Results 51 to 60 of about 129,755 (297)

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Effects of ochratoxin and T-2 toxin combination on performance, biochemical and immune status of commercial broilers

Veterinary World, 2013
Aim: To study the effects of Ochratoxin A(OA), T-2 toxin (T-2) and their combinations on the performance, biochemical andimmune status of broiler chickens.Materials and Methods: 168 day-old Cobb broiler chicks, obtained from a commercial hatchery were ...
H. C. Indresh, B. Umakantha
doaj   +1 more source

Biochemical screening of Hisex brown cross chickens after multiple vaccinations

Ukrainian Journal of Veterinary and Agricultural Sciences, 2023
It is impossible to imagine the epizootic well-being of poultry without immunoprophylaxis. Today, there are many vaccines to prevent infectious diseases in poultry.
T. S. Budnik, S. V. Guralska
doaj   +1 more source

Some Biochemical, Haematological and Histological Responses to a Long Term Consumption of Telfairia occidentalis-Supplemented Diet in Rats [PDF]

, 2009
Some biochemical, haematological and histological responses were studied in rats undergoing a long term feeding with a Telfairia occidentalis-supplemented diet.
Iweala, E. E. J., Obidoa, O.
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Investigation of the active site of an unclassified glutathione transferase in Bombyx mori by alanine scanning.

Journal of pesticide science, 2020
Glutathione transferase (GST) is an important class of detoxification enzymes that are vital for defense against various xenobiotics and cellular oxidative stress. Previously, we had reported an unclassified glutathione transferase 2 in Bombyx mori (bmGSTu2) to be responsible for detoxifying diazinon.
Yamamoto, Kohji, Yamaguchi, Misuzu, Yamada, Naotaka   +2 more
openaire   +2 more sources

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Acute hepatitis due to dengue virus in a chronic hepatitis patient

Brazilian Journal of Infectious Diseases
We present a case of acute hepatitis caused by dengue virus, with a significant increase in aspartate transferase and alanine transferase levels in a chronic hepatitis patient attended at the Cane Sugar Planters Hospital of Campos dos Goytacazes, RJ.
L.J Souza, J.M.C.O. Coelho, E.J. Silva, M. Abukater, F.C.R. Almeida, A. S. Fonte, L.A. Souza   +6 more
doaj   +1 more source

Associations between the K232A polymorphism in the diacylglycerol-O-transferase 1 (DGAT1) gene and performance in Irish Holstein-Friesian dairy cattle [PDF]

, 2010
peer-reviewedSelection based on genetic polymorphisms requires accurate quantification of the effect or association of the polymorphisms with all traits of economic importance. The objective of this study was to estimate, using progeny performance data
Berry, Donagh, Howard, Dawn J., Kearney, J.F., McCabe, Matthew, O'Boyle, Padraig, Waters, Sinead M.   +5 more
core  

A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria [PDF]

, 2005
Peer reviewedPublisher ...
Altschul, Asanuma, Ausubel, Barcenilla, Barker, Bennett, Blaut, Boynton, Buckel, Cleland, Cédric Charrier, Diez-Gonzalez, Donna Henderson, Duncan, Ewing, Ewing, Fischer, Garry J. Rucklidge, Gary J. Duncan, Gerhardt, Gordon, Harry J. Flint, Heider, Louis, Macfarlane, Mack, Martin D. Reid, Miller, Ochman, Pauline Young, Perkins, Petra Louis, Pryde, Rincon, Rustam I. Aminov, Scherf, Schweiger, Selmer, Skantar, Smith, Söhling, Sramek, Tung, Valentin, Valerie J. Russell, Walter, Wächtershäuser, Wiesenborn, Wilkins   +48 more
core   +1 more source