Results 381 to 390 of about 897,077 (404)
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Liver alanine catabolism promotes skeletal muscle atrophy and hyperglycaemia in type 2 diabetes
Nature Metabolism, 2021J. Okun +20 more
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Acta Crystallographica Section C Crystal Structure Communications, 2001
A determination of the structure of the title compound, C3H7NO2, leads to an accurate description of its molecular dimensions and crystal packing. As in the structure of the L-isomer, the molecules aggregate into alternating layers, each consisting of only one type of isomer. The molecules in each layer are interconnected through head-to-tail sequences
M, Subha Nandhini +2 more
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A determination of the structure of the title compound, C3H7NO2, leads to an accurate description of its molecular dimensions and crystal packing. As in the structure of the L-isomer, the molecules aggregate into alternating layers, each consisting of only one type of isomer. The molecules in each layer are interconnected through head-to-tail sequences
M, Subha Nandhini +2 more
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Metabolism, 1973
Abstract Alanine is quantitatively the primary amino acid released by muscle and extracted by the splanchnic bed in postabsorptive as well as prolonged fasted man. The hepatic capacity for conversion of alanine to glucose exceeds that of all other amino acids. Insulin inhibits gluconeogenesis by reducing hepatic alanine uptake.
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Abstract Alanine is quantitatively the primary amino acid released by muscle and extracted by the splanchnic bed in postabsorptive as well as prolonged fasted man. The hepatic capacity for conversion of alanine to glucose exceeds that of all other amino acids. Insulin inhibits gluconeogenesis by reducing hepatic alanine uptake.
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Toxicology and Applied Pharmacology, 1976
Abstract Male and female rats of weanling age were fed a basal ration containing 0, 5, 10, or 20% alanine for 26 weeks. When alanine intake increased, urinary alanine increased approximately 100- to 1000-fold and serum alanine increased approximately 50-fold.
Dwayne W. Hamar +4 more
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Abstract Male and female rats of weanling age were fed a basal ration containing 0, 5, 10, or 20% alanine for 26 weeks. When alanine intake increased, urinary alanine increased approximately 100- to 1000-fold and serum alanine increased approximately 50-fold.
Dwayne W. Hamar +4 more
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Biochemical Journal, 2013
Unlike all other organisms, parasitic protozoa of the family Trypanosomatidae maintain a large cellular pool of proline that, together with the alanine pool, serve as alternative carbon sources as well as reservoirs of organic osmolytes.
Ehud Inbar +4 more
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Unlike all other organisms, parasitic protozoa of the family Trypanosomatidae maintain a large cellular pool of proline that, together with the alanine pool, serve as alternative carbon sources as well as reservoirs of organic osmolytes.
Ehud Inbar +4 more
semanticscholar +1 more source
[94c] β-Alanine-α-alanine transaminase (Pseudomonas)
1962Publisher Summary This chapter describes the assay method, isotopic method, purification procedure, and properties of β -Alanine- α - alanine transaminase of Pseudomonas . Enzymatic activity is best determined colorimetrically by testing for malonic semialdehyde.
Yasutomi Nishizuka, Osamu Hayaishi
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Polymerization of
AbstractThe polymerization of N‐carboxy‐DL‐alanine anhydride and N‐carboxy‐L‐alanine anhydride were carried out in various solvents such as acetonitrile, dimethyl sulfoxide (DMSO), and nitrobenzene. The x‐ray diffraction diagram and the infrared spectra of the polymers of DL‐ and L‐alanine were obtained. The polypeptides obtained in acetonitrile and in
Keikichi Uno +2 more
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Glutamine and Alanine Metabolism in NIDDM
Diabetes, 1996Gluconeogenesis is increased in NIDDM. We therefore examined the metabolism of glutamine and alanine, the most important gluconeogenic amino acids, in 14 postabsorptive NIDDM subjects and 18 nondiabetic volunteers using a combination of isotopic ([6-3H] glucose (20 µCi, 0.2 µCi/min), [U-14C]glutamine (20 µCi, 0.2 µCi/min), [3-13C]alanine (99% 13C, 2 ...
Michael Stumvoll +10 more
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Diazenedicarboxamides as inhibitors of d-alanine-d-alanine ligase (Ddl)
Bioorganic & Medicinal Chemistry Letters, 2007D-Alanine-D-alanine ligase (Ddl) catalyzes the biosynthesis of an essential bacterial peptidoglycan precursor D-alanyl-D-alanine and it represents an important target for development of new antibacterial drugs. A series of semicarbazides, aminocarbonyldiazenecarboxylates, diazenedicarboxamides, and hydrazinedicarboxamides was synthesized and screened ...
Andreja, Kovac +7 more
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Rubber Chemistry and Technology, 1934
Abstract INDIRECT evidence of the presence of amino acids in ordinary ammonia-preserved latex was obtained from electrometric titration work with the glass electrode, the application of which to latex was described in a previous article (2). A small sample of alanine has now been isolated and identified, and indication of the presence of
J. McGavack, J. S. Rumbold
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Abstract INDIRECT evidence of the presence of amino acids in ordinary ammonia-preserved latex was obtained from electrometric titration work with the glass electrode, the application of which to latex was described in a previous article (2). A small sample of alanine has now been isolated and identified, and indication of the presence of
J. McGavack, J. S. Rumbold
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