Results 281 to 290 of about 803,336 (334)

A novel scoring system to identify patients at low risk for hepatocellular carcinoma five years after DAA-Induced sustained virological response: a retrospective cohort study. [PDF]

BMC Gastroenterol
Fujii H, Nishimura T, Kimura H, Mitsumoto Y, Shima T, Seko Y, Moriguchi M, Kataoka S, Tanaka S, Ishikawa H, Takami S, Nagao Y, Umemura A, Itoh Y, Yamaguchi K.   +14 more
europepmc   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

AlphaFold3 prediction of protein-protein complex: Is it ready for thermodynamic analysis? [PDF]

Comput Struct Biotechnol J
Liu X, Pang K, Wu H, Chong B, Yin Z, Sun Z, Wang X.   +6 more
europepmc   +1 more source

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

Advanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera, Lena Kühn, Lisa Jungbluth, Verian Bader, Laura J. Krause, David Kartte, Elias Adriaenssens, Sascha Martens, Jörg Tatzelt, Carsten Sachse, Konstanze F. Winklhofer   +10 more
wiley   +1 more source

Impact of D-Amino Acids in Schizophrenia. [PDF]

Biomolecules
Dursun SM, Dursun LH, Baker GB.
europepmc   +1 more source

A Dynamic DNA Nano‐Antioxidant Targeting Galectin‐3 Attenuates Liver Fibrosis via Reducing Macrophage Oxidative Stress

Advanced Science, EarlyView.
This study developed a dynamic DNA nano‐antioxidant (DDN) for Galectin‐3 siRNA delivery, specifically targeting hepatic macrophages to suppress ROS‐driven fibrosis. DDN enhanced hepatic accumulation, restored NRF2 signaling, and attenuated oxidative stress, collagen deposition, and fibrotic progression in a CCl4‐induced cirrhosis model, demonstrating ...
Mengjia Peng, Jianguo Xu, Youjian Hong, Fei Fang, Yan Li, Duo Ci, Bowen Wang   +6 more
wiley   +1 more source

Seq2Bind webserver for binding site prediction from sequences using fine-tuned protein language models. [PDF]

NAR Genom Bioinform
Ma X, Dey S, Sr V, Zelinski C, Li Q, Chowdhury R.   +5 more
europepmc   +1 more source

Reviewer #1 (Public review): Salmonella exploits host- and bacterial-derived β-alanine for replication inside host macrophages

openalex   +1 more source

From wheat bran to equine gut: the <i>in vitro</i> fermentation dynamics of aleurone. [PDF]

Front Physiol
Boshuizen B, Willems M, De Maré L, Hosotani G, De Oliveira JE, Horemans B, Vidal Moreno De Vega C, Verdegaal EJMM, Delesalle C.   +8 more
europepmc   +1 more source

Exploring the interaction hotspots of p-glycoprotein with herbal bioactives: In silico insights for integrative Ayurvedic therapeutics. [PDF]

J Ayurveda Integr Med
Roy C, Ghosh P.
europepmc   +1 more source