Results 151 to 160 of about 80,331 (267)

AKI - Experimental [PDF]

open access: yesNephrology Dialysis Transplantation, 2012
K. Kaynar   +199 more
openaire   +1 more source

Neutrophil‐Macrophage Interactions Shape Inflammatory Macrophage Remodeling in Gastric Cancer During Chemo‐Immunotherapy

open access: yesCancer Science, EarlyView.
PD‐1 blockade combined with chemotherapy induces MHC‐II+ inflammatory neutrophils in gastric cancer, which engage in dynamic crosstalk with macrophages to remodel the tumor microenvironment toward a pro‐inflammatory state, thereby amplifying antitumor immune responses.
Keita H. Nagaoka   +24 more
wiley   +1 more source

A Semi‐Analytical Energy Model for Particle‐Based Fluid Simulation Involving Complex Moving Boundaries

open access: yesComputer Graphics Forum, EarlyView.
Abstract While semi‐analytical boundary handling techniques have proven effective for modeling particle‐based fluid‐solid interactions, they can become unstable when applied to mesh boundaries undergoing dynamic motion or featuring complex, sharp geometries.
Junyuan Liu   +5 more
wiley   +1 more source

TREM2 in Macrophages Promotes Renal Fibrosis via Activation of β‐Catenin Signalling Pathway in Obstructive Nephropathy

open access: yesCell Proliferation, EarlyView.
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) promotes obstructive nephropathy progression by activating the β‐catenin signalling pathway, driving M2 macrophage polarisation, migration and fibrogenic gene expression. targeted inhibition of TREM2 thus represents a promising novel strategy against renal fibrosis.
Jia Wei   +7 more
wiley   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

open access: yesCell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du   +7 more
wiley   +1 more source

LATAM-AKID registry: an international multicentre, observational study of acute kidney injury requiring dialysis in Latin America. [PDF]

open access: yesBMJ Open
Rehman AU   +10 more
europepmc   +1 more source

Glycaemic penalty index as an independent predictor of healthcare‐associated infection in surgical inpatients: A nested cohort study from the STOIC‐D surgery trial

open access: yesDiabetic Medicine, EarlyView.
Higher glycaemic burden, measured by the Glycaemic Penalty Index (GPI), was independently associated with increased risk of healthcare‐associated infection in surgical inpatients. GPI provides a single, clinically interpretable summary of both hyperglycaemia and hypoglycaemia. Abstract Aims To evaluate the utility of the Glycemic Penalty Index (GPI), a
Gabrielle Blomson   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy