Results 91 to 100 of about 141,247 (306)

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh   +8 more
wiley   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

open access: yesAdvanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen   +11 more
wiley   +1 more source

利用导波震相分析阿拉斯加俯冲带东端Yakutat地体的洋壳结构特征

open access: yesDizhen xuebao
低速俯冲洋壳附近震源激发的部分地震波被困在低速层内以导波传播,弧前地震台站所记录的导波可用于洋壳结构成像。阿拉斯加俯冲带具有丰富的地震事件且布设了相对密集的永久性地震台站,为利用导波探测洋壳结构提供了天然试验场。本文对区域密集台站记录到的阿拉斯加俯冲带东端Yakutat地体两侧中源地震事件的导波震相传播特征进行了深入分析。结果显示:阿拉斯加俯冲带东端的Yakutat地体范围内,受低速俯冲洋壳影响的导波震相到时延迟随传播距离的增大而增加 ...
Xiaoyu Guan, Yuanze Zhou
doaj   +1 more source

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

open access: yesAdvanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira   +18 more
wiley   +1 more source

Unraveling Energy Flow Mechanisms in Semiconductors by Ultrafast Spectroscopy: Germanium as a Case Study

open access: yesAdvanced Science, EarlyView.
A multi‐technique pump‐probe setup capable of performing both transient reflectivity and time‐resolved Raman spectroscopy after ultrafast excitation, provides a comprehensive understanding of ultrafast electronic and phononic processes. Distinct decay rates for the temperature, frequency, and linewidth of the phonon mode in germanium are observed ...
Grazia Raciti   +10 more
wiley   +1 more source

Gravity‐Tolerant In‐Flight 3D Bioprinting Enabled by Stereolithography for Space Tissue Engineering

open access: yesAdvanced Science, EarlyView.
A flight‐compliant, closed stereolithographic 3D bioprinting system enables robust fabrication of acellular and cell‐laden hydrogel constructs under varying gravitational conditions, including microgravity and hypergravity phases. Printed structures retain dimensional fidelity and high‐resolution features, while cell viability remains high ...
Bianca Lemke   +8 more
wiley   +1 more source

In Situ Disentangling Local Thermal and Photoelectron Contribution in Photoelectrochemical Reactions Based on Optical Microfiber Sensors

open access: yesAdvanced Science, EarlyView.
An in situ optical microfiber sensor capable of real‐time decoupling of photothermal and photoelectronic effects in photoelectrochemical reactions is presented. The approach utilizes highly sensitive modal interference to dynamically capture localized thermo‐optic signals from photothermal materials, thereby enabling quantitative discrimination of ...
Guangzheng Luo   +4 more
wiley   +1 more source

Alaskapox amid New Orthopox Viral Infections Mikhail V. Supotnitskiy

open access: yesВестник войск РХБ защиты
A previously unknown virus from the orthopoxvirus family (OPXV) caused a series of smallpox-like diseases among the inhabitants of Alaska. A patient with immunodeficiency died from a generalized infection similar to smallpox.
M. V. Supotnitskiy
doaj   +1 more source

Neural Network‐Based Permittivity Engineering of Magnetic Absorbers for Customizable Microwave Absorption

open access: yesAdvanced Science, EarlyView.
A neural network‐enabled permittivity engineering paradigm is introduced, transcending traditional trial‐and‐error design. By decoupling electromagnetic parameters and screening a high‐throughput feature space, an ultrathin (1.0 mm) magnetic absorber is inversely designed, experimentally achieving a superior and customizable 5.1 GHz bandwidth and ...
Chenxi Liu   +9 more
wiley   +1 more source

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