Photoinactivation of Aspartate Aminotransferase
Abstract The cofactor pyridoxal 5'-phosphate bound through an aldimine linkage to lysine residues of the enzyme aspartate aminotransferase is very stable to irradiation with light of 420 nm. The catalytic function of the enzyme exposed to light absorbed by the cofactor remains unaffected, indicating that pyridoxal 5'-phosphate is not an efficient ...
N, Burridge, J E, Churchich
openaire +2 more sources
Principles of reptile treatment are significantly different from the drug therapy for mammals and birds, which is primarily due to anatomical and physiological peculiarities of reptiles.
R. S. Dankovych, V. I. Chuliuk
doaj +1 more source
Liver enzymes, metabolomics and genome-wide association studies: From systems biology to the personalized medicine. [PDF]
For several decades, serum levels of alanine (ALT) and aspartate (AST) aminotransferases have been regarded as markers of liver injury, including a wide range of etiologies from viral hepatitis to fatty liver.
Pirola, Carlos José +1 more
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Aspartate aminotransferase/alanine aminotransferase ratio and subsequent cancer development [PDF]
AbstractBackgroundWe aimed to evaluate the association between the aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ratio and subsequent development of any type of cancer in an apparently healthy population.MethodsWe conducted a retrospective cohort study at St. Luke's International Hospital, Tokyo, Japan between 2005 and 2018.
Daiki Kobayashi +3 more
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Preventive effects of Prangos ferulacea (L.) Lindle on liver damage of diabetic rats induced by alloxan [PDF]
Objectives: Diabetes mellitus is associated with biochemical, physiological and pathological alterations in the liver. The aim of this study was to investigate the effects of hydroalcoholic extract of Prangos ferulacea (L.) Lindle (P.f) on changes in ...
Farah Farokhi +3 more
doaj
Serum γ-glutamyltransferase, alanine aminotransferase and aspartate aminotransferase activity in healthy blood donor of different ethnic groups in Gorgan [PDF]
Introduction: Measure of liver enzymes may help to increase safety of blood donation for both blood donor and recipient. Determination of liver enzymes may prepare valuable clinical information.
Marjani, A. +2 more
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Background The prognostic values of preoperative aspartate aminotransferase (AST), monocyte-to-lymphocyte ratio (MLR), AST·MLR index (AMLRI) and operation injury condition in patients with colorectal cancer liver metastases (CRLM) remains unclear.
Qichen Chen +6 more
doaj +1 more source
Robust reference intervals for Liver function test (LFT) analytes in newborns and infants [PDF]
BACKGROUND: Reference intervals (RIs) are ranges of upper and lower limits of a given analyte which are used for a laboratory test to determine whether a disease is present or absent or to know if the patient is at risk for future disease states.
Mahilet Yigeremu +6 more
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Hepato-Protective Effects of Silymarin and Coffee in Rats
Objective: To compare the effects of silymarin and coffee on liver enzymes in acetaminophen-induced hepatotoxicity in rats. Study Design: Experimental-randomized control study.
Sidra Mumal, Akbar Waheed, Abdul Azeem, Hira Waqas Cheema, Fakhra Noureen, Abeera Zainab
doaj
Transaminases activity in the sand lizard’s serum under influence of industrial pollution
Influence of the environmental pollution on the alanine aminotransferase and aspartate aminotransferase activity in the blood serum of the sand lizard has been studied. Aminotransferases (ALT and AST) are similar by the mechanism of action. These enzymes
O. Y. Klymenko, V. Y. Gasso
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