Results 151 to 160 of about 216,635 (309)

Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium

Advanced Science, EarlyView.
Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed, Zicheng Deng, Arnab Misra, Marcus Orzabal, Ananya Kondapally, Enhong Li, Jonathan Do, Ying‐Wei Lan, Fatemeh Kohram, Hunter Blackburn, Andreas Damianos, Tanya V. Kalin, Vladimir V. Kalinichenko   +12 more
wiley   +1 more source

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

Advanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun, Rohan Narayan, Santhosh Kambaiah Nagaraj, Rishad Shiraz, Abinaya Kaliappan, Sumandeep Kaur, Ankur Singh, Siva Shanmugam Selvaraj, Gudepalya Renukaiah Rudramurthy, Chakenahalli Naveenkumar, Shridhar Narayanan, Radha Krishan Shandil, Shailly Tomar, Shashank Tripathi   +13 more
wiley   +1 more source

Alaska CVISN level one : top level design

Within the context of the National ITS Architecture, the Commercial Vehicle Information Systems Networks Program or CVISN is a dynamic program with flexible components and operating topologies, capable of adopting and implementing new and different ...
Alaska. Department of Transportation and Public Facilities
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A history of the United States Forest Service in Alaska /

, 2002
"R10-FR-5"--Cover.Includes index."2002 reprint by the USDA Forest Service.""June 2002"--Cover.Shipping list no.: 2002-0255-P.Originally published: Anchorage, Alaska : Alaska Historical Commission, Dept.
Rakestraw, Lawrence., United States. Forest Service. Alaska Region.   +1 more
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They say they have ears through the ground: animal essays from Southwest Alaska

, 2020
Includes bibliographical references and index.Translations by Alice Rearden, Marie Meade, David Chanar, Rebecca Nayamin, and Corey Joseph.Texts in English and Yupik.Lifeways in Southwest Alaska today remains inextricably bound to the seasonal cycles of ...
Meade, Marie, author, Fienup-Riordan, Ann, author, Rearden, Alice, author, Nayamin, Rebecca, author, Joseph, Corey, author, Chanar, David, author, University of Alaska Press, publisher   +6 more
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Multicomponent Molecular Editing of Polybutadiene: From Design Space to Battery Function

Advanced Science, EarlyView.
Multicomponent molecular editing transforms polybutadiene into an 18‐member polymer library with tunable thermal properties, nanoscale organization, and molecular dynamics. Mapping this multidimensional design space reveals distinct molecular input–property relationships and guides the selection of a candidate electrolyte additive for lithium–sulfur ...
Janna Jeschke, Oghenegare Emmanuel Eyankware, Ioannis Moutsios, Loïc Vidal, Cyril Vaulot, Azra Kocaarslan, Angelina Sarapulova, Sonia Dsoke, Hatice Mutlu   +8 more
wiley   +1 more source

Molecular MRI Reveals Macrophage‐Enriched Peritumoral Immune Remodeling After Incomplete Ablation in Liver Cancer

Advanced Science, EarlyView.
Incomplete microwave ablation (iMWA) induced a spatially organized, macrophage‐rich immunosuppressive tumor microenvironment (TME) in orthotopic VX2 liver tumors. Molecular MRI enhanced with europium‐doped very small superparamagnetic iron oxide nanoparticles (Eu‐VSOP) noninvasively visualized this remodeling, showing preferential nanoparticle ...
Yubei He, Han Xu, Julian M. M. Rogasch, Nikolaus Berndt, Jing Guo, Eyk Schellenberger, Akvile Häckel, Luisa Heidemann, Friederike Hesse, Yu Liu, Justus Ramtke, Nicola Beindorff, Frank Hofheinz, Avan Kader, Michael Mülleder, Kathrin Textoris‐Taube, Bernd Hamm, Dominik N. Müller, Robin Schmidt, Ralf Hauptmann, Heike Traub, Mathias Schannor, Lynn Jeanette Savic   +22 more
wiley   +1 more source

Metals and PFAS concentrations in aquatic environments and fish of the Brooks Range, Alaska. [PDF]

Environ Monit Assess
Fraley KM, Snodgrass W, Kelly BT, Robards MD.   +3 more
europepmc   +1 more source

Low Participation and Risk Reduction Potential of Supplemental Crop Insurance in the United States

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Federally subsidized crop insurance is a cornerstone of U.S. farm risk management, yet policies with the greatest share of participation only trigger indemnities after losses exceed 15%. Supplemental insurance was introduced to cover part of this deductible, but participation remains largely unchanged.
Francis Tsiboe, Hunter Biram, Amy Hagerman   +2 more
wiley   +1 more source

Stabilization of Horseshoe Lake Road using Geofibers and Soil-Sement\uae [PDF]

G00005806-334659-68102DTFH70-09-E-00020S12609One solution to reducing the cost of importing gravel in areas where available soils are predominately silts andsands is to stabilize the local soils with geofibers and synthetic fluids.
Alaska University Transportation Center, Connor, Billy, Collins, Rodney   +2 more
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