Results 41 to 50 of about 14,717 (300)
The active site of Sulfolobus solfataricus aspartate aminotransferase
, 1991 Aspartate aminotransferase from the archaebacterium Sulfolobus solfataricus binds pyridoxal 5' phosphate, via an aldimine bond, with Lys-241. This residue has been identified by reducing the enzyme in the pyridoxal form with sodium cyanoboro[H-3]hydride ...
SANNIA, GIOVANNI +6 more
core +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Occurrence and distribution of aspartate aminotransferases in spruce and beech ectomycorrhizas
, 1990 Activities and localization of aspartate aminotransferases (AAT) were determined in spruce and beech ectomycorrhizas, as well as in nonmycorrhizal roots and fungi in pure culture. Preliminary data emphasized the importance of AAT in amino acid synthesis;
Michel Chalot +5 more
core +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Macro-aspartate aminotransferase in a healthy woman [PDF]
Clinical and Molecular Hepatology, 2020 An increase in serum aspartate aminotransferase (AST) may be related to different conditions, including viral hepatitis, alcoholic liver disease, cirrhosis, cholestatic syndromes, acute myocardial infarction, or skeletal muscle trauma [1]. Chronic and isolated elevation of AST in patients with no related clinical signs or symptoms is suggestive for the
Lorubbio M. +4 more
openaire +3 more sources
Arthritis Care &Research, EarlyView.Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns +2 more
wiley +1 more source
Effect of Temperature and storage time on Hepatobiliary enzyme activities in Goat serum [PDF]
Veterinary World, 2010 The present study was designed and conducted to choose an ideal storage condition for goat sera samples meant for the assay of hepatobiliary enzymes such as, alanine aminotransferases(ALT), aspartate aminotransferases (AST), alkaline phosphatase (ALP ...
P.D. Divya and K.K. Jayavardhanan
doaj
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
BMC Endocrine Disorders, 2019 Background Abnormal levels of liver enzymes, particularly aminotransferases, are prognostic features of non-alcoholic fatty liver disease (NAFLD). Considering the important role of dietary intakes in development of NAFLD, we aimed to determine possible ...
Parvin Mirmiran +3 more
doaj +1 more source
Pretreatment of hepatetctomized rats with Coleus forskohlii did not interfere with the course of hepatic hyperplasia [PDF]
Acta Cirúrgica Brasileira, 2019 Purpose Coleus forskohlii Briq., a medicinal plant originally from India, has been indicated against heart disease, expiratory disorders, convulsions, and hepatic changes, among others.
Pedro Paulo Barros +3 more
doaj +1 more source