Alanine Aminotransferase to Aspartate Aminotransferase Ratio Measurement [PDF]
, 2020 openaire +1 more source
F13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway
Advanced Science, EarlyView.In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...
Qianrang Lu +16 more
wiley +1 more source
Non-linear association of the alanine aminotransferase to high-density lipoprotein cholesterol ratio with non-alcoholic fatty liver disease: a secondary analysis of a Chinese cohort. [PDF]
Front Med (Lausanne)Lin X, Peng Y, Huang J, Huang Z.
europepmc +1 more source
Advanced Science, EarlyView.To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao +12 more
wiley +1 more source
Abnormal Serum Albumin, Alanine Aminotransferase, and Blood Urea Nitrogen are Associated with Higher Risks for Mechanical Ventilation and In-Hospital Mortality in COVID-19 Positive US Veterans. [PDF]
Biomark InsightsMoss WD +8 more
europepmc +1 more source
Hepatitis B virus genotypes, precore mutations, and basal core promoter mutations in HBV-infected Chinese patients with persistently normal alanine aminotransferase and low serum HBV-DNA levels [PDF]
, 2012 Ming Shi +4 more
openalex +1 more source