Results 21 to 30 of about 389,979 (247)

Size of the protein-protein energy funnel in crowded environment

Frontiers in Molecular Biosciences, 2022
Association of proteins to a significant extent is determined by their geometric complementarity. Large-scale recognition factors, which directly relate to the funnel-like intermolecular energy landscape, provide important insights into the basic rules ...
Nathan W. Jenkins, Petras J. Kundrotas, Ilya A. Vakser, Ilya A. Vakser   +3 more
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The boundary of life and death: changes in mitochondrial and cytosolic proteomes associated with programmed cell death of Arabidopsis thaliana suspension culture cells

Frontiers in Plant Science, 2023
IntroductionDespite the critical role of programmed cell death (PCD) in plant development and defense responses, its regulation is not fully understood.
Johanna Schwarze, James C. Carolan, Gavin S. Stewart, Paul F. McCabe, Joanna Kacprzyk   +4 more
doaj   +1 more source

Trehalose as a Stabilizer of the Lipid Composition of Membranes and the Composition of the Cytosol of Frozen/Thawed Rooster Spermatozoa

Agriculture, 2023
Low-temperature semen storage technologies are already being used in poultry conservation programs, but the quality of reproductive material stored in cryobanks varies greatly and cannot always be successfully used for practical purposes.
Olga Stanishevskaya, Yulia Silyukova, Vera Tereshina, Elena Ianutsevich, Nikolai Pleshanov, Anton Kurochkin, Elena Fedorova   +6 more
doaj   +1 more source

Molecular cloning and characterization of nitrogen source responsive GS1 gene from melon

Biologia Plantarum, 2011
A full-length cDNA clone encoding cytosolic glutamine synthetase (GS1; EC 6.3.1.2) was isolated from melon (Cucumis melo L.) for the first time by RT-PCR and RACE approach. The clone, designated as M-GS1 (accession No.
Y. -W. Deng, Y. -D. Zhang, S. -Q. Guan, Y. Chen, W. Jiang, D. -M. Tang, D. -F. Huang   +6 more
doaj   +1 more source

The Mechanisms of Tau Entry to the Cytosol [PDF]

, 2022
The microtubule associated protein tau forms filamentous assemblies in the cytosol of neurons in several neurodegenerative diseases. In Alzheimer’s disease, tau pathology arises throughout the human brain in a spatio-temporal manner and closely ...

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Influence of Technological Stages of Preparation of Rooster Semen for Short-Term and Long-Term Storage on Its Quality Characteristics

Current Issues in Molecular Biology, 2022
There is a problem of declining quality of rooster semen in the “native semen-equilibrium-short-term and long-term storage (cryopreservation)” cycle. The aim of this study was to determine the effects of various methods of preparing rooster semen on its ...
Yulia Silyukova, Elena Fedorova, Olga Stanishevskaya   +2 more
doaj   +1 more source

Cytosolic entry of Shiga-like toxin A chain from the yeast endoplasmic reticulum requires catalytically active Hrd1p [PDF]

, 2012
Background Escherichia coli Shiga-like toxin 1 normally traffics to the endoplasmic reticulum (ER) in sensitive mammalian cells from where the catalytic A chain (SLTxA1) dislocates to the cytosol to inactivate ribosomes.
Lynne M. Roberts (150050), J Michael Lord, Roberts Lynne M., Spooner, Robert A., Hampton Randolph Y., Lord J. Michael, Robert A. Spooner (150027), Spooner Robert A., Lord, J. Michael, Shuyu Li (18735), Roberts, Lynne M., Randolph Y Hampton, Lynne M Roberts, Shuyu Li, Lord, Mike, J. Michael Lord (150042), Li, Shuyu, Roberts, L. M. (Lynne M.), Robert A Spooner, Randolph Y. Hampton (150034), Li Shuyu, Hampton, Randolph Y.   +21 more
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Calciprotein Particles Induce Cellular Compartment-Specific Proteome Alterations in Human Arterial Endothelial Cells

Journal of Cardiovascular Development and Disease, 2023
Calciprotein particles (CPPs) are indispensable scavengers of excessive Ca2+ and PO43− ions in blood, being internalised and recycled by liver and spleen macrophages, monocytes, and endothelial cells (ECs).
Daria Shishkova, Arseniy Lobov, Egor Repkin, Victoria Markova, Yulia Markova, Anna Sinitskaya, Maxim Sinitsky, Egor Kondratiev, Evgenia Torgunakova, Anton Kutikhin   +9 more
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Purification of Mg2+-dependent phosphatidate phosphohydrolase from rat liver: new steps and aspects [PDF]

, 2005
A new procedure for the partial purification of Mg2+-dependent, N-ethylmaleimide-sensitive phosphatidate phosphohydrolase (Mg2+-PAP; EC 3.1.3.4) from rat liver cytosol is described, using protein precipitation with MgCl2, gel filtration on Sephacryl S ...
Hofstetter, Monika M., Siess, Elmar A.
core   +1 more source

Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways [PDF]

, 2011
Background: The small molecule Eeyarestatin I (ESI) inhibits the endoplasmic reticulum (ER)-cytosol dislocation and subsequent degradation of ERAD (ER associated protein degradation) substrates.
Aletrari, Mina-Olga, Roger Whitehead, Helen Williams, Whitehead, Roger C., Robert A. Spooner, Flitsch, Sabine L., Swanton, Eileithyia, Stephen High, Pietroni, Paola, Eileithyia Swanton, Whitehead, Roger, Vidya Pawar, Sabine L. Flitsch, Sabine L Flitsch, Paola Pietroni, High, Stephen; id_orcid, J Michael Lord, Spooner, Robert A., Lord, J. Michael, McKibbin, Craig, Pawar, Vidya, Williams, Helen, Lord, Mike, Mina-Olga Aletrari, Robert A Spooner, Craig McKibbin, High, Stephen, J. Michael Lord, Aletrari, Mina Olga   +28 more
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