Results 141 to 150 of about 121,309 (370)

Elevated cystatin-C concentration is associated with progression to prediabetes: the Western New York Study [PDF]

, 2007
OBJECTIVE – We conducted a nested case-control investigation to examine if elevated baseline concentrations of cystatin-C predicted progression from normoglycaemia to prediabetes over 6 years of follow-up from the Western New York Health Study. RESEARCH
Dmochowski, Jacek, Donahue, Richard P., Rafalson, Lisa B., Rejman, Karol, Stranges, Saverio, Trevisan, Maurizio   +5 more
core   +1 more source

Effect of Long‐Term Voclosporin Treatment on Renal Histology in Patients With Active Lupus Nephritis With Repeat Renal Biopsies

Arthritis &Rheumatology, EarlyView.
Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Methods Patients were randomized to voclosporin or placebo treatment for up to 3 years; all patients received mycophenolate mofetil and low‐dose glucocorticoids.
Brad H. Rovin, Clarissa Cassol, Samir V. Parikh, Amit Saxena, Neil Solomons, Vanessa Birardi, Ernie Yap, Clint W. Abner, David R. W. Jayne, Robert B. Huizinga   +9 more
wiley   +1 more source

Effect of Albuminuria on the State of Plasma Hemostasis in Patients with Essential Hypertension

Počki, 2016
In recent decades, numerous scientific works are devoted to the study of the clinical and prognostic significance of albuminuria, methods of its detection, as well as treatment measures aimed at controlling this pathological condition.
A.I. Pastushyna, O.M. Plenova
doaj   +1 more source

Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on All-Cause Mortality and Renal Outcomes in Patients with Diabetes and Albuminuria: a Systematic Review and Meta-Analysis

Kidney & Blood Pressure Research, 2018
Background/Aims: Whether angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARB) could benefit patients with diabetes and albuminuria remains controversial.
Kanran Wang, Jinbo Hu, Ting Luo, Yue Wang, Shumin Yang, Hua Qing, Q. Cheng, Qifu Li   +7 more
semanticscholar   +1 more source

Differences in Dynamics of Specific Antinuclear Antibodies and Their Susceptibility to B Cell–Targeting Treatment in Patients With Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective The presence of antinuclear antibodies (ANAs) is characteristic for systemic lupus erythematosus (SLE). Antibody dynamics over time are thought to reflect the cellular source of ANAs and their therapeutic targetability. Anti–double‐stranded DNA (anti‐dsDNA) is the most prevalent and well‐studied of all ANAs, and fluctuations in anti‐dsDNA ...
Hugo J. van Dooren, Mieke van Schaik, Annemarie L. Dorjée, Eline J. Arends, Meggan Mackay, Laura Cooney, David A. Fox, David Wofsy, Dawn Smilek, Cynthia Aranow, Maria Dall'Era, Tom W. J. Huizinga, Cees van Kooten, René E. M. Toes, Betty Diamond, Y. K. Onno Teng, Jolien Suurmond   +16 more
wiley   +1 more source

Temporal prevalence and prognostic impact of diabetes mellitus and albuminuria in heart failure with preserved ejection fraction

Cardiovascular Diabetology
Background Most patients with heart failure with preserved ejection fraction (HFpEF) have a metabolic phenotype in which comorbidities including diabetes mellitus play an important role.
Nousjka P. A. Vranken, Xinyu Li, Heleen Bouman, Sanne G. J. Mourmans, Anouk Achten, Arantxa Barandiarán Aizpurua, Hans-Peter Brunner-La Rocca, Christian Knackstedt, Vanessa P. M. van Empel, Jerremy Weerts   +9 more
doaj   +1 more source

Association of smoking and cardiometabolic parameters with albuminuria in people with type 2 diabetes mellitus: a systematic review and meta-analysis

Acta Diabetologica, 2019
AimsSmoking is a strong risk factor for albuminuria in people with type 2 diabetes mellitus (T2DM). However, it is unclear whether this sequela of smoking is brought about by its action on cardiometabolic parameters or the relationship is independent ...
D. Kar, C. Gillies, M. Nath, K. Khunti, M. Davies, S. Seidu   +5 more
semanticscholar   +1 more source

Research-based versus clinical serum creatinine measurements and the association of acute kidney injury with subsequent kidney function: findings from the Chronic Renal Insufficiency Cohort study. [PDF]

, 2020
Background:Observational studies relying on clinically obtained data have shown that acute kidney injury (AKI) is linked to accelerated chronic kidney disease (CKD) progression.
Anderson, Amanda H, Appel, Lawrence J, Chen, Jing, Feldman, Harold I, Go, Alan S, He, Jiang, Hsu, Chi-yuan, Hsu, Raymond K, Kusek, John W, Lash, James P, Liu, Kathleen D, McCulloch, Charles E, Navaneethan, Sankar D, Porter, Anna C, Rahman, Mahboob, Rao, Panduranga S, Tan, Thida C, Townsend, Raymond R, Wilson, F Perry, Xie, Dawei, Yang, Jingrong, Zhang, Xiaoming   +21 more
core  

The correlates of urinary albumin to creatinine ratio (ACR) in a high risk Australian Aboriginal community [PDF]

, 2013
Background: Albuminuria marks renal disease and cardiovascular risk. It was estimated to contribute 75% of the risk of all-cause natural death in one Aboriginal group.
A Cass, A Festa, A Jager, A Koroshi, A Paolicchi, AM Hodge, C Meisinger, C Tsioufis, DH Lee, DH Lee, DH Lee, DH Lee, EM Stuveling, FC Goetz, GV Prasad, J Cunningham, J Spencer, JB Whitfield, JB Whitfield, JB Whitfield, JC Konen, JH Warram, JR Greenfield, KG Rowley, KL Chien, KM Conigrave, KM Conlgrave, L Bathum, L Huo, M Nakamura, M Veroni, MA Albert, MS Anvari, N Tangri, O Wirta, P Jousilahti, R Drozdz, RJ Glassock, SH Li, SP McDonald, V Agrawal, W Hoy, WE Hoy, WE Hoy, WE Hoy, WE Hoy, Wendy E Hoy, X Guo, YM Smulders, Z Wang, Z Wang, Z Wang, Zaimin Wang, Zhiqiang Wang   +53 more
core   +2 more sources

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source