Results 341 to 350 of about 464,951 (372)
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Alanine Aminotransferase and Aspartate Aminotransferase in Leishmania tarentolae1
The Journal of Protozoology, 1971SYNOPSIS. Culture stages (promastigotes) of Leishmania tarentolae were tested for alanine aminotransferase (E.C.2.6.1.2) and aspartate aminotransferase (E.C.2.6.1.1.). Neither enzyme was detected in crude cell extracts. After starch block electrophoresis, however, both transaminase activities were found in proteins migrating toward the anode. Only one
Stuart M. Krassner, Daryl S. Fair
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Development of an electrochemical immunosensor for alanine aminotransferase
Biosensors and Bioelectronics, 2003Alanine aminotransferase (ALT) has been regarded as one of the most sensitive indicators of hepatocellular damage. While ALT is widely used in the practice of medicine, few attempts have been made to develop biosensors applicable to the on-site diagnosis of liver diseases.
Eui Yul Choi +2 more
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Serum Alanine Aminotransferase and Seronegative Hepatitis
Annals of Internal Medicine, 1988Excerpt To the editor: Previous studies (1, 2) have established a direct relation between elevated alanine aminotransferase (ALT) levels in donor blood and the risk for post-transfusion hepatitis.
Peter J. Meier, Martin Schmid
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Stability of serum alanine aminotransferase activity
Transfusion, 1987In this study the authors examine the effects of common storage and handling procedures on serum alanine aminotransferase (ALT) levels. Clotted blood samples from 14 subjects were centrifuged at 280 × g for 10 minutes. Serum was tested immediately for baseline ALT levels and aliquots were stored at 22, 4, −20, and −80 ° C. Additional serums were stored
R Y Dodd +3 more
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Alanine Aminotransferase in Clinical Practice
Archives of Internal Medicine, 1991Alanine aminotransferase is an enzyme produced mainly in the liver. When serum activity is measured, it provides a marker of hepatic disease. This review explores the biochemistry and laboratory analysis of alanine aminotransferase in terms of its significance in human health and disease.
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Alanine Aminotransferase in Clinical Practice
Archives of Internal Medicine, 1992To the Editor. — The thoughtful review by Sherman 1 provides a useful approach to the practicing physician. He makes the recommendation that elevations of alanine aminotransferase levels less than twofold not be pursued even if they persist for 6 weeks or more. Although this appears a useful strategy in general, some forms of liver disease may benefit
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Radioisotopic assay of aspartate and alanine aminotransferase
Clinical Biochemistry, 1992The activities of aspartate and alanine aminotransferases in biological samples were assessed through a novel and sensitive procedure, based on the conversion of [U-14C]2-ketoglutarate to L-[U-14C]glutamate. In human plasma, the generation of L-[U-14C]glutamate was proportional to the volume of plasma (20-60 microL) and to the length of incubation (30 ...
Perales, Miguel Angel +2 more
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Inactivation of alanine aminotransferase by the neurotoxin β-cyano-L-alanine
Biochemical and Biophysical Research Communications, 1980Abstract β-Cyano-L-alanine inactivates pig heart alanine aminotransferase. The nitrile and enzyme form a freely dissociable Michaelis complex which rearranges to a form of inactive enzyme. The inactivated enzyme slowly recovers activity at 25° in 100 mM phosphate buffer, pH 7.4. The observations are consistent with a mechanism of inactivation similar
Leena Mela +3 more
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Screening of Donor Blood for Alanine Aminotransferase
JAMA: The Journal of the American Medical Association, 1985To the Editor.— Silverstein et al 1 advocate alanine aminotransferase (ALT) screening of donor blood because it will be cost-effective over a wide range of ALT levels. What the authors obviously did not take into consideration is that many chronic carriers of non-A, non-B hepatitis are asymptomatic with occasionally elevated ALT levels.
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Serum aspartate and alanine aminotransferase in filariasis
Clinica Chimica Acta, 1985Serum aspartate aminotransferase level in filarial patients was estimated. The level was compared against the level of the same enzyme in non-filarial patients. Similarly estimated and compared was the level of serum alanine aminotransferase in the same groups of subjects.
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