Results 291 to 300 of about 321,126 (349)

High-normal and abnormal alanine transaminase levels linked to increased risk of hepatoma following treatment for chronic hepatitis C

Yen‐Chun Chen, Pei‐Chien Tsai, Chung-Feng Huang, Chi-Yi Chen, Chao‐Hung Hung, Chien‐Hung Chen, Chi‐Ming Tai, Pin‐Nan Cheng, Hsing‐Tao Kuo, Lein-Ray Mo, C. Lo, Yi‐Hsiang Huang, Han‐Chieh Lin, Pei‐Lun Lee, Ming‐Jong Bair, Te‐Sheng Chang, Chun‐Yen Lin, Szu‐Jen Wang, Tsai‐Yuan Hsieh, Tzeng-Hue Yang, Cheng‐Yuan Peng, Chi‐Chieh Yang, Lee‐Won Chong, Chien‐Wei Huang, Chih‐Wen Lin, Cheng‐Hsin Chu, Ming‐Chang Tsai, Jia‐Horng Kao, Chun‐Jen Liu, Wan‐Long Chuang, Kuo‐Chih Tseng, Ming‐Lung Yu   +31 more
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Targeting SPHK1 in macrophages remodels the tumor microenvironment and enhances anti‐PD‐1 immunotherapy efficacy in colorectal cancer liver metastasis

Cancer Communications, EarlyView.
Abstract Background Colorectal cancer liver metastasis (CRLM) is characterized by an immunosuppressive microenvironment and a blunted response to immunotherapy. Notably, tumor‐associated macrophages (TAMs) play a critical role in modulating immune responses and exhibit significant heterogeneity in CRLM.
Yizhi Zhan, Jinsong Xu, Zhanqiao Zhang, Yating Hu, Yongsheng Li, Junying Qian, Yunyan Ling, Dehua Wu, Haijun Deng, Guoxin Li, Zhiyong Shen, Yuan Fang   +11 more
wiley   +1 more source

Stereotactic body radiotherapy plus cadonilimab (PD‐1/CTLA‐4 bispecific antibody) as third‐line or beyond therapy for refractory solid tumors: A phase 1b study

Cancer Communications, EarlyView.
Abstract Background Cadonilimab is a humanized immunoglobulin G1 bispecific antibody targeting programmed cell death protein 1 (PD‐1) and cytotoxic T‐lymphocyte‐associated antigen 4 (CTLA‐4). This study aimed to evaluate the safety and efficacy of stereotactic body radiotherapy (SBRT) combined with cadonilimab in patients with advanced recurrent or ...
Yao Xiao, Yuxia Wang, Jun Li, Cheng Cheng, Chunyong Song, Xin Wang, Liyuan Tao, Hongqing Zhuang   +7 more
wiley   +1 more source

Reply to the comment on “High-normal and abnormal alanine transaminase levels linked to increased risk of hepatoma following treatment for chronic hepatitis C”

Yen‐Chun Chen, Ming‐Lung Yu
openalex   +1 more source

Applying Enzymatic Cascades for ISCPR in ω-transaminase Systems [PDF]

, 2014
Janes, Kresimir
core  

Lupeol‐Loaded Liposomes: Triple‐Negative Breast Cancer (TNBC) Cytotoxicity and In Vivo Toxicological Evaluation

Chemistry &Biodiversity, EarlyView.
ABSTRACT Lupeol is a natural product commonly found in many vegetables and fruits in significant quantities. Previous studies have demonstrated the relevant activity of lupeol against various tumor cell lines, suggesting that the natural product could be a promising agent for cancer treatment.
Daniel Crístian Ferreira Soares, Daniel Bragança Viana, André Luis Branco de Barros, Sued Eustáquio Mendes Miranda, Daniela Sachs, Eduardo Henrique Martins Nunes, Eryvaldo Sócrates Tabosa do Egito   +6 more
wiley   +1 more source

The physio-affective symptoms of Long COVID are strongly predicted by the severity of the acute infectious phase, and lowered antioxidants, nitric oxide, and alanine transaminase levels.

Michael Maes, Chavit Tunvirachaisakul, Laura de Oliveira Semeão, Ana Paula Michelin, Andressa Keiko Matsumoto, Francis F. Brinholi, Décio Sabbatini Barbosa, Yingqian Zhang, Pimpayao Sodsai, Nattiya Hirankarn, Abbas F. Almulla   +10 more
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Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

The Effect of Potentially Hepatotoxic Medicinal Products on Alanine Transaminase Levels in COVID-19 Patients: A Case–Control Study

В. И. Петров, A. Yu. Ryazanova, N. S. Tokareva   +2 more
openalex   +1 more source

Chemoenzymatic Route toward a De Novo Enantioselective Total Synthesis of (S)‐Baclofen Based on Metal‐Catalyzed Hydroformylation and Enzymatic Transamination

ChemBioChem, EarlyView.
A unique chemoenzymatic synthesis route toward (S)‐baclofen is presented, which highlights a hydroformylation and biocatalysis step toward the synthesis of such a challenging β‐chiral amino acid. The shown methodology exhibits high conversions and enantiomeric excess and is transferable to other β‐chiral amines and amino acids.
Feodor Belov, Hannah Bork, Luise Hänel, Manideep V. Kollipara, Matthias Höhne, Harald Gröger, Jan von Langermann   +6 more
wiley   +1 more source