Results 41 to 50 of about 14,808 (300)

Hepato-Protective Effects of Silymarin and Coffee in Rats

Journal of Islamic International Medical College, 2021
Objective: To compare the effects of silymarin and coffee on liver enzymes in acetaminophen-induced hepatotoxicity in rats. Study Design: Experimental-randomized control study.
Sidra Mumal, Akbar Waheed, Abdul Azeem, Hira Waqas Cheema, Fakhra Noureen, Abeera Zainab
doaj  

Transaminases activity in the sand lizard’s serum under influence of industrial pollution

Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2009
Influence of the environmental pollution on the alanine aminotransferase and aspartate aminotransferase activity in the blood serum of the sand lizard has been studied. Aminotransferases (ALT and AST) are similar by the mechanism of action. These enzymes
O. Y. Klymenko, V. Y. Gasso
doaj   +1 more source

AST·MLR index and operation injury condition are novel prognostic predictor for the prediction of survival in patients with colorectal cancer liver metastases undergoing surgical resection

BMC Cancer, 2022
Background The prognostic values of preoperative aspartate aminotransferase (AST), monocyte-to-lymphocyte ratio (MLR), AST·MLR index (AMLRI) and operation injury condition in patients with colorectal cancer liver metastases (CRLM) remains unclear.
Qichen Chen, Mingxia Li, Jinghua Chen, Zhen Huang, Xiao Chen, Hong Zhao, Jianqiang Cai   +6 more
doaj   +1 more source

Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina [PDF]

, 2001
In this study aminotransferase inhibitors were used to determine the relative importance of different aminotransferases in providing nitrogen for de novo glutamate synthesis in the retina. Aminooxyacetate, which inhibits all aminotransferases, blocked de
Conway, Myra E., Hutson, Susan M., Charles Taylor, Kathyrn F. LaNoue, Myra Conway, LaNoue, K.F., Barber, A.J., Berkich, D.A., Hu, L.Y., Alistair J. Barber, Taylor, C., Lain‐Yen Hu, Deborah A. Berkich, Susan Hutson   +13 more
core   +1 more source

Liver enzyme elevation in patients with ankylosing spondylitis treated with tumor necrosis factor inhibitors: a single-center historical cohort study [PDF]

The Korean Journal of Internal Medicine, 2020
Background/Aims Tumor necrosis factor inhibitors (TNFi) have been known to induce liver enzyme elevation, sometimes associated with viral reactivation or toxic hepatitis.
Su Jin Choi, Ji Seon Oh, Seokchan Hong, Chang-Keun Lee, Bin Yoo, Yong-Gil Kim   +5 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Mitochondrial bovine aspartate aminotransferase. Preliminary sequence and crystallographic data. [PDF]

, 1979
Cytosolic aspartate aminotransferase (EC 2.6.1.1) from ox heart has been fully characterized; the most significant results have been reviewed. An investigation is now in progress to establish structural and evolutionary relationships between this enzyme ...
MAZZARELLA, LELIO, SANNIA, GIOVANNI, PUCCI, PIETRO, Capasso S, MARINO, GENNARO, Garzillo AM   +5 more
core   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Liver and erythrocyte L-aspartate: and L-alanine: 2-oxoglutarate aminotransferases of the pyridoxine deficient rat. [PDF]

, 1968
The withdrawal of pyridoxine from the diet of male weading rats did not appear to affect the liver mitochondrial L-aspartate : 2-oxoglutarate amhotransferase, but the ismnzymes in the liver supematant and in the erythrocyte showed gradual lowering of ...
Radhakrishnamurthy, R., Sabry, Z. I.
core