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Radioisotopic assay of aspartate and alanine aminotransferase [PDF]
Clinical Biochemistry, 1992 The activities of aspartate and alanine aminotransferases in biological samples were assessed through a novel and sensitive procedure, based on the conversion of [U-14C]2-ketoglutarate to L-[U-14C]glutamate. In human plasma, the generation of L-[U-14C]glutamate was proportional to the volume of plasma (20-60 microL) and to the length of incubation (30 ...
Perales, Miguel Angel +2 more
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A prospective study on the causes of notably raised alanine aminotransferase (ALT)
Scandinavian Journal of Gastroenterology, 2016Helgi K Björnsson +2 more
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Studies on alanine aminotransferase in nematodes
International Journal for Parasitology, 1991L-alanine aminotransferase was demonstrated in a range of gastrointestinal, free-living and entomophagous nematodes. As in mammals, nematode L-alanine aminotransferase was found to exist in the form of mitochondrial and cytosolic isoenzymes. Whilst the majority of nematode enzymes exhibited a greater overall capacity for L-alanine synthesis than for L ...
J, Walker, J, Barrett
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Alanine Aminotransferase Apoenzyme in Dogs
Veterinary Clinical Pathology, 1998Abstract— Unusually low serum activity of alanine aminotransferase (ALT) was detected in a Rottweiler dog with gastric dilatation‐volvulus. Activity of ALT in the same sample was found to be much higher (estimated increase of 14, 225%) when measured by methods adding the cofactor pyridoxal‐5′‐phosphate (P5P), indicating that nearly all serum ALT was in
Christopher I., Mesher +2 more
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Biochemical Medicine, 1980
Abstract The organ distribution of human alanine-2-oxoglutarate aminotransferase and alanine-glyoxylate aminotransferase was investigated. Alanine-2-oxoglutarate aminotransferase was present in all tissues tested (liver, kidney, adrenal gland, brain, pancreas, spleen, jejunum mucosa, testis, lung, heart, and skeletal muscle), and was particularly ...
N, Kamoda +5 more
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Abstract The organ distribution of human alanine-2-oxoglutarate aminotransferase and alanine-glyoxylate aminotransferase was investigated. Alanine-2-oxoglutarate aminotransferase was present in all tissues tested (liver, kidney, adrenal gland, brain, pancreas, spleen, jejunum mucosa, testis, lung, heart, and skeletal muscle), and was particularly ...
N, Kamoda +5 more
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Alanine Aminotransferase and Posttransfusion Hepatitis
JAMA: The Journal of the American Medical Association, 1987To the Editor.— The American Red Cross is initiating the screening of donor blood for high alanine aminotransferase (ALT) levels to reduce the incidence of posttransfusion hepatitis. Non-A, non-B hepatitis, probably caused by several viruses, is the major cause of posttransfusion hepatitis. Thirty percent of patients with posttransfusion hepatitis are
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Alanine Aminotransferase in Clinical Practice
Archives of Internal Medicine, 1991Alanine aminotransferase is an enzyme produced mainly in the liver. When serum activity is measured, it provides a marker of hepatic disease. This review explores the biochemistry and laboratory analysis of alanine aminotransferase in terms of its significance in human health and disease.
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Stability of serum alanine aminotransferase activity
Transfusion, 1987In this study the authors examine the effects of common storage and handling procedures on serum alanine aminotransferase (ALT) levels. Clotted blood samples from 14 subjects were centrifuged at 280 × g for 10 minutes. Serum was tested immediately for baseline ALT levels and aliquots were stored at 22, 4, −20, and −80 ° C. Additional serums were stored
K M, Williams +3 more
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