Results 21 to 30 of about 323,927 (286)

Purification of Mg2+-dependent phosphatidate phosphohydrolase from rat liver: new steps and aspects [PDF]

, 2005
A new procedure for the partial purification of Mg2+-dependent, N-ethylmaleimide-sensitive phosphatidate phosphohydrolase (Mg2+-PAP; EC 3.1.3.4) from rat liver cytosol is described, using protein precipitation with MgCl2, gel filtration on Sephacryl S ...
Hofstetter, Monika M., Siess, Elmar A.
core   +1 more source

Calciprotein Particles Induce Cellular Compartment-Specific Proteome Alterations in Human Arterial Endothelial Cells

Journal of Cardiovascular Development and Disease, 2023
Calciprotein particles (CPPs) are indispensable scavengers of excessive Ca2+ and PO43− ions in blood, being internalised and recycled by liver and spleen macrophages, monocytes, and endothelial cells (ECs).
Daria Shishkova, Arseniy Lobov, Egor Repkin, Victoria Markova, Yulia Markova, Anna Sinitskaya, Maxim Sinitsky, Egor Kondratiev, Evgenia Torgunakova, Anton Kutikhin   +9 more
doaj   +1 more source

Cytosolic Sensing of Viruses [PDF]

Immunity, 2013
Cells are equipped with mechanisms that allow them to rapidly detect and respond to viruses. These defense mechanisms rely partly on receptors that monitor the cytosol for the presence of atypical nucleic acids associated with virus infection. RIG-I-like receptors detect RNA molecules that are absent from the uninfected host.
Goubau, Delphine, Deddouche, Safia, Reis e Sousa, Caetano   +2 more
openaire   +2 more sources

Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways [PDF]

, 2011
Background: The small molecule Eeyarestatin I (ESI) inhibits the endoplasmic reticulum (ER)-cytosol dislocation and subsequent degradation of ERAD (ER associated protein degradation) substrates.
Aletrari, Mina-Olga, Roger Whitehead, Helen Williams, Whitehead, Roger C., Robert A. Spooner, Flitsch, Sabine L., Swanton, Eileithyia, Stephen High, Pietroni, Paola, Eileithyia Swanton, Whitehead, Roger, Vidya Pawar, Sabine L. Flitsch, Sabine L Flitsch, Paola Pietroni, High, Stephen; id_orcid, J Michael Lord, Spooner, Robert A., Lord, J. Michael, McKibbin, Craig, Pawar, Vidya, Williams, Helen, Lord, Mike, Mina-Olga Aletrari, Robert A Spooner, Craig McKibbin, High, Stephen, J. Michael Lord, Aletrari, Mina Olga   +28 more
core   +2 more sources

Salmonella Populations inside Host Cells

Frontiers in Cellular and Infection Microbiology, 2017
Bacteria of the Salmonella genus cause diseases ranging from gastroenteritis to life-threatening typhoid fever and are among the most successful intracellular pathogens known.
Sónia Castanheira, Francisco García-del Portillo   +1 more
doaj   +1 more source

Dissecting the Role of SAL1 in Metabolizing the Stress Signaling Molecule 3′-Phosphoadenosine 5′-Phosphate in Different Cell Compartments

Frontiers in Molecular Biosciences, 2022
Plants possess the most highly compartmentalized eukaryotic cells. To coordinate their intracellular functions, plastids and the mitochondria are dependent on the flow of information to and from the nuclei, known as retrograde and anterograde signals ...
Natallia Ashykhmina, Kai Xun Chan, Kai Xun Chan, Henning Frerigmann, Frank Van Breusegem, Frank Van Breusegem, Stanislav Kopriva, Ulf-Ingo Flügge, Tamara Gigolashvili   +8 more
doaj   +1 more source

The Mechanisms of Tau Entry to the Cytosol [PDF]

, 2022
The microtubule associated protein tau forms filamentous assemblies in the cytosol of neurons in several neurodegenerative diseases. In Alzheimer’s disease, tau pathology arises throughout the human brain in a spatio-temporal manner and closely ...

core   +2 more sources

Minimizing Cytosol Dilution in Whole-Cell Patch-Clamp Experiments [PDF]

, 2013
During a conventional whole-cell patch clamp experiment, diffusible cytosolic ions or molecules absent in the pipette solution can become diluted by a factor of one million or more, leading to diminished current or fluorescent signals.
Samsoon Inayat (8002145), Lawrence H. Pinto (188613), John B. Troy (8002148)   +2 more
core   +6 more sources

Folding-competent and folding-defective forms of Ricin A chain have different fates following retrotranslocation from the endoplasmic reticulum [PDF]

, 2010
We report that a toxic polypeptide retaining the potential to refold upon dislocation from the endoplasmic reticulum (ER) to the cytosol (ricin A chain; RTA) and a misfolded version that cannot (termed RTAΔ), follow ER-associated degradation (ERAD ...
Ladds, Graham, Manfred J. Schmitt, Robert A. Spooner, Stuart C. H. Allen, Schmitt, Manfred J., Shuyu Li, Christopher P. Guise, Lord, J M, Allen, Stuart C. H., Li, Shuyu, Roberts, L. M. (Lynne M.), Allen, Stuart C H, Schnöder, Tina, Spooner, R A, Spooner, Robert A., Ladds, G, Roberts, R M, Tina Schnöder, Guise, C P, Schmitt, M J, Guise, Christopher P., Graham Ladds, Lord, Mike, Lynne M. Roberts, J. Michael Lord, Li, S, Schnoder, T   +26 more
core   +1 more source

The activity of NADH-, NADPH- and Fd-dependent glutamate synthase in the plastids and cytosol of Pisum arvense L. root cells

Acta Societatis Botanicorum Poloniae, 2014
Three forms of glutamate synthase (NADH-GOGAT, NADPH-GOGAT and Fd-(ferredoxin) GOGAT) were found in the plastids and cytosol of Pisum arvense root cells.
Genowefa Kubik-Dobosz
doaj   +1 more source