Results 11 to 20 of about 269 (84)

The Attribution of the Criteria for Critical Appraisal of Content in the Hanafīs’ Hadīth Understanding to Abū Hanīfa [PDF]

, 2021
Abū Hanīfa Numan b. Sabit is a leading Islamic scholar who lived between the late first and the mid-second century Hijri, (the eighth and ninth centuries A.D.).
Mutlu Gül
core   +2 more sources

Molecular modelling assisted design of napthalimide-dihydropyrimidinone conjugates as potential cytotoxic agents

Journal of Saudi Chemical Society, 2021
A molecular modelling assisted design of napthalimide-dihydropyrimidinone conjugates as potential cytotoxic agents based on a lead molecule (elinafide) is described.
M. Shaheer Malik, Syed Farooq Adil, Zaki S. Seddigi, Moataz Morad, Rabab S. Jassas, Ismail I. Thagafi, Hatem M. Altass, Qazi Mohammad Sajid Jamal, Syed Riyaz, Reem I. Alsantali, Abdulrahman A. Al-Warthan, Mohammad Azam Ansari, Saleh A. Ahmed   +12 more
doaj   +1 more source

Multicomponent synthesis, cytotoxicity, and computational studies of novel imidazopyridazine-based N-phenylbenzamides

Journal of Saudi Chemical Society, 2022
A one-pot multicomponent synthesis and application of new imidazopyridazine based N-phenylbenzamides is described. An atom-economical method involving dimethyl phthalate, substituted anilines, and pyridazine-4,5-diamine provided the desired compounds in ...
M. Shaheer Malik, Reem A. Alsantali, Abdullah Y.A. Alzahrani, Qazi Mohammad Sajid Jamal, Essam M. Hussein, Khalid A. Alfaidi, Munirah M. Al-Rooqi, Rami J. Obaid, Meshari A. Alsharif, Syed Farooq Adil, Rabab S. Jassas, Ziad Moussa, Saleh A. Ahmed   +12 more
doaj   +1 more source

Precision management of post‐COVID pain: An evidence and clinical‐based approach

European Journal of Pain, Volume 27, Issue 9, Page 1107-1125, October 2023., 2023
Abstract Background Pain after a SARS‐CoV‐2 acute infection (post‐COVID pain) is becoming a new healthcare emergency but remains underestimated and most likely undertreated due to a lack of recognition of the phenomenon and knowledge of the underlying pain mechanisms.
César Fernández‐de‐las‐Peñas, Jo Nijs, Rocco Giordano, Lars Arendt‐Nielsen   +3 more
wiley   +1 more source

Makanan Haram dan Pengaruhnya dalam Kehidupan [PDF]

, 2020
This paper explains the interpretation of Surah al-Mā’idah verses 3-5 regarding unlawful food and its effect on life. Humans being are living creatures who need to food and drink, so Allah commands them to fulfill their daily lives in a good way. Teh Qur’
Anshori, Muhammad
core   +2 more sources

Reinventing Konsep Muhkam-Mutasyābih dan Pengembangannya dalam Tafsir al-Qur’an Kontekstual [PDF]

, 2021
Discourse of Muhkām-Mutasyābih which has been discussed in the classical literatures of ulūm al-Qur‘ān was getting worse because of some shift meanings especially specialization that limits muhkām-mutasyābih discussion on the teological verses of the ...
Amin, Ahmad Syaifuddin
core   +2 more sources

Combining radiation and the ATR inhibitor berzosertib activates STING signaling and enhances immunotherapy via inhibiting SHP1 function in colorectal cancer

Cancer Communications, Volume 43, Issue 4, Page 435-454, April 2023., 2023
Abstract Background Immune checkpoint inhibitors (ICIs) targeting programmed cell death protein 1 (PD‐1) and programmed death‐ligand 1 (PD‐L1) have shown a moderate response in colorectal cancer (CRC) with deficient mismatch repair (dMMR) functions and poor response in patients with proficient MMR (pMMR). pMMR tumors are generally immunogenically “cold”
Chaofan Liu, Xi Wang, Wan Qin, Jingyao Tu, Chunya Li, Weiheng Zhao, Li Ma, Bo Liu, Hong Qiu, Xianglin Yuan   +9 more
wiley   +1 more source

New Imidazole-Based N-Phenylbenzamide Derivatives as Potential Anticancer Agents: Key Computational Insights

Frontiers in Chemistry, 2022
An efficient atom-economical synthetic protocol to access new imidazole-based N-phenylbenzamide derivatives is described. A one-pot three-component reaction was utilized to provide a series of N-phenylbenzamide derivatives in a short reaction time (2–4 h)
M. Shaheer Malik, Reem I. Alsantali, Qazi Mohammad Sajid Jamal, Zaki S. Seddigi, Moataz Morad, Meshari A. Alsharif, Essam M. Hussein, Essam M. Hussein, Rabab S. Jassas, Munirah M. Al-Rooqi, Zainularifeen Abduljaleel, Ahmed O. Babalgith, Hatem M. Altass, Ziad Moussa, Saleh A. Ahmed, Saleh A. Ahmed   +15 more
doaj   +1 more source

Climate‐driven substitution of foundation species causes breakdown of a facilitation cascade with potential implications for higher trophic levels

Journal of Ecology, Volume 110, Issue 9, Page 2132-2144, September 2022., 2022
The cold‐water kelp Laminaria hyperborea supports diverse and abundant stipe assemblages, which represent an important link to higher trophic levels. Climate‐driven substitution of a warm‐adapted kelp Laminaria ochroleuca resulted in the breakdown of a facilitative habitat cascade, leading to lower biodiversity and faunal abundance, with potential ...
Dan A. Smale, Harry Teagle, Stephen J. Hawkins, Helen L. Jenkins, Nadia Frontier, Cat Wilding, Nathan King, Mathilde Jackson‐Bué, Pippa J. Moore   +8 more
wiley   +1 more source

SUMOylation of Kir7.1 participates in neuropathic pain through regulating its membrane expression in spinal cord neurons

CNS Neuroscience &Therapeutics, Volume 28, Issue 8, Page 1259-1267, August 2022., 2022
SNI markedly decreased the expression of Kir7.1 and upregulated SUMOylated‐Kir7.1 in the spinal dorsal horn accompanied by mechanical hypersensitivity. Blocking Kir7.1 with the specific antagonist or knockdown kir7.1 by siRNA led to mechanical allodynia. Moreover, inhibited SUMOylation can increase the spinal surface Kir7.1 expression.
You‐You Lv, Han Wang, Hai‐Ting Fan, Ting Xu, Wen‐Jun Xin, Rui‐Xian Guo   +5 more
wiley   +1 more source