Results 11 to 20 of about 85,064 (291)
Improved l-Leucine Production in Corynebacterium glutamicum by Optimizing the Aminotransferases
Molecules, 2018 The production of branched-chain amino acids (BCAAs) is still challenging, therefore we rationally engineered Corynebacterium glutamicum FA-1 to increase the l-leucine production by optimizing the aminotransferases.
Li-Yan Feng +2 more
doaj +2 more sources
Crystal structure of L-aspartate aminotransferase from Schizosaccharomyces pombe.
PLoS ONE, 2019 L-aspartate aminotransferase is a pyridoxal 5'-phosphate-dependent transaminase that catalyzes reversible transfer of an α-amino group from aspartate to α-ketoglutarate or from glutamate to oxaloacetate.
Soo Yeon Jeong +2 more
doaj +2 more sources
Towards the directed evolution of an L-aspartate oxidase from Pseudomonas putida [PDF]
, 2012 Amino acid oxidases (AAOs) are enantioselective flavoenzymes that catalyse the oxidation of amino acids into imino acids, which spontaneously hydrolyse in water to form keto acids. AAOs have several potential applications, most notably as biocatalysts in
Leese, Charlotte
core +6 more sources
International Journal of Preventive Medicine, 2013 Background : Non-alcoholic steatohepatitis (NASH) is a clinicopathological entity that is being recognized more frequently in recent years. This study aimed to evaluate the effects of Metformin, with and without a probiotic supplement on liver ...
Ahmad Shavakhi +5 more
doaj +1 more source
Beyond Hy's Law: Importance of Markedly Elevated Aminotransferases without Hyperbilirubinemia. [PDF]
Clin Pharmacol TherElevated aminotransferases with concomitant jaundice in drug‐induced liver injury (DILI) are associated with adverse outcomes, but the prognostic significance of very high aminotransferases without jaundice is unclear.
Chalasani N +10 more
europepmc +2 more sources
MACRO-ASPARTATE AMINOTRANSFERASE
Hepatology and Gastroenterology, 2021 Measurement of serum enzyme activity is one of the most common laboratory tests. Increased activity may be caused by abnormal enzymes with a high molecular mass, the so-called macroenzymes. Macroenzymes may be seen in healthy subjects, but can also be related to disease. Macro-aspartate aminotransferase (macro-AST) is a macroenzyme that results from an
N. N. Silivontchik +3 more
openaire +2 more sources
The role of alanine and aspartate aminotransferases in C4 photosynthesis [PDF]
, 2019 Schlüter U, Bräutigam A, Droz J-M, Schwender J, Weber APM. The role of alanine and aspartate aminotransferases in C<sub>4</sub> photosynthesis. Plant Biology.
Droz, J.-M. +4 more
core +1 more source
Amifostine inhibits acrylamide-induced hepatotoxicity by inhibiting oxidative stress and apoptosis [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Acrylamide (ACR) is a toxic chemical agent that can induce hepatotoxicity through different mechanisms including oxidative stress and apoptosis. Amifostine is an important hepatoprotective and anti-oxidant compound.
Mostafa Karimi +3 more
doaj +1 more source
Lycopene and resveratrol pretreatment did not interfere with the liver of hepatectomized rats [PDF]
Acta Cirúrgica Brasileira, 2017 Purpose: To investigate the effects of lycopene and resveratrol pretreatment on hepatic hyperplasia in partially hepatectomized rats. Methods: The lycopene group and the resveratrol group received 40 mg/kg/day of lycopene or resveratrol, respectively ...
Pedro Paulo Barros +5 more
doaj +1 more source
Toxicology Reports, 2023 Over time, the use of plant-derived agents in the management of various human health conditions has gained a lot of attention. The study assessed the hepatoprotective potential of ethyl acetate fraction Tamarindus indica leaves (EFTI) during prenatal ...
Helen Ruth Yusuf +12 more
doaj +1 more source