Results 1 to 10 of about 14,717 (300)
Improved l-Leucine Production in Corynebacterium glutamicum by Optimizing the Aminotransferases
Molecules, 2018 The production of branched-chain amino acids (BCAAs) is still challenging, therefore we rationally engineered Corynebacterium glutamicum FA-1 to increase the l-leucine production by optimizing the aminotransferases.
Li-Yan Feng +2 more
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Crystal structure of L-aspartate aminotransferase from Schizosaccharomyces pombe.
PLoS ONE, 2019 L-aspartate aminotransferase is a pyridoxal 5'-phosphate-dependent transaminase that catalyzes reversible transfer of an α-amino group from aspartate to α-ketoglutarate or from glutamate to oxaloacetate.
Soo Yeon Jeong +2 more
doaj +2 more sources
Molecular and Biochemical Parasitology, 2008 Three genes encoding putative aspartate aminotransferases (ASATs) were identified in the Trypanosoma cruzi genome. Two of these ASAT genes, presumably corresponding to a cytosolic and mitochondrial isoform, were cloned and expressed as soluble His-tagged
Fred R Opperdoes, Cristina Nowicki
exaly +2 more sources
TK2268 encodes the major aminotransferase involved in the conversion from oxaloacetic acid to aspartic acid in Thermococcus kodakarensis [PDF]
Applied and Environmental MicrobiologyAmino acid metabolism in archaea in many cases differs from those reported in bacteria and eukaryotes. The hyperthermophilic archaeon Thermococcus kodakarensis possesses an incomplete tricarboxylic cycle, and the biosynthesis pathway of aspartate is ...
Yu Su +5 more
doaj +2 more sources
International Journal of Preventive Medicine, 2013 Background : Non-alcoholic steatohepatitis (NASH) is a clinicopathological entity that is being recognized more frequently in recent years. This study aimed to evaluate the effects of Metformin, with and without a probiotic supplement on liver ...
Ahmad Shavakhi +5 more
doaj +1 more source
Biomarkers, 2003 In this paper we investigate the potential of glutamate dehydrogenase (GDH) and aspartate and alanine aminotransferases (AST and ALT) as biomarkers of water pollution due to copper in the freshwater snails Helisoma duryi and Lymnaea natalensis.
Y S Naik, Everson Kandare
exaly +3 more sources
Structural Insights into a Novel Class of Aspartate Aminotransferase from Corynebacterium glutamicum. [PDF]
PLoS ONE, 2016 Aspartate aminotransferase from Corynebacterium glutamicum (CgAspAT) is a PLP-dependent enzyme that catalyzes the production of L-aspartate and α-ketoglutarate from L-glutamate and oxaloacetate in L-lysine biosynthesis.
Hyeoncheol Francis Son, Kyung-Jin Kim
doaj +2 more sources
Diabetology & Metabolic Syndrome, 2010 Background Despite ongoing findings on the relationship between elevated levels of alanine and aspartate aminotransferases (ALT and AST) and metabolic syndrome (MetS), this association in diabetic patients without a known cause for liver enzymes ...
Esteghamati Alireza +7 more
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Prospective analysis of 44 consecutive liver transplants performed at a university hospital [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE: To analyze the intraoperative and immediate postoperative biochemical parameters of patients submitted to orthotopic liver transplantation. METHODS: Forty four consecutive orthotopic liver transplants performed from October 2009 to December 2010
Orlando Castro e Silva +7 more
doaj +3 more sources
Journal of Pure and Applied Microbiology, 2023 The use of metallic nanoparticles (NPs) in various industrial and biomedical fields is increasing exponentially. As a result, research examining the potentially toxic impact of these NPs on human health is also increasing. Cytochrome P450 (P450s) enzymes
Hayat A. Al-Btoush
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