Results 61 to 70 of about 85,064 (291)
The active site of Sulfolobus solfataricus aspartate aminotransferase
Aspartate aminotransferase from the archaebacterium Sulfolobus solfataricus binds pyridoxal 5' phosphate, via an aldimine bond, with Lys-241. This residue has been identified by reducing the enzyme in the pyridoxal form with sodium cyanoboro[H-3]hydride ...
SANNIA, GIOVANNI +6 more
core +1 more source
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão +5 more
wiley +1 more source
Background: Carbon tetrachloride (CCl4) as an organic solvent causes symptoms of acute and chronic liver injury, including necrosis, fat changes, liver cancer, and cirrhosis.
Mohammad Shokrzadeh +4 more
doaj
Structural Insights into a Novel Class of Aspartate Aminotransferase from Corynebacterium glutamicum. [PDF]
Aspartate aminotransferase from Corynebacterium glutamicum (CgAspAT) is a PLP-dependent enzyme that catalyzes the production of L-aspartate and α-ketoglutarate from L-glutamate and oxaloacetate in L-lysine biosynthesis.
Hyeoncheol Francis Son, Kyung-Jin Kim
doaj +1 more source
INTERACTION OF ASPARTATE AMINOTRANSFERASE WITH AMINO ACIDS [PDF]
1. The capacity of various amino acids to convert the pyridoxal form of aspartate aminotransferase into the pyridoxamine form has been investigated. 2. Glutamate has the highest converting capacity; aspartate, alpha-aminopimelate, alpha-aminoadipate and other amino acids follow. 3. The converting capacity of the various amino acids assayed is connected
P, SCOTTO, V, SCARDI
openaire +2 more sources
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song +14 more
wiley +1 more source
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi +5 more
wiley +1 more source
Objetivou-se determinar o perfil da aspartato aminotransferase e alanina aminotransferase e a biometria do fígado de codornas poedeiras (Coturnix coturnix japonica) de 1 a 25 dias de idade.
Anderson de Almeida Barbosa +5 more
doaj +1 more source
Occurrence and distribution of aspartate aminotransferases in spruce and beech ectomycorrhizas
Activities and localization of aspartate aminotransferases (AAT) were determined in spruce and beech ectomycorrhizas, as well as in nonmycorrhizal roots and fungi in pure culture. Preliminary data emphasized the importance of AAT in amino acid synthesis;
Michel Chalot +5 more
core +1 more source

