Results 1 to 10 of about 452,969 (207)
eLife, 2018 Drugs called bisphosphonates are used to treat a range of bone diseases, but how do they reach the enzymes that are their target?
Michael J Rogers, Marcia A Munoz
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Sensing microbial RNA in the cytosol [PDF]
Frontiers in Immunology, 2013 The innate immune system faces the difficult task of keeping a fine balance between sensitive detection of microbial presence and avoidance of autoimmunity.
Nicolas eVABRET, Julie Magarian eBlander
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Endoplasmic Reticulum Calcium Regulates the Retrotranslocation of Trypanosoma Cruzi Calreticulin to the Cytosol [PDF]
PLoS ONE, 2010 For most secretory pathway proteins, crossing the endoplasmic reticulum (ER) membrane is an irreversible process. However, in some cases this flow can be reversed.
Ianina Conté, Armando J Parodi
exaly +2 more sources
Co-cultured methanogen improved the metabolism in the hydrogenosome of anaerobic fungus as revealed by gas chromatography-mass spectrometry analysis [PDF]
Asian-Australasian Journal of Animal Sciences, 2020 Objective The purpose of this study was to reveal the metabolic shift in the fungus co-cultured with the methanogen (Methanobrevibacter thaueri). Methods Gas chromatography-mass spectrometry was used to investigate the metabolites in anaerobic fungal ...
Yuqi Li +4 more
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Microorganisms, 2022 Voltage-dependent anion-selective channels (VDAC) maintain the bidirectional flow of small metabolites across the mitochondrial outer membrane and participate in the regulation of multiple cellular processes.
Sabbir R. Shuvo +4 more
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Metabolites, 2021 Direct injury of mitochondrial respiratory chain (RC) complex I by Ndufs4 subunit mutations results in complex I deficiency (CID) and a progressive encephalomyopathy, known as Leigh syndrome.
Gunter van der Walt +3 more
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Simple and Efficient Protocol for Subcellular Fractionation of Normal and Apoptotic Cells
Cells, 2021 Subcellular fractionation approaches remain an indispensable tool among a large number of biochemical methods to facilitate the study of specific intracellular events and characterization of protein functions.
Viacheslav V. Senichkin +3 more
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Ser-Thr phosphatases in the rat brain that dephosphorylate phospho-Ser(1291)-GluN2A subunit of glutamate receptor [PDF]
The Ukrainian Biochemical Journal, 2023 N-methyl-D-aspartate receptors (NMDARs), are one of the major ionotropic glutamate receptors found in excitatory synapses which play a key role in glutamatergic synaptic transmission.
R. R. Prabhu
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Size of the protein-protein energy funnel in crowded environment
Frontiers in Molecular Biosciences, 2022 Association of proteins to a significant extent is determined by their geometric complementarity. Large-scale recognition factors, which directly relate to the funnel-like intermolecular energy landscape, provide important insights into the basic rules ...
Nathan W. Jenkins +3 more
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Frontiers in Physics, 2023 A colloidal particle placed inside the cell cytoplasm is enmeshed within a network of cytoskeletal fibres immersed in the cytosolic fluid. The translational mode is believed to yield different rheological parameters than the rotational mode, given that ...
Srestha Roy +6 more
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