Results 301 to 310 of about 803,336 (334)
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Current Sports Medicine Reports, 2012
β-Alanine is rapidly developing as one of the most popular sport supplements used by strength/power athletes worldwide. The popularity of β-alanine stems from its unique ability to enhance intramuscular buffering capacity and thereby attenuating fatigue.
Hoffman, Jay R. +2 more
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β-Alanine is rapidly developing as one of the most popular sport supplements used by strength/power athletes worldwide. The popularity of β-alanine stems from its unique ability to enhance intramuscular buffering capacity and thereby attenuating fatigue.
Hoffman, Jay R. +2 more
openaire +3 more sources
Combinatorial alanine-scanning
Current Opinion in Chemical Biology, 2001Combinatorial libraries of alanine-substituted proteins can be used to rapidly identify residues important for protein function, stability and shape. Each alanine substitution examines the contribution of an individual amino acid sidechain to the functionality of the protein.
K L, Morrison, G A, Weiss
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The Journal of Physical Chemistry A, 2014
Two complexes of alanine with water, alanine-(H2O)n (n = 1,2), have been generated by laser ablation of the amino acid in a supersonic jet containing water vapor and characterized using Fourier transform microwave spectroscopy. In the observed complexes, water molecules bind to the carboxylic group of alanine acting as both proton donors and acceptors.
Vaquero, Vanesa +6 more
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Two complexes of alanine with water, alanine-(H2O)n (n = 1,2), have been generated by laser ablation of the amino acid in a supersonic jet containing water vapor and characterized using Fourier transform microwave spectroscopy. In the observed complexes, water molecules bind to the carboxylic group of alanine acting as both proton donors and acceptors.
Vaquero, Vanesa +6 more
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Amperometric Alanine Electrode
Analytical Letters, 1993Abstract An amperometric enzyme electrode for L-Alanine determination was developed. The probe is based on a platinum electrode which senses the hydrogen peroxide produced by the enzymatic reactions catalyzed by two enzymes: alanine aminotransferase (ALT) and glutamate oxidase.
PALLESCHI, GIUSEPPE +5 more
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Acta Crystallographica Section C Crystal Structure Communications, 2001
A determination of the structure of the title compound, C3H7NO2, leads to an accurate description of its molecular dimensions and crystal packing. As in the structure of the L-isomer, the molecules aggregate into alternating layers, each consisting of only one type of isomer. The molecules in each layer are interconnected through head-to-tail sequences
M, Subha Nandhini +2 more
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A determination of the structure of the title compound, C3H7NO2, leads to an accurate description of its molecular dimensions and crystal packing. As in the structure of the L-isomer, the molecules aggregate into alternating layers, each consisting of only one type of isomer. The molecules in each layer are interconnected through head-to-tail sequences
M, Subha Nandhini +2 more
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Expert Opinion on Investigational Drugs, 2011
Angiogenesis inhibition represents a rational therapeutic strategy in the management of solid tumors. Brivanib is a dual tyrosine kinase inhibitor with selectivity against VEFGR-2 and FGFR.This review provides an updated summary of preclinical and clinical experience with brivanib in cancer.
Ivan, Diaz-Padilla, Lillian L, Siu
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Angiogenesis inhibition represents a rational therapeutic strategy in the management of solid tumors. Brivanib is a dual tyrosine kinase inhibitor with selectivity against VEFGR-2 and FGFR.This review provides an updated summary of preclinical and clinical experience with brivanib in cancer.
Ivan, Diaz-Padilla, Lillian L, Siu
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Inactivation of alanine aminotransferase by the neurotoxin β-cyano-L-alanine
Biochemical and Biophysical Research Communications, 1980Abstract β-Cyano-L-alanine inactivates pig heart alanine aminotransferase. The nitrile and enzyme form a freely dissociable Michaelis complex which rearranges to a form of inactive enzyme. The inactivated enzyme slowly recovers activity at 25° in 100 mM phosphate buffer, pH 7.4. The observations are consistent with a mechanism of inactivation similar
T A, Alston +3 more
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Serum alanine assay with an enzymic micromethod (L-alanine dehydrogenase)
Clinica Chimica Acta, 1978L-Alanine was measured by an enzymic micromethod in serum after treatment with perchloric acid, as well as after ultrafiltration through collodium membrane filters. Serum L-alanine was also determined by an automated column chromatographic technique. Using the enzymic method, spuriously increased L-alanine levels could be obtained due to the absorbent ...
A, Berg, W, Gerok, J, Keul
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Inorganica Chimica Acta, 1968
Abstract The reactions of alkali hexanitrocobaltates(III) with DL-alanine, D-alanine, L-alanine, and β-alanine have been investigated. Thereby new classes of alkali dinitro-bis (aminoacido)cobaltates(III), M[CoAm 2 (NO 2 ) 2 ] were obtained. It was established that the products obtained contain two nitro groups in the cis position.
Ćelap, Milenko B. +3 more
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Abstract The reactions of alkali hexanitrocobaltates(III) with DL-alanine, D-alanine, L-alanine, and β-alanine have been investigated. Thereby new classes of alkali dinitro-bis (aminoacido)cobaltates(III), M[CoAm 2 (NO 2 ) 2 ] were obtained. It was established that the products obtained contain two nitro groups in the cis position.
Ćelap, Milenko B. +3 more
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Diazenedicarboxamides as inhibitors of d-alanine-d-alanine ligase (Ddl)
Bioorganic & Medicinal Chemistry Letters, 2007D-Alanine-D-alanine ligase (Ddl) catalyzes the biosynthesis of an essential bacterial peptidoglycan precursor D-alanyl-D-alanine and it represents an important target for development of new antibacterial drugs. A series of semicarbazides, aminocarbonyldiazenecarboxylates, diazenedicarboxamides, and hydrazinedicarboxamides was synthesized and screened ...
Andreja, Kovac +7 more
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