, Sai M. Pulukuri, Yuko Ishii, Hiroshi Haeno, Yukie Kashima, Kohei Shitara, Tomonori Yano, Takeshi Saito, Akihiro Ohashi +24 morewiley +1 more sourceTREM2 in Macrophages Promotes Renal Fibrosis via Activation of β‐Catenin Signalling Pathway in Obstructive Nephropathy
Cell Proliferation, EarlyView.Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) promotes obstructive nephropathy progression by activating the β‐catenin signalling pathway, driving M2 macrophage polarisation, migration and fibrogenic gene expression. targeted inhibition of TREM2 thus represents a promising novel strategy against renal fibrosis.Jia Wei, Zixia Li, Gengyu Du, Ting Chen, Min Yang, Zhen Yuan, Yidan Zheng, Xiang Yan +7 morewiley +1 more sourceTargeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases
Cell Proliferation, EarlyView.m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang +7 morewiley +1 more sourceLATAM-AKID registry: an international multicentre, observational study of acute kidney injury requiring dialysis in Latin America. [PDF]
BMJ OpenRehman AU, Nombera-Aznaran N, Renzi S, Ghazi L, Tolwani AJ, Molano Trivino A, Reis T, Vega-Vega O, Rizo-Topete L, Claure-Del Granado R, Neyra JA. +10 moreeuropepmc +1 more sourceGlycaemic penalty index as an independent predictor of healthcare‐associated infection in surgical inpatients: A nested cohort study from the STOIC‐D surgery trial
Diabetic Medicine, EarlyView.Higher glycaemic burden, measured by the Glycaemic Penalty Index (GPI), was independently associated with increased risk of healthcare‐associated infection in surgical inpatients. GPI provides a single, clinically interpretable summary of both hyperglycaemia and hypoglycaemia. Abstract Aims
To evaluate the utility of the Glycemic Penalty Index (GPI), a Gabrielle Blomson, Rahul D. Barmanray, Mervyn Kyi, Peter G. Colman, Leon J. Worth, Minh V. Le, Emily Sun, Spiros Fourlanos +7 morewiley +1 more source