Results 121 to 130 of about 614,051 (372)

Temperature dependence of optical rotation study on parity-violating phase transition of D-, L-, and DL-alanine [PDF]

arXiv, 2002
Chiral molecules are characterized by a specific optical rotation angle. An experimental method was presented to dissect the temperature dependence of the optical rotation angle with the molecular chirality of D-alanine, L-alanine and DL-alanine crystals. Salam hypothesis predicted that quantum mechanical cooperative and condensation phenomena may give
arxiv  

Biomimetic Co‐delivery of Lenvatinib and FePt Nanoparticles for Enhanced Ferroptosis/Apoptosis Treatment of Hepatocellular Carcinoma

Advanced Healthcare Materials, EarlyView.
This study introduces a novel HCC treatment using poly lactic‐co‐glycolic acid (PLGA) nanoparticles encased in HCC cell membranes to co‐deliver Lenvatinib and FePt nanoparticles. This approach improves treatment efficacy by enhancing ferroptosis and apoptosis.
Feichao Xuan, Xingyang Zhao, Weiran Pang, Zirong Li, Xiangyi Yin, Weizhong Xie, Xiaojun Zeng, Liming Nie, Junying Yang, Shiying Li, Puxiang Lai, Chihua Fang   +11 more
wiley   +1 more source

Genetically Predicted Circulating Concentrations of Alanine and Alanine Aminotransferase Were Associated with Prostate Cancer Risk

Clinical Epidemiology, 2022
Shaoxue Yang1 *, Jie Song2 *, Hong Yang,2 Wei Liu,2 Yuqing Jiang,2 Xiaohui Sun,2 Ding Ye,2 Songxiao Xu,1 Yingying Mao2 1The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine ...
Yang S, Song J, Yang H, Liu W, Jiang Y, Sun X, Ye D, Xu S, Mao Y   +8 more
doaj  

SAFETY study: alanine aminotransferase cutoff values are set too high for reliable detection of pediatric chronic liver disease.

Gastroenterology, 2010
BACKGROUND & AIMS The appropriate alanine aminotransferase (ALT) threshold value to use for diagnosis of chronic liver disease in children is unknown. We sought to develop gender-specific, biology-based, pediatric ALT thresholds.
J. Schwimmer, Winston Dunn, G. Norman, Perrie E. Pardee, M. Middleton, N. Kerkar, C. Sirlin   +6 more
semanticscholar   +1 more source

A Comparison of the Mechanical Properties of ECM Components and Synthetic Self‐Assembling Peptides

Advanced Healthcare Materials, EarlyView.
Self‐assembling peptide hydrogels are increasingly utilized in biomedical applications. The authors review the key mechanical properties of these structures across multiple size scales and compare them to that of native extracellular matrix components, which are found to display a much wider range of structural attributes.
Alex Hartley, Philip Michael Williams, Alvaro Mata   +2 more
wiley   +1 more source

Photoelectron Circular Dichroism of Aqueous-Phase Alanine [PDF]

arXiv
Amino acids and other small chiral molecules play key roles in biochemistry. However, in order to understand how these molecules behave in vivo, it is necessary to study them under aqueous-phase conditions. Photoelectron circular dichroism (PECD) has emerged as an extremely sensitive probe of chiral molecules, but its suitability for application to ...
arxiv  

Arrow of time and non-Markovianity in the non equilibrium folding/unfolding of alanine decapeptide in vacuo [PDF]

arXiv, 2009
We present non equilibrium molecular dynamics experiments of the unfolding and refolding of an alanine decapeptide in vacuo subject to a Nose-Hoover thermostat. Forward (unfolding) and reverse (refolding) work distribution are numerically calculated for various duration times of the non equilibrium experiments. Crooks theorem is accurately verified for
arxiv  

Revised mechanism of d-alanine incorporation into cell wall polymers in Gram-positive bacteria

Microbiology, 2013
Teichoic acids (TAs) are important for growth, biofilm formation, adhesion and virulence of Gram-positive bacterial pathogens. The chemical structures of the TAs vary between bacteria, though they typically consist of zwitterionic polymers that are ...
N. Reichmann, C. P. Cassona, A. Gründling   +2 more
semanticscholar   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

CORRELATION OF RESPIRATORY ACTIVITY WITH PHASES OF SPORE GERMINATION AND GROWTH IN BACILLUS MEGATERIUM AS INFLUENCED BY MANGANESE AND l -ALANINE [PDF]

, 1956
Hillel S. Levinson, Mildred T. Hyatt
openalex   +1 more source