Results 281 to 290 of about 897,077 (404)

The E3 Ubiquitin Ligase ARIH1 Facilitates Colorectal Cancer Progression by Promoting Oxidative Phosphorylation via the Mitochondrial Translocation of K63‐Linked Ubiquitinated PHB1

Advanced Science, EarlyView.
The RBR E3 ubiquitin ligase ARIH1, which is upregulated in colorectal cancer cells, promotes cell growth and metastasis and correlates with an unfavorable CRC prognosis. Mechanistically, ARIH1 catalyzes K63‐linked ubiquitination of PHB1, enhancing the interaction between PHB1 and Akt.
Ying Tong, Zhenling Wang, Yong Wang, Yang Chen, Hongqiang Zhang, Yunfei Lu, Lei Xu, Hengyang Shen, Changzhi Huang, Min Zhao, Wenjie Li, Shuai Wang, Yu Shao, Zan Fu   +13 more
wiley   +1 more source

The relationship between amino acid intake patterns and both general and central obesity. [PDF]

BMC Nutr
Alijani F, Ahmadi A, Mohammadpour N, Jazayeri S, Abolghasemi J, Shahinfar H, Khorasanian AS, Rimaz S.   +7 more
europepmc   +1 more source

THE DEVELOPMENTAL SIGNIFICANCE OF ALANINE DEHYDROGENASE IN BACILLUS SUBTILIS

, 1964
Ernst Freese, Sang Won Park, Michael Cashel   +2 more
openalex   +1 more source

Radiolysis of Solid L-α-Alanine [PDF]

, 1967
Atsuko Minegishi, Youichi Shinozaki, Gisuke Meshitsuka   +2 more
openalex   +1 more source

Vitamin E and changes in serum alanine aminotransferase levels in patients with non‐alcoholic steatohepatitis

Alimentary Pharmacology and Therapeutics, 2013
J. Hoofnagle, M. L. Natta, D. Kleiner, J. Clark, K. Kowdley, R. Loomba, B. Neuschwander‐Tetri, A. Sanyal, J. Tonascia   +8 more
semanticscholar   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Poor Abilities of Noninvasive Biomarkers to Assess Esophagogastric Varices and Portal Hypertensive Gastropathy. [PDF]

Biomark Insights
Abassa KK, Guo X, Tan S, Liang Z, Tan S.
europepmc   +1 more source

EFFECT OF THYROXINE ON L-ALANINE INCORPORATION INTO PROTEINS OF THE SECRETORY GRANULES OF RAT ANTERIOR PITUITARY

, 1968
Teiichiro Tonoue, Kiyoshi Yamamoto
openalex   +2 more sources

Neoadjuvant Chemotherapy With Cisplatin Up‐Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14‐Mediated EMT Activation

Advanced Science, EarlyView.
Oral squamous cell carcinoma cells exhibit upregulated expression of GSDMD upon exposure to low‐dose cisplatin chemotherapy, which subsequently interacts with MMP14 through its N‐terminal domain, activating the epithelial‒mesenchymal transition (EMT) process and promoting the lymph node metastasis of oral squamous cell carcinoma.
Zixian Huang, Qiming Jiang, Qianyu Zhang, Nan Lu, Xi Rui, Rui Chen, Yan Wang, Yuepeng Wang, Xiaoding Xu, Zhiquan Huang   +9 more
wiley   +1 more source

Permeability selection of biologically relevant membranes matches the stereochemistry of life on Earth. [PDF]

PLoS Biol
Goode O, Łapińska U, Morimoto J, Glover G, Milner DS, Santoro AE, Pagliara S, Richards TA.   +7 more
europepmc   +1 more source