Results 31 to 40 of about 323,927 (286)

Overexpression of the transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion

open access: yesMicrobial Cell, 2014
Oxidative folding of secretory proteins in the endoplasmic reticulum (ER) is a redox active process, which also impacts the redox conditions in the cytosol. As the transcription factor Yap1 is involved in the transcriptional response to oxidative stress,
Marizela Delic   +6 more
doaj   +1 more source

Heat-Induced Oxidation of the Nuclei and Cytosol

open access: yesFrontiers in Plant Science, 2021
The concept that heat stress (HS) causes a large accumulation of reactive oxygen species (ROS) is widely accepted. However, the intracellular compartmentation of ROS accumulation has been poorly characterized.
Richa Babbar   +4 more
doaj   +1 more source

Micrometer-Scale Membrane Transition of Supported Lipid Bilayer Membrane Reconstituted with Cytosol of Dictyostelium discoideum

open access: yesLife, 2017
Background: The transformation of the supported lipid bilayer (SLB) membrane by extracted cytosol from living resources, has recently drawn much attention. It enables us to address the question of whether the purified phospholipid SLB membrane, including
Kei Takahashi, Taro Toyota
doaj   +1 more source

On the Origin and Fate of Reactive Oxygen Species in Plant Cell Compartments

open access: yesAntioxidants, 2019
Reactive oxygen species (ROS) have been recognized as important signaling compounds of major importance in a number of developmental and physiological processes in plants.
Martina Janků   +2 more
doaj   +1 more source

Emerging Roles of Long Noncoding RNAs in the Cytoplasmic Milieu

open access: yesNon-Coding RNA, 2020
While the important functions of long noncoding RNAs (lncRNAs) in nuclear organization are well documented, their orchestrating and architectural roles in the cytoplasmic environment have long been underestimated.
Michelle Aillaud, Leon N Schulte
doaj   +1 more source

Cytosolic Prion Protein in Neurons [PDF]

open access: yesThe Journal of Neuroscience, 2003
Localizing the cellular prion protein (PrPC) in the brain is necessary for understanding the pathogenesis of prion diseases. However, the precise ultrastructural localization of PrPC still remains enigmatic. We performed the first quantitative study of the ultrastructural localization of PrPC in the mouse hippocampus using high-resolution ...
Mironov, A.   +9 more
openaire   +3 more sources

Intracellular niche-specific profiling reveals transcriptional adaptations required for the cytosolic lifestyle of Salmonella enterica.

open access: yesPLoS Pathogens, 2021
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a zoonotic pathogen that causes diarrheal disease in humans and animals. During salmonellosis, S. Typhimurium colonizes epithelial cells lining the gastrointestinal tract. S.
TuShun R Powers   +8 more
doaj   +1 more source

Simulations on an undamped electromechanical vibration of microtubules in cytosol [PDF]

open access: yes, 2019
This letter aims to study the electromechanical vibration of microtubules submerged in cytosol. The microtubule-cytosol interface is established in molecular dynamics simulations, and the electrically excited vibrations of microtubules in cytosol are ...
Si Li   +2 more
core   +1 more source

Protein Phosphatase 1 inactivates Mps1 to ensure efficient Spindle Assembly Checkpoint silencing

open access: yeseLife, 2017
Faithfull genome partitioning during cell division relies on the Spindle Assembly Checkpoint (SAC), a conserved signaling pathway that delays anaphase onset until all chromosomes are attached to spindle microtubules.
Margarida Moura   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy