Results 21 to 30 of about 453,068 (302)

Dissecting the Role of SAL1 in Metabolizing the Stress Signaling Molecule 3′-Phosphoadenosine 5′-Phosphate in Different Cell Compartments

Frontiers in Molecular Biosciences, 2022
Plants possess the most highly compartmentalized eukaryotic cells. To coordinate their intracellular functions, plastids and the mitochondria are dependent on the flow of information to and from the nuclei, known as retrograde and anterograde signals ...
Natallia Ashykhmina, Kai Xun Chan, Kai Xun Chan, Henning Frerigmann, Frank Van Breusegem, Frank Van Breusegem, Stanislav Kopriva, Ulf-Ingo Flügge, Tamara Gigolashvili   +8 more
doaj   +1 more source

Functional Characterization of the Eukaryotic Cysteine Desulfurase Nfs1p from Saccharomyces cerevisiae [PDF]

, 2004
Previous studies have indicated that the essential protein Nfs1 performs a crucial role in cellular iron-sulfur (Fe/S) protein maturation. The protein is located predominantly in mitochondria, yet low amounts are present in cytosol and nucleus.
Balk, Balk, Cupp-Vickery, Diekert, Dutkiewicz, Floss, Frazzon, Frazzon, Garland, Gerber, Gerber, Gietz, Gyula Kispal, Harlow, Hoff, Janneke Balk, Jaschkowitz, Jens T. Kaiser, Kaiser, Kambampati, Kambampati, Katalin Sipos, Kaut, Kim, Kispal, Knight, Knight, Knox, Kolman, Land, Lange, Lange, Lauhon, Leibrecht, Leipuviene, Li, Lill, Matthies, Meyer, Mihara, Mühlenhoff, Mühlenhoff, Mühlenhoff, Nachin, Nadine Richhardt, Nakai, Nakai, Nett, Nilsson, Outten, Papenbrock, Pierrel, Roland Lill, Roy, Sambrook, Schilke, Schwartz, Sherman, Silberg, Sipos, Skovran, Stein, Strain, Takahashi, Tong, Tong, Ulrich Mühlenhoff, Ungermann, Voisine, Wang, Yuvaniyama, Zheng, Zheng, Zheng   +73 more
core   +3 more sources

Cytosolic Sensing of Viruses [PDF]

Immunity, 2013
Cells are equipped with mechanisms that allow them to rapidly detect and respond to viruses. These defense mechanisms rely partly on receptors that monitor the cytosol for the presence of atypical nucleic acids associated with virus infection. RIG-I-like receptors detect RNA molecules that are absent from the uninfected host.
Goubau, Delphine, Deddouche, Safia, Reis e Sousa, Caetano   +2 more
openaire   +2 more sources

Micrometer-Scale Membrane Transition of Supported Lipid Bilayer Membrane Reconstituted with Cytosol of Dictyostelium discoideum

Life, 2017
Background: The transformation of the supported lipid bilayer (SLB) membrane by extracted cytosol from living resources, has recently drawn much attention. It enables us to address the question of whether the purified phospholipid SLB membrane, including
Kei Takahashi, Taro Toyota
doaj   +1 more source

How are proteins reduced in the endoplasmic reticulum? [PDF]

, 2018
The reversal of thiol oxidation in proteins within the endoplasmic reticulum (ER) is crucial for protein folding, degradation, chaperone function, and the ER stress response. Our understanding of this process is generally poor but progress has been made.
Bulleid, Neil, Ellgaard, Lars, Sevier, Carolyn S.   +2 more
core   +2 more sources

On the Origin and Fate of Reactive Oxygen Species in Plant Cell Compartments

Antioxidants, 2019
Reactive oxygen species (ROS) have been recognized as important signaling compounds of major importance in a number of developmental and physiological processes in plants.
Martina Janků, Lenka Luhová, Marek Petřivalský   +2 more
doaj   +1 more source

Explicit consideration of topological and parameter uncertainty gives new insights into a well-established model of glycolysis [PDF]

, 2013
Previous models of glycolysis in the sleeping sickness parasite Trypanosoma brucei assumed that the core part of glycolysis in this unicellular parasite is tightly compartimentalized within an organelle, the glycosome, which had previously been shown to ...
Achcar, Albert, Bakker, Bakker, Bakker, Bakker, Blattner, Chevalier, Clarkson, Clarkson, Cronín, Fairlamb, Fairlamb, Gualdron-López, Gualdrón-López, Guerra-Giraldez, Haanstra, Haanstra, Hammond, Helfert, Häusler, Michels, Miškovíc, Murabito, Opperdoes, Rizk, Satish Kumar, Steiger, Tran, Visser, Wang   +30 more
core   +1 more source

Heat-Induced Oxidation of the Nuclei and Cytosol

Frontiers in Plant Science, 2021
The concept that heat stress (HS) causes a large accumulation of reactive oxygen species (ROS) is widely accepted. However, the intracellular compartmentation of ROS accumulation has been poorly characterized.
Richa Babbar, Richa Babbar, Barbara Karpinska, Anil Grover, Christine H. Foyer   +4 more
doaj   +1 more source

Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum [PDF]

, 2008
The plant cytotoxin ricin enters target mammalian cells by receptor-mediated endocytosis and undergoes retrograde transport to the endoplasmic reticulum (ER).
R. A. Spooner, P. J. Hart, J. P. Cook, P. Pietroni, C. Rogon, J. Hohfeld, L. M. Roberts, J. M. Lord, Brodsky, Meusser, Spooner, Wesche, Argent, van Deurs, Rapak, Wales, Meacham, Brodsky, Hudson, Roe, Lawson, Argent, Savino, Chaddock, Chen, Luders, H  hfeld, Urushitani, Younger, Arndt, Nakatsukasa, Nakatsukasa, Hundley   +32 more
core   +3 more sources

Salmonella Populations inside Host Cells

Frontiers in Cellular and Infection Microbiology, 2017
Bacteria of the Salmonella genus cause diseases ranging from gastroenteritis to life-threatening typhoid fever and are among the most successful intracellular pathogens known.
Sónia Castanheira, Francisco García-del Portillo   +1 more
doaj   +1 more source