Results 121 to 130 of about 175,083 (295)

Enzymatic resolution for the preparation of enantiomerically enriched D-beta-heterocyclic alanine derivatives using Escherichia coli aromatic L-amino acid transaminase

open access: yes, 2004
An enzymatic resolution was carried out for the preparation of enriched beta-heterocyclic D-alanine derivatives using Escherichia coli aromatic L-amino acid transaminase.
Kinnera, Koteshwar   +5 more
core   +1 more source

Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang   +10 more
wiley   +1 more source

Metabolic Factors Associated with Alanine Transaminase Levels in Non-Alcoholic Fatty Liver Disease

open access: yesProceedings
Background: Non-Alcoholic Fatty Liver Disease is the most increasing chronic liver condition with a global prevalence of 30%. Metabolic factors like Obesity, Diabetes Mellitus are considered as major risk factors.
Safwa Mahmood   +5 more
doaj   +3 more sources

Multi‐Axis Stretchable Zippers for Personalized Wound Healing

open access: yesAdvanced Science, EarlyView.
Multi‐axis stretchable zippers can adapt to complex wound morphologies and enable personalized wound treatment through programmable contraction. This morphological matching strategy helps accelerate wound closure, improve blood perfusion, promote epithelial regeneration, and enhance collagen remodeling, pioneering new directions for personalized and ...
Siyuan Cai   +16 more
wiley   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

open access: yesAdvanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang   +10 more
wiley   +1 more source

Aspartate aminotransferase - risk marker for type-2 diabetes mellitus or red herring? [PDF]

open access: yes, 2014
Apekey, Tanefa A.   +12 more
core   +1 more source

Evidence of hemin as an end product inhibitor of L-alanine:4,5-dioxovalerate transaminase in rat liver mitochondria

open access: yes, 1985
This study describes the in vitro and in vivo effect of hemin on L-alanine:4,5-dioxovalerate transaminase activity. Hemin was shown to be an inhibitor of the purified enzyme and this inhibition was proportional to the concentration of hemin. The examined
Shanker, J.   +3 more
core   +1 more source

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