Results 141 to 150 of about 175,083 (295)

Phenotypical characterisation of a putative -amino acid transaminase in the yeast Scheffersomyces stipitis

open access: yes, 2019
Phylogenetic analysis of class III transaminases in the budding yeasts Lachancea kluyveri, Saccharomyces cerevisiae and Scheffersomyces stipitis identified a hitherto uncharacterised Sch.
Sveriges lantbruksuniversitet.   +1 more
core   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun   +10 more
wiley   +1 more source

Study Of Serum Alanine Transaminase: Serum Lactate Dehydrogenase Ratio for Typhoid Hepatitis

open access: yesNational Journal of Community Medicine, 2016
Introduction: Typhoid hepatitis clinically mimics acute viral hepatitis. Differentiation between these two illnesses is very important as typhoid hepatitis requires definitive treatment in form of antimicrobial drugs.
Panchsila B Damor   +5 more
doaj  

CLONING GENERAL TRANSAMINASE GENES IN ESCHERICHIA COLI K-12 AND MULTICOPY SUPPRESSION

open access: yes, 1987
Four general transaminase genes aspC, ilvE, avtA and tyrB, which encode transaminase A, transaminase B, transaminase C and transaminase D, respectively, were cloned in vivo using a miniMu plasmid element.
WANG, MING-DER
core  

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

open access: yesAdvanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu   +12 more
wiley   +1 more source

Liver Stiffness Measurement can Predict Liver Inflammation in Chronic Hepatitis B Patients with Normal Alanine Transaminase. [PDF]

open access: yesJ Clin Transl Hepatol, 2023
Huang LL   +12 more
europepmc   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng   +14 more
wiley   +1 more source

Efek Ekstrak Ciplukan (Physalis angulata L.) terhadap Kadar Alanine Transaminase (ALT) Tikus Model Diabetes Melitus [PDF]

open access: yes
Pendahuluan: Diabetes melitus merupakan penyakit kronis yang disebabkan ketidakmampuan tubuh untuk menghasilkan insulin yang cukup, menggunakan insulin secara efektif, atau keduanya.
IDZNI, Farisah
core  

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