Results 31 to 40 of about 221,538 (343)

Lycopene and resveratrol pretreatment did not interfere with the liver of hepatectomized rats [PDF]

Acta Cirúrgica Brasileira, 2017
Purpose: To investigate the effects of lycopene and resveratrol pretreatment on hepatic hyperplasia in partially hepatectomized rats. Methods: The lycopene group and the resveratrol group received 40 mg/kg/day of lycopene or resveratrol, respectively ...
Pedro Paulo Barros, Gisele Mara Silva Gonçalves, Gustavo Henrique da Silva, Maria Clara Villaça Dias Bastos, Loren Nogaroto Ramos, Marilia Marinello Fernandes   +5 more
doaj   +1 more source

Empagliflozin is associated with improvements in liver enzymes potentially consistent with reductions in liver fat: results from randomised trials including the EMPA-REG OUTCOME® trial [PDF]

, 2018
Aims/hypothesis: In addition to beneficial effects on glycaemia and cardiovascular death, empagliflozin improves adiposity indices. We investigated the effect of empagliflozin on aminotransferases (correlates of liver fat) in individuals with type 2 ...
Fitchett, David, George, Jyothis T., Hantel, Stefan, Sattar, Naveed, Zinman, Bernard   +4 more
core   +1 more source

Improved l-Leucine Production in Corynebacterium glutamicum by Optimizing the Aminotransferases

Molecules, 2018
The production of branched-chain amino acids (BCAAs) is still challenging, therefore we rationally engineered Corynebacterium glutamicum FA-1 to increase the l-leucine production by optimizing the aminotransferases.
Li-Yan Feng, Jian-Zhong Xu, Wei-Guo Zhang   +2 more
doaj   +1 more source

Impact of increased aspartate aminotransferase to alanine aminotransferase (De Ritis) ratio in prognosis of testicular cancer [PDF]

Investigative and Clinical Urology, 2019
Purpose: Imaging studies can show metastasis in testicular cancer (TCa); however, a test for risk of metastasis in TCa has not been described. The ratio of aspartate aminotransferase to alanine aminotransferase, also called the De Ritis ratio (DRR), is ...
Sacit Nuri Gorgel, Yigit Akin, Esra Meltem Koc, Osman Kose, Serkan Ozcan, Yuksel Yilmaz   +5 more
doaj   +1 more source

Demographic and Clinical Characteristics of 907 Cases with Naltrexone Intoxication; a 14-Year Cross-Sectional Study

Archives of Academic Emergency Medicine, 2022
Introduction: Opioids have been the leading cause of death from poisoning in Iran for several years. This study aimed to evaluate the clinical and para-clinical presentations of naltrexone intoxication, its toxic dose, and its epidemiological properties.
Mitra Rahimi, Alireza Kargar, Delara Hazegh Fetratjoo, Sayed Masoud Hosseini, Arezou Mahdavinejad, Shahin Shadnia   +5 more
doaj   +1 more source

The Role of Connexin in Cutaneous Adverse Drug Reactions (CADRs) in Patients with Increasing Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT)

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2021
Background: The occurrence of Cutaneous Adverse Drug Reactions (CADRs) is relatively rare but can be fatal when causing organ failure, especially in the liver. The supporting examinations to determine liver injury are aspartate aminotransferase (AST) and
Dyah Ayu Mira Oktarina, Gilang Baswara, Hardyanto Soebono   +2 more
doaj   +1 more source

Protocol TOP-Study (tacrolimus organ perfusion): a prospective randomized multicenter trial to reduce ischemia reperfusion injury in transplantation of marginal liver grafts with an "ex vivo" tacrolimus perfusion [PDF]

, 2013
Background: Critical organ shortage results in the utilization of extended donor criteria (EDC) liver grafts. These marginal liver grafts are prone to increased ischemia reperfusion injury (IRI) which may contribute to deteriorated graft function and ...
Angele, Martin Kurt, Eder, Michael, Heise, Michael, Jauch, Karl-Walter, Nadalin, Silvio, Pascher, Andreas, Pratschke, Sebastian, Schemmer, Peter, Scherer, Marcus N., Ulrich, Frank, Wolters, Heiner, Wöhling, Dirk   +11 more
core   +1 more source

Immunoglobulin-Complexed Aspartate Aminotransferase.

Internal Medicine, 1993
We report a case of increased aspartate aminotransferase (AST, EC 2.6.1.1; GOT) in a 17-year-old girl which persisted for 3 years. The patient was healthy, but a high level of serum AST was detected during a school health check. Further examination revealed that AST was increased to as high as 259 IU/l while alanine aminotransferase (ALT) was normal ...
S, Matama, H, Ito, S, Tanabe, A, Shibuya, H, Shibata, K, Saigenji, K, Sakurai, M, Hasegawa   +7 more
openaire   +2 more sources

Crystal structure of L-aspartate aminotransferase from Schizosaccharomyces pombe.

PLoS ONE, 2019
L-aspartate aminotransferase is a pyridoxal 5'-phosphate-dependent transaminase that catalyzes reversible transfer of an α-amino group from aspartate to α-ketoglutarate or from glutamate to oxaloacetate.
Soo Yeon Jeong, Hyeonseok Jin, Jeong Ho Chang   +2 more
doaj   +1 more source

Serum Aminotransferase Level in Rhabdomyolysis according to Concurrent Liver Disease

The Korean Journal of Gastroenterology, 2019
Background/Aims: The serum aminotransferase level is usually elevated in rhabdomyolysis, and these enzymes originate from the skeletal muscle. On the other hand, there is limited data showing whether the degree of elevation of these enzymes differs ...
Kyeong Min Jo, Nae-Yun Heo, Seung Ha Park, Young Soo Moon, Tae Oh Kim, Jongha Park, Joon Hyuk Choi, Yong Eun Park, Jin Lee   +8 more
doaj   +1 more source